Relationship of expression of aquaglyceroporin 9 with arsenic uptake and sensitivity in leukemia cells [PDF]
, 2007 Arsenic trioxide (As 2O 3) is highly efficacious in acute promyelocytic leukemia (APL). Aquaglyceroporin 9 (AQP9) is a transmembrane protein that may be involved in arsenic uptake.
Leung, J +4 more
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PREPARATIVE SCALE PRODUCTION AND FUNCTIONAL RECONSTITUTION OF A HUMAN AQUAGLYCEROPORIN (AQP3) USING A CELL-FREE EXPRESSION SYSTEM [PDF]
, 2011 Understanding the selectivity of aquaporin (AQP) membrane channels will require structural and functional studies of wild type and modified proteins; however, expression systems have not previously yielded AQPs in the necessary milligrams quantities ...
PELLEGRINI CALACE M +8 more
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Pentamidine Is Not a Permeant but a Nanomolar Inhibitor of the Trypanosoma brucei Aquaglyceroporin-2 [PDF]
, 2016 The chemotherapeutic arsenal against human African trypanosomiasis, sleeping sickness, is limited and can cause severe, often fatal, side effects. One of the classic and most widely used drugs is pentamidine, an aromatic diamidine compound introduced in ...
Rothert, Monja +20 more
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Environmental Health, 2017 Background Sex-specific factors play a major role in human health and disease, including responses to environmental stresses such as toxicant exposure. Increasing evidence suggests that such sex differences also exist during fetal development.
Emily F. Winterbottom +7 more
doaj +1 more source
Can aquaporins be used as diagnostic and prognostic markers for uterine smooth muscle tumours?
Biotechnology & Biotechnological Equipment, 2017 Generally, uterine leiomyosarcoma is easily diagnosed. However, uterine smooth muscle tumours which show atypical histological features and unusual growth patterns may mimic malignancy and may not be easily diagnosed.
Ulaş Alabalık +6 more
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Improvement of acetic acid tolerance and fermentation performance of Saccharomyces cerevisiae by disruption of the FPS1 aquaglyceroporin [PDF]
, 2020 The FPS1 gene coding for the Fps1p aquaglyceroporin protein of an industrial strain of Saccharomyces cerevisiae was disrupted by inserting CUP1 gene.
Na Guo +6 more
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The pursuit of membrane protein structures and the malarial aquaglyceroporin pfAQP [PDF]
, 2008 When I began my thesis work, structures of membrane proteins were few and far between. It was clear that the field was poised for a growth period and offered myriad opportunities for pursuing targets involved in important and interesting biology.
Newby, Zachary Eric Robert
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ATP-binding cassette transporters and drug resistance in cutaneous leishmaniasis
International Journal of Infectious DiseasesLeishmania spp. are intracellular protozoan parasites causative of visceral and cutaneous leishmaniasis. Recognized as a neglected tropical disease affecting millions of people around the world, this affliction represents a major public health problem ...
Marina B.R. de Santana +2 more
doaj +1 more source
AQP3 is regulated by PPARγ and JNK in hepatic stellate cells carrying PNPLA3 I148M
Scientific Reports, 2017 Aquaglyceroporins (AQPs) allow the movement of glycerol that is required for triglyceride formation in hepatic stellate cells (HSC), as key cellular source of fibrogenesis in the liver.
Matteo Tardelli +8 more
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BMC BiologyBackground Extremophiles evolved capacities to survive extended exposure to harsh environmental conditions such as complete desiccation (anhydrobiosis) and freezing (cryobiosis).
Ángel Rey-Alfonso +7 more
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