Results 81 to 90 of about 41,171 (288)

Aptamers in Therapeutics

open access: yesJOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2016
Aptamers are single strand DNA or RNA molecules, selected by an iterative process known as Systematic Evolution of Ligands by Exponential Enrichment (SELEX). Due to various advantages of aptamers such as high temperature stability, animal free, cost effective production and its high affinity and selectivity for its target make them attractive ...
openaire   +3 more sources

Development of an aptamer based lateral flow test strip for a diabetes biomarker [PDF]

open access: yes, 2019
>Magister Scientiae - MScDiabetes mellitus is one of the major chronic diseases that poses a significant risk to human health globally. Current diagnostics for diabetes are based on blood glucose measurements, which can go unnoticed for years. As such,
Moabelo, Koena Leah
core   +1 more source

Use of Magnetic Beads in Selection and Detection of Biotoxin Aptamers by Electrochemiluminescence and Enzymatic Methods

open access: yesBioTechniques, 2002
Systematic evolution of ligands by exponential enrichment (SELEX) was used to develop DNA ligands (aptamers) to cholera whole toxin and staphylococcal enterotoxin B (SEB).
John G. Bruno, Johnathan L. Kiel
doaj   +1 more source

DNA aptamer against EV-A71 VP1 protein: selection and application

open access: yesVirology Journal, 2021
Background Enterovirus 71 (EV-A71) is a highly infectious pathogen associated with hand, foot and mouth disease, herpangina, and various neurological complications, so it is important for the early detection and treatment of EV-A71.
Xinran Zou   +4 more
doaj   +1 more source

Discovery of Aptamers and the Acceleration of the Development of Targeting Research in Ophthalmology

open access: yes, 2023
Jiamin Cao, Feng Zhang, Wei Xiong Department of Ophthalmology, Third Xiangya Hospital, Central South University, Changsha, People’s Republic of ChinaCorrespondence: Feng Zhang; Wei Xiong, Department of Ophthalmology, the Third Xiangya Hospital, Central ...
Zhang F, Cao J, Xiong W
core  

The Evolution of Aerosol Jet Printing, A Review: Enhancing Material Versatility and Improvements for Next‐Generation Applications

open access: yesAdvanced Materials Technologies, EarlyView.
Aerosol Jet Printing (AJP) has emerged as a versatile additive manufacturing technique for high‐resolution, conformal, and multi‐material printing. This review highlights advances in printable materials, substrate compatibility, post‐processing, characterization, and process innovations, while critically discussing current challenges and future ...
Chandrachur Chatterjee   +2 more
wiley   +1 more source

Aptamers for proteomics [PDF]

open access: yes, 2008
Changes in post-translation modifications are very important in the regulation of biological processes. Many modifications occur at very low levels, resulting in a low-abundance of the modified proteins in cells, and therefore assessing those ...
Cass, Tony, Le, Thao Thi, Miller, Andrew
core   +2 more sources

Revealing the Transmission Hologram's Refractive Index Profile Stored in a Photohydrogel: A Structural Characterization

open access: yesAdvanced Optical Materials, EarlyView.
A theoretical model is developed to visualize three‐dimensional refractive index profiles in transmission holographic gratings. In this work, it is applied to photopolymerizable hydrogels, enabling detailed analysis of the internal structure of recorded holograms and their evolution under different degradation conditions.
Belén Nieto‐Rodríguez   +4 more
wiley   +1 more source

The minimum aptamer publication standards (MAPS guidelines) for de novo aptamer selection

open access: yes, 2022
Aptamers were first described in 1990 and since then many aptamers have been reported in the literature for numerous applications in both diagnostics and therapeutics.
McKeague, M   +15 more
core  

Time‐Multiplexed Organic Electrochemical Transistor for Saliva‐Based Rapid Detection of Viral Proteins

open access: yesAdvanced Science, EarlyView.
A time‐multiplexed nanobody‐functionalized organic electrochemical transistor enables rapid and sensitive detection of three respiratory viral proteins from saliva. Sequentially addressed multi‐gate electrodes on a shared channel achieve around 1 fm detection within 15 min without sample preprocessing. Clinical validation demonstrates high specificity,
Tianrui Chang   +13 more
wiley   +1 more source

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