Chemically modified DNA aptamers and DNAzymes for expanded functional capabilities. [PDF]
Zhang C +5 more
europepmc +1 more source
The Graphene Oxide Memristive DNA Sensor for Taxonomic Fingerprint
A graphene oxide–based memristive DNA sensor enables rapid, label‐free quantification of nucleotide base composition across 37%–55% GC with strong linear calibration. Delivering results within 2–5 min, the platform combines high sensitivity with minimal sample preparation, offering a practical tool for point‐of‐care diagnostics, genetic fingerprinting,
Konstantin G. Nikolaev +4 more
wiley +1 more source
Targeted biologics for TNBC: Advances in nanobodies, antibodies, peptides, and aptamers. [PDF]
Mashayekhi K +4 more
europepmc +1 more source
Nano Delivery Strategy Opens Effective Avenues for the Treatment of Colorectal Cancer
ABSTRACT Colorectal cancer (CRC) presents significant therapeutic challenges because of chemoresistance, systemic toxicity, and the complexity of the tumor microenvironment (TME). Nanodrug delivery systems (NDDS) have emerged as versatile platforms capable of overcoming these limitations by enhancing tumor accumulation, improving pharmacokinetics, and ...
Qiurong Wei +7 more
wiley +1 more source
Selection and characterization of a DNA aptamer for Patulin and its application in a label-free fluorescence assay for fruit juices. [PDF]
Wang S +5 more
europepmc +1 more source
Abstract Background Recent advances in proteomic profiling have enabled its use as a powerful approach in elucidating molecular mechanisms underlying Parkinson's disease, enabling the identification of disease‐associated protein alterations and candidate biomarkers for diagnosis, progression, and therapeutic response.
Victoria J. Dardov +21 more
wiley +1 more source
Designing molecular RNA switches with Restricted Boltzmann machines. [PDF]
Fernandez-de-Cossio-Diaz J +8 more
europepmc +1 more source
Intelligent nano‐platforms in breast cancer therapy: Current advances and future perspectives
The smart nano platform in breast cancer treatment is designed with advanced nanocarriers, including liposomes, hydrogels, porous nanoparticles, and aptamer‐based systems. These systems are capable of targeted drug release and response to environmental stimuli.
Tina Rahimi, Moluk Aivazi
wiley +1 more source
Evolution of Multivalent Aptamer Corona for High-Throughput Multiplexed Detection of Multiple Cancers. [PDF]
Wang M +10 more
europepmc +1 more source
DNA machinery represents a burgeoning frontier at the intersection of robotics and nanotechnology, evolving from static nanostructure toward dynamic nanorobots. Here, the authors review the comprehensive research pipeline of designer DNA‐based nanomachines, covering the design, analysis, and fabrication. These programmable systems enable transformative
Yiquan An +5 more
wiley +1 more source

