Results 81 to 90 of about 796 (185)

Development and Validation of a Novel Isocratic RP-HPLC Method Using AQbD Approach for the Quantification of Favipiravir [PDF]

Background/Objectives: In this study, the analytical quality by design (AQbD) approach was used to develop an eco-friendly reversed-phase high-performance liquid chromatography (RP–HPLC) method to identify and quantify favipiravir (FAV).
Balogh György Tibor, Katona Gábor, Pannonhalminé Csóka Ildikó, Salamah Maryana, Sipos Bence, Volk Balázs   +5 more
core   +1 more source

AQBD ASSISTED SPECTROPHOTOMETRIC METHODS FOR THE QUANTIFICATION OF CEFIXIME TRIHYDRATE USING TWO OXIDATIVE COUPLING AGENTS

Asian Journal of Pharmaceutical and Clinical Research, 2019
Objective: The present study focuses on developing two visible spectrophotometric methods for cefixime trihydrate (CFT) by the utilization of analytical quality by design space concept. The critical method variables were screened and optimized by factorial design.
null KOKILAMBIGAI K S, null LAKSHMI K S
openaire   +2 more sources

Implementation of Quality by Design (QbD) approach to the analytical method development and validation for the estimation of Remogliflozin Etabonate in tablet dosage form by HPLC [PDF]

Analytical Quality by Design is a recent concept related to the development and validation of the analytical procedures (AQbD). This is done in analytical QbD by defining quality targets which enable the performance of the analytical procedure within the
Yash M. Phulwani, Shankar S. Yelmame, Laxmikant B. Borse
core   +2 more sources

Analytical quality by design (AQbD) assisted RP-HPLC technique for quantification of Picroside II in bulk and pharmaceutical dosage form

Future Journal of Pharmaceutical Sciences
Background Quality by design (QbD) adverts toward gaining of few expected quality with predetermined and desired specifications. Analytical quality by design (AQbD) approach toward the development of analytical method can significantly lead toward the ...
Sharib Raza Khan, Shailesh Dadge, Shivam Rathaur, Jiaur R. Gayen   +3 more
doaj   +1 more source

Analytical Quality by Design approach in the development of a green reversed-phase ultra-high performance liquid chromatography/high-resolution time-of-flight mass spectrometry method for the simultaneous analysis of synthetic antimicrobial and hypotensive peptides

Journal of Chromatography Open
The growing therapeutic interest in peptides from Tityus stigmurus scorpion venom and their analogues highlights the need for the development of robust analytical methods for these compounds.
Ana Roberta Pereira Johnson dos Anjos, Márcia Natália da Silveira Pinto, Dayanne Lopes Porto, Fabio Santos de Souza, Rui Oliveira Macedo, Matheus de Freitas Fernandes Pedrosa, Cícero Flávio Soares Aragão   +6 more
doaj   +1 more source

OPTIMIZING RP-HPLC TECHNIQUES FOR RELIABLE ANALYSIS OF DIABETES MEDICATIONS [PDF]

Introduction: A robust and precise RP-HPLC method was developed for the simultaneous quantification of Metformin, Vildagliptin, and Remogliflozin in pharmaceutical formulations, essential for managing Type 2 Diabetes Mellitus (T2DM).
Venkata sai suresh kumar sista* , Anjali jha, V LNSH Hari Haran. A, R S K Sharma , Anindita Chatterjee, G V Siva Prasad, K. Satyam Naidu, R. Sarada
core   +2 more sources

A-QbD-based green RP-HPLC method for estimation of rivaroxaban in pharmaceutical dosage forms

Discover Chemistry
This work reports the Analytical Quality by Design (AQbD) based green RP-HPLC method for Rivaroxaban, aimed at delivering a sustainable and robust analytical approach.
Yukta Vijay Kotecha, Dinesh Dattatray Rishipathak, Rakesh Uttamrao Shelke, Vijay Arjun Bagul, Anand Radheshyam Tiwari, Suryakant D. Bhosle   +5 more
doaj   +1 more source

Central composite design (CCD) approach to develop HPLC method for caffeine: Application to coffee samples analysis of Jazan region, Saudi Arabia

Journal of Saudi Chemical Society
The goal of this study was to use High performance liquid chromatography (HPLC) with an Analytical Quality by Design (AQbD) approach to measure the amount of caffeine in selected coffee samples available in the local Jazan market in Saudi Arabia.
Asim Najmi, Zia ur Rehman, Khalid Zoghebi, Hassan Ahmed Alhazmi, Mohammed Mofarreh Albratty, Qasem Yahya Hassan Haroobi, Ismail Mohammed Ali Sayram, Mohammed Ahmed Saleh, Waleed Mohammed Ahmed Qaser, Abdulaziz Ali Houssein Qaysi   +9 more
doaj   +1 more source

Development and Validation of a Stability Indicating Analytical Method for the Estimation of Gliclazide and Sitagliptin in Bulk Drugs and Tablet Dosage Forms by RP-UPLC: An Application of the Quality-by-Design Approach [PDF]

Sitagliptin and gliclazide are the active ingredients in OpdualagTM. A highly selective DPP-4 inhibitor, sitagliptin is thought to work in type 2 diabetics by delaying the inactivation of incretin hormones, which increases their concentration and ...
Nunsavathu, Sambasiva Naik, Rajaganapathy, Dr. K.   +1 more
core   +2 more sources

Analytical quality by design (AQbD) based optimization of RP-UPLC method for determination of nivolumab and relatlimab in bulk and pharmaceutical dosage forms

Future Journal of Pharmaceutical Sciences
Background The Analytical Quality by Design (AQbD) methodology extends the application of Quality by Design (QbD) principles to the management of the analytical procedure life cycle, encompassing method creation, optimization, validation, and continuous ...
Mohana Vamsi Nuli, Ramanjaneyulu Seemaladinne, Anil Kumar Tallam   +2 more
doaj   +1 more source