Results 91 to 100 of about 83,758 (359)

Prospective validation of podoplanin expression as a diagnostic biomarker of acute promyelocytic leukemia

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Acute promyelocytic leukemia (APL) is a medical emergency that needs immediate diagnosis and treatment. Podoplanin, a transmembrane glycoprotein that binds CLEC‐2 on platelets, was recently demonstrated to be abnormally expressed in leukemic blasts in APL, as opposed to other forms of AML, in a study using thawed primary cells.
Camilla Maria de Alencar Saraiva, Carla Roberta Peachazepi Moraes, Bruno Kosa Lino Duarte, Gislaine Borba Oliveira, Herton Luiz Alves Sales Filho, Paula de Melo Campos, Sara Teresinha Olalla Saad, Erich Vinicius De Paula   +7 more
wiley   +1 more source

Evaluation of the Coagulant Effect of Zanjani and Latifi Viper Snake Venom Endemic in Iran

Trends in Peptide and Protein Sciences, 2016
The venom of the viper is very important in pharmaceutical usage, such as in the process of coagulation during medical care. This study aims to evaluate the coagulant factor of Latifi and Zanjani viper venom.
Milad Taherian, Hajar Yaghoobi, Mojgan Bandehpour   +2 more
doaj   +1 more source

No influence of dabigatran anticoagulation on hemorrhagic transformation in an experimental model of ischemic stroke [PDF]

, 2012
Background: Dabigatran etexilate (DE) is a new oral direct thrombin inhibitor. Clinical trials point towards a favourable risk-to-benefit profile of DE compared to warfarin. In this study, we evaluated whether hemorrhagic transformation (HT) occurs after
Bohmann, Ferdinand, Förch, Christian, Lindhoff-Last, Edelgard, Mirceska, Ana, Pfeilschifter, Josef Martin (Prof. Dr.), Pfeilschifter, Waltraud, Steinmetz, Helmuth   +6 more
core   +3 more sources

Design of a new type of coating for the controlled release of heparin [PDF]

, 1997
Thrombus formation at the surface of blood contacting devices can be prevented by local release of heparin. Preferably, the release rate should be constant for prolonged periods of time.
Engbers, G.H.M., Feijen, J., Hinrichs, W.L.J., Hoopen, H.W.M. ten, Wissink, M.J.B.   +4 more
core   +3 more sources

Prothrombine and activated partial thromboplastin time are prolonged in hepatic cirrhosis

Universa Medicina, 2016
Background Chronic hepatitis and hepatic cirrhosis are chronic liver diseases that cause disorders of liver function, such as the formation of platelets and coagulation factors (prothrombin time/PT and activated partial thromboplastin time/APTT ...
Edward Kurnia Setiawan Limijadi, Lisyani Budi Suromo, Imam Budiwiyono   +2 more
doaj   +1 more source

Hemostatic abnormalities at the time of fetal death: A retrospective study evaluating the prevalence and relevance of targeted testing

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To assess the prevalence of hemostasis abnormalities at the time of fetal death diagnosis. Methods This retrospective single‐center study included all fetal deaths between 22 and 42 weeks from July 2017 to December 2023, excluding multiple pregnancies, patients on anticoagulant therapy, and those with known pre‐existing coagulation ...
Chloé Lieng, Catherine Fischer, Aude Girault   +2 more
wiley   +1 more source

Haemostatic Abnormalities in Patients with Cirrhosis and their Relation with Severity of Liver Dysfunction as Assessed by Child Pugh Score

JLUMHS, 2017
OBJECTIVE: To evaluate the hemostatic abnormalities in patients with cirrhosis and their relation with severity of liver dysfunction as assessed by Child Pugh Score.
Hanozia Hassan, Asmat Kamal Ansari , Salma Farrukh Memon   +2 more
doaj   +1 more source

Catastrophic Gastrointestinal Bleeding: Always Consider Meckel’s Diverticulum

European Journal of Case Reports in Internal Medicine, 2019
Meckel’s diverticulum, a congenital malformation of the gastrointestinal tract, is asymptomatic in the majority of patients but can be associated with some complications.
Filipa Pedro, Joana Romano, Marta Rebelo, Rogério Matias, Eduarda Carmo   +4 more
doaj   +1 more source

The Evaluation of APTT Reagents in Reference Plasma, Recombinant FVIII Products; Kovaltry® and Jivi® Using CWA, Including sTF/7FIX Assay [PDF]

, 2021
Hideo Wada, Katsuya Shiraki, Takeshi Matsumoto, Kohshi Ohishi, Hideto Shimpo, Yumi Sakano, Hiroko Nishii, Motomu Shimaoka   +7 more
openalex   +1 more source

Construction and Validation of a Preoperative Surgical Difficulty Prediction and Risk Stratification System for Posterior Spinal Deformity Correction Surgery Based on Machine Learning ‐ Multicenter Cohort Study

iMetaMed, EarlyView.
A web calculator, trained on multicenter data with seven Boruta‐selected preoperative features, predicts prolonged operative time for posterior spinal deformity correction to enable individualized planning and optimized operating‐room resources. ABSTRACT Operative duration reflects surgical complexity and is valuable for perioperative planning.
Chan Xu, Jialiang Zheng, Chengliang Yin, Runmin Li, Xubin Quan, Binghao Chen, Zhaohui Hu, Tongqing Luo, Hao Jiang, Xuewen Hou, Qizhong Xu, Weiheng He, Liang Chen, Anfa Chen, Xin Zhou, Wei Huang, Sen Gao, Jiali Yu, Zhi‐Ri Tang, Yusi Zhang, Kai Wang, Shi‐Nan Wu, Wencai Liu, Xiangdong Xi, Haizhen Ding, Qiang Liu, Haopeng Luan, Wenle Li   +27 more
wiley   +1 more source