Results 231 to 240 of about 41,171 (288)

Discovery and Cryo-EM-Guided Development of a Neuropilin-2-Binding Aptamer for Receptor Antagonism. [PDF]

J Am Chem Soc
Jiang K, Kacherovsky N, Wang T, Wu AY, Liu GW, Cardle II, Ureel J, Pippin JW, Salipante SJ, Shankland SJ, Pun SH.   +10 more
europepmc   +1 more source

DNA‐Enzyme Hybrid Nanostructures: Functional Materials to Modulate Enzymatic Activity

Small, EarlyView.
DNA–enzyme hybrid nanostructures enable precise spatial and stoichiometric control over enzyme organization, offering a powerful platform to modulate catalytic activity. This review critically evaluates key mechanistic hypotheses, including proximity effects, microenvironment changes, confinement, and stabilization, as well as highlighting ...
Manar Elnaggar, Amelie Heuer‐Jungemann
wiley   +1 more source

Nanoelectronic Detection of Opioids: Machine Learning‐Powered Screening With Carbon Nanotube Field‐Effect Transistor Sensor Array

Small, EarlyView.
A carbon nanotube field‐effect transistor (NTFET) sensor array is constructed to screen different opioids with machine learning models. Codeine, fentanyl, hydrocodone, and morphine are tested using the NTFET sensor array and classified with both conventional supervised learning models and deep learning models.
Zhengru Liu, Mehdy Dousty, Wenting Shao, Jieyu Wang, Samia Afrin, Wuqi Li, Ervin Sejdić, Alexander Star   +7 more
wiley   +1 more source

Development of DNA Aptamers Against <i>Leishmania infantum</i> GP63 Protein for Therapeutic and Diagnostic Applications. [PDF]

Pharmaceutics
Román-Álamo L, Currea-Ayala D, Oliveira GS, Fallica AN, Mooren T, Avalos-Padilla Y, Fernàndez-Busquets X.   +6 more
europepmc   +1 more source

Engineering Nanoscale Frontiers: Valve Metal Oxide Nanostructures From Fundamentals to Multifunctional Biomedical Applications

The Chemical Record, EarlyView.
Valve metal oxide nanostructures such as TiO2, Ta2O5, Nb2O5, ZrO2, and HfO2 are emerging as versatile biomedical platforms due to their tunable surface properties, exceptional stability, and inherent biocompatibility. This review highlights their synthesis, physicochemical properties, and biological interactions, addressing their roles in advanced ...
Nina Kummer, Désirée Gül, İdris Sargin, Mustafa Dolaz, Dzmitry Shcharbin, Shirley K. Knauer, Burcu Önal Acet, Emrah Dikici, Mingyuan Gao, Mehmet Odabaşı, Ömür Acet, Roland H. Stauber   +11 more
wiley   +1 more source

Quantum dot-DNA microsphere aptamer biosensor with AI-assisted structural modeling for rapid detection of the lung cancer biomarker USE1. [PDF]

J Nanobiotechnology
Kim MJ, Yum K, Kim D, Jang I, Park A, Jung M, Lee GD, Jin JO, Im W, Lee JB, Lee PC.   +10 more
europepmc   +1 more source

Two‐Dimensional Materials For Lateral Flow Assays: A Critical Review of Functional Roles and Translational Challenges

VIEW, EarlyView.
2D nanosheets, with large surface area, excellent optical/electrical properties, and high specificity, combine with lateral flow assay strips to enable rapid, readable detection, boosting the strips’ development and applications. Abstract Lateral flow assays (LFAs) are widely used for point‐of‐care diagnostics, but their detection capability remains ...
Weimin Xu, Ruping Liu, Na Gao, Jianxiao Zhu, Haowen Jiang, Shouzheng Jiao, Zhicheng Sun, Kai Shen, Gaolian Xu, Minghua Du, Ziyan Li, Yang Wang   +11 more
wiley   +1 more source

In silico conversion of ssRNA aptamers to ssDNA: molecular dynamics assessment of structural stability and conformational preservation. [PDF]

J Comput Aided Mol Des
Lorenti S, Alqualo NO, Moreira DC, Junior NN, Goulart VA.   +4 more
europepmc   +1 more source

Aptamers with magnetically tunable affinity for divalent cobalt ions. [PDF]

Nat Commun
Gao S, Wang L, Yao L, Mao Y, Eisenstein M, Soh HT, Zheng L.   +6 more
europepmc   +1 more source

A general strategy to enhance aptamer affinity by suppressing dissociation through symmetric assembly. [PDF]

Nucleic Acids Res
Zhang Z, Tian W, Gu J, Li J, Liu M, Soleymani L, Li Y.   +6 more
europepmc   +1 more source