Results 161 to 170 of about 15,648 (185)

Reverse‐Engineered Lipid Nanoparticles Harness Protein Corona Formation for Cytokine Sequestration and Combination Immunomodulatory Therapy

Small, EarlyView.
Bioinspired triglyceride‐ceramide lipid nanoparticles were reverse‐engineered from cytokine‐sequestering plant‐derived nanoparticles to capture pathological inflammatory mediators through protein corona formation. Dexamethasone‐loaded TCNPs combine extracellular cytokine sequestration with intracellular immunomodulation, reducing IL‐6, TNF‐α, and NF‐κΒ
Junsik J. Sung, Gargi Yogesh Digholkar, Ryan M. Pearson   +2 more
wiley   +1 more source

Identification and Discrimination of Sulfated and Unsulfated Gut‐Hormone Biomarkers in Human Serum by Nanopore

Small, EarlyView.
This study discriminates between sulfated and unsulfated cholecystokinin‐8 gut‐hormone forms at single‐molecule‐level resolution. Using an aerolysin nanopore embedded in a hybrid lipid‐polymer membrane, the system produces distinct electrical signatures enabling highly sensitive detection, even in 20% human serum.
Luca Iesu, Laurent Bacri, Juan Pelta, Benjamin Cressiot   +3 more
wiley   +1 more source

Hoberman‐Inspired Reconfigurable DNA Origami Ring for Nanoscale Capture

Small, EarlyView.
A Hoberman‐inspired DNA origami ring with coupled scissor‐like motion is designed and assembled. Reversible reconfiguration produces different conformations for organization of gold nanoparticles and capture of DNA nanostructures with varied sizes and geometries. ABSTRACT Dynamic DNA origami systems have enabled programmable nanoscale motion and target‐
Henry Wisniewski, Minu Saji, Moisés Reyes, Qi Yang, Fei Zhang   +4 more
wiley   +1 more source

Mechanism‐Guided Engineering of Upconversion Nanoparticles for Antibacterial Phototherapy: From Photonic Principles to Translational Nanosystems

Small, EarlyView.
This review provides a systematic overview of the field of antibacterial PhotoDynamic Therapy (aPDT) triggered by upconversion nanoparticles (UCNPs), focusing on the mechanisms and the key factors that define their efficacy for generating bactericidal species upon NIR‐light activation.
Zhe Li, Calum Johnston, Barbara Lonetti, Clément Roux   +3 more
wiley   +1 more source

Aptamers for malaria diagnosis

, 2017
Tanner, JA
core  

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Aptamers from random sequence space: Accomplishments, gaps and future considerations

Analytica Chimica Acta, 2022
Sisi He, Dingran Chang, Yingfu Li
exaly  

Cell-specific aptamers as potential drugs in therapeutic applications: A review of current progress

Journal of Controlled Release, 2022
Wentao Xu, Xiaoyun He, Kunlun Huang
exaly  

Nucleic Acid Aptamers for Molecular Diagnostics and Therapeutics: Advances and Perspectives

Angewandte Chemie - International Edition, 2021
Cheng Cui, Long Li
exaly  

Current Perspectives on Aptamers as Diagnostic Tools and Therapeutic Agents

Pharmaceutics, 2020
Prabir Kumar Kulabhusan, Meral Yüce, Babar Hussain   +2 more
exaly  

High affinity truncated aptamers for ultra-sensitive colorimetric detection of bisphenol A with label-free aptasensor

Food Chemistry, 2020
Hongyan Zhang, Zhihua Li, Min Jia
exaly