Results 141 to 150 of about 41,171 (288)
Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles
Advanced NanoBiomed Research, EarlyView.This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley +1 more source
Miniaturized Conductometric Biosensor for Rapid Detection of TNF‐α in Saliva
Advanced NanoBiomed Research, EarlyView.A miniaturized conductometric sensor detects TNF‐α at femtomolar levels with high selectivity. The device enables noninvasive testing using pooled human saliva and supports smartphone‐based, real‐time resistance readings. This portable biosensor offers a practical alternative for monitoring TNF‐α, providing new opportunities for diabetes and related ...
Mingjie Yang +8 more
wiley +1 more source
Advances in BODIPY Derivatives for Antibacterial Phototherapy
Angewandte Chemie, EarlyView.This review systematically summarizes the design strategies and structure‐activity relationships of BODIPY‐based antibacterial phototherapy, covering molecular engineering of small‐molecule photosensitizers and nanoplatforms, bacterial targeting and carrier design, and discussing the challenges and future perspectives associated with clinical ...
Li Lv +9 more
wiley +2 more sources
Branched oligonucleotides as CathepsinG inhibitors
, 2013 New aptamers, based on branched oligonucleotides, are presented as CathepsinG ...
MUSUMECI, DOMENICA +5 more
core
Angewandte Chemie, EarlyView.Rationally designed DNA multivalent aptamers direct specific protein binding to drive self‐assembly into protein‐DNA frameworks (PDFs). Structurally defined protein‐aptamer interfaces organize proteins into triangles, linear and ladderlike chains, and periodic two‐dimensional arrays, enabling precise control over orientation, connectivity, and overall ...
Zhe Zhang +11 more
wiley +2 more sources
ChemistryOpenTetracyclines are a class of commonly used four‐ringed antibiotics. A series of DNA aptamers were recently obtained using the capture‐SELEX (systematic evolution of ligands by exponential enrichment) method to bind to oxytetracycline, and one of the ...
Yichen Zhao, Biwen Gao, Juewen Liu
doaj +1 more source
, 2017 When selecting for aptamers the probability of selecting the fittest aptamer is extremely low due to the stochastic nature of the selection and insufficient sequence space coverage of the initial library.
Fraser, LA +5 more
core
Angewandte Chemie, EarlyView.Ein elektrochemischer Aptamer‐Sensorchip nutzt Interdigitalelektroden mit selektiver Monoschicht‐Funktionalisierung, um Dopamin und Cortisol mittels robuster komplementärer „Signal‐Off/On“‐Antworten zu detektieren. Diese Dual‐Channel‐Signalumwandlung ermöglicht eine schnelle Detektion innerhalb von 5–30 min bei geringen Probenvolumina in künstlicher ...
Senyao Wang +12 more
wiley +1 more source
New findings on the anti-HIV activity of d(TGGGAG) aptamers
, 2016 Introduction: Recently, we reported the synthesis and characterization of a new mini-library of tetramolecular G quadruplexes based on the d(TGGGAG) sequence, which was previously shown to target the HIV-1 glycoprotein gp120. Oligodeoxynucleotides (ODNs)
Valeria, Romanucci +6 more
core
Pseudo aptamer expands aptamer’s applications [PDF]
MOJ Bioorganic & Organic Chemistry, 2018 Hengguang Li, Grace M Chavis
openaire +1 more source