Results 181 to 190 of about 76,545 (327)

Aptamer-Based Delivery of Genes and Drugs Across the Blood-Brain Barrier. [PDF]

Pharmaceuticals (Basel)
Yang L, Yin Y, Liu X, Guo B.
europepmc   +1 more source

Micro/Nanorobot for Drug Delivery—A Review of Material Selections

Advanced NanoBiomed Research, EarlyView.
This review explores material strategies for biomedical micro/nanorobots, emphasizing their roles in propulsion, navigation, drug delivery, and biodegradability. It highlights advancements in metallic, polymeric, and hybrid materials, while addressing clinical translation challenges such as toxicity, immune response, and manufacturability.
Xiaozhuo Wu, Bingyun Li, Malcolm Xing
wiley   +1 more source

A Nonviral Neo‐Nucleocapsid for Cell‐Specific RNA Delivery Developed by Pseudo‐Cyclic Peptide Grafting and Directed Evolution

Angewandte Chemie, EarlyView.
Nonviral neo‐nucleocapsids developed from a repurposed bacterial protein cage, and macrocyclic peptide pharmacophores via protein‐protein ligation, bacteria‐based directed evolution, lasso‐grafting, and mammalian cell‐based directed evolution enabled cell specific RNA delivery.
Daiki Kanayama, Naohiro Terasaka, Kazuki Kato, Sae Okazaki, Hiroaki Suga   +4 more
wiley   +2 more sources

Characterisation of aptamer–target interactions by branched selection and high-throughput sequencing of SELEX pools [PDF]

, 2015
Daniel M. Dupont, Niels Larsen, Jan K. Jensen, Peter A. Andreasen, Jørgen Kjems   +4 more
openalex   +1 more source

Surface‐Coated Inorganic Nanomaterials for Drug Delivery: Chemical Design, Biomedical Applications, and Mechanistic Insights

Advanced NanoBiomed Research, EarlyView.
This review explores how surface‐coated inorganic nanomaterials are chemically engineered for advanced drug delivery. It highlights design principles, coating strategies, and biomedical applications, emphasizing how surface chemistry governs biocompatibility, targeting, and controlled release.
Hossein Daneshgar, Sepideh Ahmadi, Nikzad Abbariki, Navid Rabiee, Sidi A. Bencherif   +4 more
wiley   +1 more source

Ribocentre-aptamer: an integrative, structure-focused database for RNA aptamers. [PDF]

Nucleic Acids Res
Lu Z, Sun H, Fu B, Ao Y, Wang J, Chen K, Luo Y, Li L, Qiu Z, Zhao J, Sun Y, Tan Z, Liu Q, Ren Y, Guo Z, Chen X, He Y, Zhao Y, Chen Y, Li M, Peng X, Huang B, Zhu S, Huang L, Miao Z.   +24 more
europepmc   +1 more source

Complex formation with nucleic acids and aptamers alters the antigenic properties of platelet factor 4

, 2013
Miriam E. Jaax, Krystin Krauel, Thomas Marschall, Sven Van Brandt, Julia Gansler, Birgitt Fürll, Bettina Appel, Silvia Fischer, Stephan Block, Christiane A. Helm, Sabine Müller, Klaus T. Preissner, Andreas Greinacher   +12 more
openalex   +1 more source

Characterization of the specific interaction between the DNA aptamer sgc8c and protein tyrosine kinase-7 receptors at the surface of T-cells by biosensing AFM [PDF]

, 2017
Michael Leitner, Alexandra Poturnayová, Constanze Lamprecht, Sabine Weich, Maja Šnejdárková, Ivana Karpisova, Tibor Hianik, Andreas Ebner   +7 more
openalex   +1 more source

Mucin Glycoprotein Nanoparticles Enable a Selective Antisense Therapy for Oncogenic MicroRNAs

Advanced NanoBiomed Research, EarlyView.
Mucin glycoproteins are turned into nanoparticles by employing synthetic DNA strands, which have a dual function: they stabilize the nanoparticles and act as binding sites for intracellular miRNA‐21. Thus, upon internalization into tumor cells, these mucin nanoparticles can deplete miRNA‐21 from the cytosol, which induces apoptosis in vitro and in vivo.
Ceren Kimna, Thomas Mayer, Di Zhang, Matthias Marczynski, Carolin A. Rickert, Fabio Henkel, Lennart J. K. Weiss, Friedrich C. Simmel, Yuxia Luan, Oliver Lieleg   +9 more
wiley   +1 more source

Scalable Multiparametric Characterization of Aptamer-Target Interactions. [PDF]

ACS Nano
Sulliger M, Peters M, Sottini A, Stuber A, Yang K, Nakatsuka N, Ortega Arroyo J, Quidant R.   +7 more
europepmc   +1 more source