Results 221 to 230 of about 68,358 (287)

Selective Lipoprotein Removal Enables High‐Purity EV Isolation from Plasma via Aptamer‐Based Mesh Filtration

open access: yesSmall, EarlyView.
A novel affinity‐based mesh filtration system, ApoFilter, enables selective removal of plasma lipoproteins via sequential aptamer‐functionalized layers targeting ApoA1 and ApoB100. While EVs pass through unimpeded, (V)LDL and HDL are rapidly depleted.
SoYoung Jeon, YongWoo Kim, Sehyun Shin
wiley   +1 more source

Discovery of the High-Affinity Aptamer for Candidalysin Using a Dual-Mode Colorimetric-SERS Platform. [PDF]

open access: yesBiosensors (Basel)
Sun Y   +8 more
europepmc   +1 more source

Motorized DNAzymes Drive Enhanced Electrochemical Biosensing for Rapid Bacterial Detection

open access: yesSmall Methods, EarlyView.
The micromotor DNAzyme analyzer (Motolyzer) enables sensitive electrochemical detection of Legionella pneumophila proteins in unprocessed samples with high specificity. Upon target recognition, DNAzymes actively release redox barcodes, which are detected on DNA‐functionalized electrodes.
Amir Ali Akhlaghi   +9 more
wiley   +1 more source

Targeting coronaviral inflammation: aptamer-based strategies for emerging threats. [PDF]

open access: yesSignal Transduct Target Ther
Zhao Y   +17 more
europepmc   +1 more source

Advances in cholesterol and lipoproteins detection for healthcare: A review

open access: yesVIEW, EarlyView.
Cholesterol is one of the main biomarkers related to the development of cardiovascular diseases. Its detection still relies on traditional methods of analysis, such as gas and liquid chromatographies. Detection of free cholesterol in saliva with redox or enzymatic sensors or detection of lipoproteins in blood with aptamer sensors are currently the most
Jacopo Giaretta   +7 more
wiley   +1 more source

Multiplex visual nucleic acid detection via isothermal cascaded transcription of fluorescent RNA aptamers

open access: yesVIEW, EarlyView.
(1) Existing multiplex nucleic acid detection struggles to combine high sensitivity, visual readout, and instrument‐free use, which is vital for rapid infection and antibiotic resistance diagnosis. (2) We developed MAGIC, integrating isothermal cascaded amplification and fluorescent RNA aptamer transcription, achieving 10 aM sensitivity, 100% accuracy ...
Yu Tang   +9 more
wiley   +1 more source

The potential for biased signalling in the P2Y receptor family of GPCRs

open access: yesBritish Journal of Pharmacology, EarlyView.
The purinergic receptor family is primarily activated by nucleotides, and contains members of both the G protein coupled‐receptor (GPCR) superfamily (P1 and P2Y) and ligand‐gated ion channels (P2X). The P2Y receptors are widely expressed in the human body, and given the ubiquitous nature of nucleotides, purinergic signalling is involved with a plethora
Claudia M. Sisk   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy