Results 91 to 100 of about 796 (185)

The use of QbD for the development and validation of a stability-indicating RP-HPLC method for the quantitation of nevirapine in bulk, tablet and niosome formulations

Frontiers in Analytical Science
IntroductionA reversed-phase high-performance liquid chromatographic (RP-HPLC) method was developed and validated for the quantitation of nevirapine (NVP) in bulk drug, commercial tablets, and niosome formulations using an Analytical Quality by Design ...
Bwalya A. Witika, Roderick B. Walker
doaj   +1 more source

Model inversion and three-way decompositions in the analytical quality by design strategy for the determination of phthalates BY HS-SPME-GC-MS [PDF]

In this work, strategies within Analytical Quality by Design (AQbD) with tools of the Process Analytical Technology (PAT) were used in the development of a head space-solid phase microextraction-gas chromatography-mass spectrometry (HS-SPME-GC-MS ...
Herrero Gutiérrez, Ana, Ortiz Fernández, Mª Cruz, Reguera Alonso, Celia, Sarabia Peinador, Luis Antonio, Sánchez Pastor, Mª Sagrario, Valverde Som, Lucía   +5 more
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IMPLEMENTING OF ANALYTICAL QUALITY BY DESIGN FOR HIGH QUALITY PHARMACEUTICAL PRODUCTS [PDF]

The quality in the pharmaceutical industry has become a very important topic. Pharmaceutical industry has been emerging rapidly for the last decade by focusing on product Quality, Safety, and Efficacy.
P. Abhinandana1.2*, Ramarao Nadendla2
core   +1 more source

OPTIMASI DAN VALIDASI METODE KLT-DENSITOMETRI PADA ANALISIS FARMASI : TINJAUAN KRITIS DAN STUDI KOMPARATIF [PDF]

Kromatografi Lapis Tipis (KLT) Densitometri atau High Performance Thin Layer Chromatography (HPTLC) tetap menjadi metode analisis instrumental yang vital, terutama di negara berkembang, karena efisiensi biaya dan kemampuannya menangani banyak sampel ...
Anggrainy, Dian Sari, Chantika, Shelfia Putri, Fadhilah, Fauzi Rizki, Marfanie, Auryn Difani, Nugraha, Nadia Afianti, Putra, Muqsidana Sayidina Gara, Sinaga, Jessica Putri   +6 more
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Quality Improvement with Scientific Approaches (QbD, AQbD and PAT) in Generic Drug Substance Development: Review

International Journal of Research and Development in Pharmacy & Life Science, 2015
Drug substance synthesis requires strong chemistry knowledge and innovative thinking to publish and challenge patents. Creative synthetic route supports to have critical patent claims and challenges the entry of generic players in the market. Since innovators are covering many parameters like stereo selective (isomerism), polymorphic (crystallinity ...
Raman VVSSN, Useni Reddy M
openaire   +1 more source

Environmentally sustainable analytical quality by design aided RP-HPLC method for the estimation of brilliant blue in commercial food samples employing a green-ultrasound-assisted extraction technique

Green Processing and Synthesis, 2023
Chakraborty Atyurmila, Jayaseelan Kavitha   +1 more
doaj   +1 more source

Analytical Quality by Design (AQbD) Approach to the Development of In Vitro Release Test for Topical Hydrogel [PDF]

, 2022
Berkó Szilvia, Budai-Szűcs Mária, Csányi Erzsébet, Kovács Anita, Pannonhalminé Csóka Ildikó, Szoleczky Réka, Tonka-Nagy Péter   +6 more
core   +1 more source

AQbD-Driven Method Development for Magnetic Nanoparticle Extraction and HPLC Analysis: A Comprehensive Review

Asian Journal of Chemistry
The integration of analytical quality by design (AQbD) principles into analytical method development has revolutionized precision, robustness and regulatory compliance in the pharmaceutical and environmental sciences. This review explores the AQbD-driven optimization of magnetic nanoparticle (MNP) extraction coupled with high-performance liquid ...
Raneem Darraj, Mohammad Haroun, Ayat Abbod, Ibrahim Alghoraibi   +3 more
openaire   +1 more source

A comprehensive RP-HPLC technique for analyzing disodium edetate and its degradation products in eye drops using AQbD and Six Sigma perspective

Reviews in Analytical Chemistry
The study presents the development of a novel, sustainable, and analytical quality by design (AQbD) driven RP-HPLC method to simultaneously identify disodium edetate in eye drops and its degradation products.
Alanazi Tahani Y. A., Alluhayb Abdullah H., Alsehli Bandar R., Binsaleh Ammena Y., Saleh Sayed M., Mohamed Mahmoud A.   +5 more
doaj   +1 more source

Integrated Application of Risk Management Techniques in Developing an Analysis Method for Traditional Chinese Medicine: A Case Study of a Percolation Solution for Xiaochaihu Capsules

Chemosensors
Risk management should run through the entire process of method development, utilization, and maintenance. Based on the analytical quality by design (AQbD) concept, various integrated risk management techniques were used in this study to develop an ...
Mintong Zhao, Yanni Tai, Gelin Wu, Feng Ding, Haibin Qu, Xingchu Gong   +5 more
doaj   +1 more source