Results 241 to 250 of about 41,171 (288)

A Real-Time Antifouling Multivalent Aptamer Platform for Wash-Free Electrochemical Detection of Low-Abundance Biomarkers in Human Plasma. [PDF]

Angew Chem Int Ed Engl
Sen P, Saxena S, Zhang Z, Sandhu N, Das P, Gu J, Hoare T, Li Y, Soleymani L.   +8 more
europepmc   +1 more source

Aptamer-Functionalized SWCNT Optical Sensors for Selective and Robust Dopamine Detection in Physiological Media. [PDF]

ACS Appl Nano Mater
Stefoni MC, Yafai H, Ryan AK, Israel A, Williams RM.   +4 more
europepmc   +1 more source

High-Affinity Six-Letter DNA XenoAptamer Generation by Genetic Alphabet Expansion. [PDF]

J Am Chem Soc
Matsunaga KI, Tan HP, Low JL, Kimoto M, Hirao I.   +4 more
europepmc   +1 more source

Translational opportunities in aptamer and nanobody lateral flow assays within the WHO REASSURED framework.

Sens Diagn
Monk ET, McConnell EM, McMullin DR, DeRosa MC.   +3 more
europepmc   +1 more source

Are aptamers better? Learning from malaria diagnosis

, 2018
Tanner, JA
core  

The Chemical Biology of Aptamers

Angewandte Chemie - International Edition, 2009
Aptamers are small single-stranded oligonucleotides that fold into a well-defined 3D structure and interact with high affinity and specificity with their target molecules, thereby inhibiting their biological functions.
Gunter Mayer
exaly   +6 more sources

Aptamers as therapeutics [PDF]

Nature Reviews Drug Discovery, 2010
Nucleic acid aptamers can be selected from pools of random-sequence oligonucleotides to bind a wide range of biomedically relevant proteins with affinities and specificities that are comparable to antibodies. Aptamers exhibit significant advantages relative to protein therapeutics in terms of size, synthetic accessibility and modification by medicinal ...
Anthony D Keefe, Andrew D Ellington
exaly   +3 more sources

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Aptamer chemistry

Advanced Drug Delivery Reviews, 2018
Aptamers are single-stranded DNA or RNA molecules capable of tightly binding to specific targets. These functional nucleic acids are obtained by an in vitro Darwinian evolution method coined SELEX (Systematic Evolution of Ligands by EXponential enrichment).
Röthlisberger, Pascal, Hollenstein, Marcel   +1 more
openaire   +3 more sources