(1) Existing multiplex nucleic acid detection struggles to combine high sensitivity, visual readout, and instrument‐free use, which is vital for rapid infection and antibiotic resistance diagnosis. (2) We developed MAGIC, integrating isothermal cascaded amplification and fluorescent RNA aptamer transcription, achieving 10 aM sensitivity, 100% accuracy ...
Yu Tang +9 more
wiley +1 more source
Design and Characterization of Aptamers to Antibiotic Kanamycin with Improved Affinity. [PDF]
Samokhvalov AV +3 more
europepmc +1 more source
The potential for biased signalling in the P2Y receptor family of GPCRs
The purinergic receptor family is primarily activated by nucleotides, and contains members of both the G protein coupled‐receptor (GPCR) superfamily (P1 and P2Y) and ligand‐gated ion channels (P2X). The P2Y receptors are widely expressed in the human body, and given the ubiquitous nature of nucleotides, purinergic signalling is involved with a plethora
Claudia M. Sisk +2 more
wiley +1 more source
Development of RNA Aptamers That Inhibit the RNA-Dependent RNA Polymerase Activity of SARS-CoV-2 Strains In Vitro. [PDF]
Song C, Lee SW.
europepmc +1 more source
Computational Analysis Uncovering Contrasts in G-Quadruplex Propensity and Aptamer Enrichment in SELEX-Derived Libraries. [PDF]
Liu G, Wu TY, Kwok CK, Liu J.
europepmc +1 more source
Aptamer-based approaches for sensitive detection and epitope mapping of SARS-CoV-2 spike protein. [PDF]
Poolsup S +20 more
europepmc +1 more source
Immobilization-free SELEX for aptamer discovery targeting colorectal cancer-derived small extracellular vesicles. [PDF]
Lee ES +5 more
europepmc +1 more source
Development of an impedimetric aptasensor for Shiga-like toxin 1 using a DNA aptamer and an interdigitated microelectrode. [PDF]
Mili M +3 more
europepmc +1 more source
Nanoparticle-based approaches for bacterial detection and therapy. [PDF]
Rajana VK +6 more
europepmc +1 more source

