Results 151 to 160 of about 78,567 (340)
Lipids in Health and DiseaseThe degradation of low-density lipoprotein receptor (LDLR) is induced by proprotein convertase subtilisin/kexin type 9 (PCSK9), resulting in elevated plasma concentrations of LDL cholesterol.
Maryam Mahjoubin-Tehran +5 more
doaj +1 more source
Structure-Guided Engineering of the Homodimeric Mango-IV Fluorescence Turn-on Aptamer Yields an RNA FRET Pair [PDF]
, 2020 Robert J. Trachman +6 more
openalex +1 more source
Advanced Science, EarlyView.A catalytic allosteric DNAzyme assay (SMART) is developed by engineering DNAzyme into a unimolecular biosensor, enabling highly sensitive and multiplex detection of small molecules and nucleic acids. SMART enables extraction‐free, one‐pot, one‐step, isothermal, and cost‐effective detection of biological markers, achieving >95% accuracy for rapid ...
Yanzhe Shen +12 more
wiley +1 more source
Advanced Science, EarlyView.This study presents an injectable DNA‐based porous hydrogel integrating catechol motifs and targeting aptamers for pulpitis management. Upon in situ crosslinking, the scaffold actively recruits endogenous dental pulp stem cells, restores redox homeostasis, and modulates immune responses.
Luhui Cai +9 more
wiley +1 more source
Inside Cover: Artificial Ribozyme Switches Containing Natural Riboswitch Aptamer Domains (Angew. Chem. Int. Ed. 15/2009) [PDF]
, 2009 Markus Wieland +3 more
openalex +1 more source
Metabolism‐Based Biomarkers for Rapid Phenotypic Antibiotic Susceptibility Testing
Advanced Science, EarlyView.Metabolic differences emerging after antibiotic exposure provide rapid phenotypic signals of susceptibility and resistance. This review summarizes metabolic biomarkers for rapid phenotypic AST, associated with nutrient uptake, respiratory activity, metabolic reprogramming, and enzymatic function. ABSTRACT The accelerating global crisis of antimicrobial
Sha Yu +7 more
wiley +1 more source
Advanced Science, EarlyView.A DNA‐functionalized biohybrid hydrogel is developed by integrating Cu‐mediated nucleic acid microflowers into a thermoresponsive matrix, enabling electrothermally triggered, on‐demand payload release. The platform offers spatiotemporally controllable therapeutic delivery with promising applications in precision oncology, neural regulation, and chronic
Mengqiu Sun +8 more
wiley +1 more source
Fundamentals of Aptamers and Aptamers-Based Biosensors
Antibodies or enzymes have long dominated the field of sensors and analysis, based on their most effective capture capacity for many target molecules as biorecognition. Because of this, immunoassay has developed into one of the best platforms for biosensors, including clinical diagnostics.
Cem Erkmen +3 more
openaire +3 more sources