Results 211 to 220 of about 88,342 (327)
Chemically modified DNA aptamers and DNAzymes for expanded functional capabilities. [PDF]
Zhang C +5 more
europepmc +1 more source
Marine silicon for biomedical sustainability
Schematic illustrating marine silicon for biomedical engineering. Abstract Despite momentous divergence from oceanic origin, human beings and marine organisms exhibit elemental homology through silicon utilization. Notably, silicon serves as a critical constituent in multiple biomedical processes.
Yahui Han +3 more
wiley +1 more source
Selection and characterization of a DNA aptamer for Patulin and its application in a label-free fluorescence assay for fruit juices. [PDF]
Wang S +5 more
europepmc +1 more source
Covalent Attachment of a Platinum(II) Complex inside DNA Duplexes
Oxidative addition is used for the site‐specific incorporation of an organometallic PtII complex as an artificial nucleobase into a DNA duplex. The platination stabilizes the duplex and confers it with phosphorescence. An organometallic phosphorescent PtII complex is introduced into DNA duplexes via oxidative addition to a tailor‐made artificial ...
Tim Schäfer +6 more
wiley +1 more source
Designing molecular RNA switches with Restricted Boltzmann machines. [PDF]
Fernandez-de-Cossio-Diaz J +8 more
europepmc +1 more source
Self‐Calibrating Ratiometric DNA Aptamer Probe for Quantitative ATP Imaging in Living Cells
We developed the RFA–ECHO probe, an internally calibrated ATP sensor that remains responsive across millimolar ATP levels. Its self‐correcting Cy5/ECHO ratio ensures accurate quantification independent of probe uptake. Compared with FRET‐based sensors, it yields a robust ratiometric shift, distinguishing high‐ATP cancer cells from normal ones, enabling
Yunsong Xu +5 more
wiley +1 more source
Integrating Magnetic Bead-Based SELEX with <i>In Silico</i> Binding Analyses for the Identification of High-Affinity DNA Aptamers Targeting TAGLN2. [PDF]
Martin DR +6 more
europepmc +1 more source
Mini‐Hairpin DNA: Extraordinarily Stable Structure and Its Applications
Mini‐hairpin DNA fragments containing GCGAAGC and GCGAAAGC form exceptionally stable hairpin‐like structures, with only two G−C pairs and one sheared G−A pair, remaining undenatured in 7 M urea and resisting nuclease digestion. These mini‐hairpin sequences frequently appear in replication and transcription origins, influence DNA sequencing fidelity ...
Michiko Kimoto, Ichiro Hirao
wiley +1 more source

