Results 101 to 110 of about 796 (185)

Analytical Quality by Design (AQbD) for Quality and Risk Assessment of Pharmaceuticals to Immunomarkers

Journal of Pharmaceutical and Biopharmaceutical Research
Using advanced scientific and risk-based approaches for analytical methods offers significant benefits. Quality by Design (QbD) is a systematic framework that emphasizes understanding and controlling both product and process elements. Adhering to the principles outlined in the ICH guidelines can considerably improve the quality of drug substances ...
Vivekanandan Kalaiselvan, Meenakshi Dahiya, Gaurav Sanjay Mahalpure, Ritu Tiwari   +3 more
openaire   +1 more source

RP-HPLC method development and validation of Abacavir, Lamivudine and Zidovudine in combined pharmaceutical dosage by analytical QbD

Discover Chemistry
An accurate, precise, robust, and green RP-HPLC method was developed for assessment of three antiviral medications, namely Abacavir (ABA), Lamivudine (LAMI), and Zidovudine (ZIDO) in combined pharmaceutical dosage form by Analytical Quality by Design ...
Divyesh Vanparia, Ronak R. Dedania, Zarna R. Dedania   +2 more
doaj   +1 more source

Application of Qbd Principles to Develop and Validate a Method for Cinacalcet Determination in Api and Its Dosage Form [PDF]

Introduction: Cinacalcet Hcl [CIN] is used to treat hyperthyroidism and hypercalcisim. and improves the sensitivity of calcium receptors on parathyroid cells to reduce parathyroid harmone levels and hence decrease serum calcium levels. It also has a role
A.Srinija, Sneha Takur, R.Prasanthi, Buggana Siva Jyothi, R.Swetha Sri
core   +2 more sources

Development of a quality by design based eco-friendly RP-HPLC method for Ticagrelor and Aspirin

Green Analytical Chemistry
Background: Ticagrelor (TICA) and Aspirin (ASP) are widely prevalent antiplatelet drugs. With growing focus on sustainable operations, there is a necessity for green and strong analytical procedures for their simultaneous estimation. Objective: To design
Shivani Jani, Ujashkumar Shah, Jayvadan Patel, Monika Dua   +3 more
doaj   +1 more source

Implementation of quality by design and green chemistry principles to validate the stability indicating method on UHPLC for the simultaneous quantification of Glycopyrronium, Fluticasone, Vilanterol in inhaled formulation

Green Analytical Chemistry
The combination of Glycopyrronium, Fluticasone, and Vilanterol is utilized to manage chronic obstructive pulmonary disease (COPD) and mitigate asthma symptoms.
Anitha L, Durga Prasad Beda
doaj   +1 more source

A sustainable RP-HPLC method for simultaneously estimating aceclofenac, paracetamol, and serratiopeptidase with AQbD optimization

Green Analytical Chemistry
This study focused on developing and validating a novel method for the simultaneous estimation of aceclofenac (AFC), paracetamol (PCM), and serratiopeptidase (SPD) using reverse phase high-performance liquid chromatography (RP-HPLC). The method was designed based on Analytical Quality by Design principles, incorporating green and white analytical ...
Vineetha Rosireddy, Manikandan Krishnan
openaire   +2 more sources

Application of the quality by design (QbD) approach to the development and validation of analytical methods for the quantification of Lumateperone Tosylate as the bulk drug and capsule dosage form by HPLC

Future Journal of Pharmaceutical Sciences
Background The current studies involve the development of a liquid chromatographic method that is highly effective (HPLC) for the Lumateperone Tosylate method that is simple, rapid, accurate, precise, and economical, all made possible by analytical ...
Vasudha S. Bavadekar, Angha M. Joshi, Ujwala S. Desai   +2 more
doaj   +1 more source

Quality assessment, HPTLC-DPPH, analytical quality by design based HPTLC method development for estimation of piperine in piper species and marketed formulations

Green Analytical Chemistry
Background: Quality assessment of herbs is an essential aspect. In this study HPTLC method is developed by employing the quality based optimization approach with the aid of analytical quality by design tools and the quality assessment of the Piper ...
Amruta Balekundri, Pramod J Hurkadale, Harsha Hegde   +2 more
doaj   +1 more source

An Ecologically Sound RP-HPLC Method for Estimating Citicoline using AQbD with Degradation Studies

INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY
Background: Citicoline is widely used for neurological complications. This research work was carried out using reverse-phase high-performance liquid chromatography (RP-HPLC) employing green analytical chemistry principles. Materials and Methods: The method was completely developed with ethanol:water (20:80 v/v) as the mobile phase, 0.1% orthophosphoric
Manikandan Krishnan, R Vineetha
openaire   +1 more source

Advancing relugolix analysis: A comparative study and AQbD-driven method optimization with stability testing

Journal of Applied Pharmaceutical Science
The current study aimed to develop a novel liquid chromatographic method based on analytical quality by design to analyze relugolix and its related substances. This study builds upon a comparative review of existing analytical methods, highlighting the absence of a pharmacopoeial standard for relugolix determination.
Priyanka Nagar, Arvind Kumar Sharma, Robin Kumar, Chhaya Chauhan, Rini Singhal, Minakshi Garg   +5 more
openaire   +1 more source