A practical guide for rapid disease modifying therapy initiation and maintenance in aquaporin-4 positive neuromyelitis optica. [PDF]
S G, Pm N, S Y, S B.
europepmc +1 more source
Ischemia–Reperfusion Injury: Molecular Mechanisms and Therapeutic Interventions
Multiorgan ischemia–reperfusion injury begins with ischemia‐induced ATP depletion and ionic imbalance, followed by reperfusion‐triggered mitochondrial ROS/RNS bursts, regulated cell death, and DAMP release. Sterile inflammation converges on endothelial–immune–coagulation crosstalk, where NETs drive immunothrombosis, no‐reflow, and remote organ injury ...
Peng An +4 more
wiley +1 more source
Are diurnal variations in glymphatic clearance driven by circadian regulation of Aquaporin-4 expression? [PDF]
Frey MM +4 more
europepmc +1 more source
Magnetic Resonance Imaging at 14 Tesla of Prostate Biopsies Obtained after Prostatectomy
Fresh prostate biopsies were imaged using a 14 T vertical bore MRI scanner, and the effects of long gradient separation Δ (10–400 ms) were explored. At Δ longer than 10 ms, the percentage of voxels where the Akaike information criteria (AICc) favored a monoexponential model increased, and the apparent diffusion coefficient (ADC) lowered compared to Δ ...
Fredrik Langkilde +4 more
wiley +1 more source
The Fluidic Connectome in Brain Disease: Integrating Aquaporin-4 Polarity with Multisystem Pathways in Neurodegeneration. [PDF]
Brehar FM +6 more
europepmc +1 more source
Redox signals and oxidative stress in the control of mitochondrial protein import
Abstract Mitochondrial protein import is essential for organelle biogenesis and cellular homeostasis. It operates in an environment that is intrinsically shaped by redox chemistry. Mitochondria are major sources of reactive oxygen species (ROS), which arise as by‐products of oxidative phosphorylation. Cells therefore maintain sophisticated ROS‐handling
Lidwina Hasberg +3 more
wiley +1 more source
Changes in Blood Cells and Complements During Relapse Prevention Therapies for Aquaporin-4 Antibody-Positive Neuromyelitis Optica Spectrum Disorder. [PDF]
Kuroda H +15 more
europepmc +1 more source
Summary An uncommon complication following prosthetic laryngoplasty was reported in a 4‐year‐old Andalusian mare. The mare was presented with a previously diagnosed left‐sided recurrent laryngeal neuropathy, after initial evaluation the mare underwent ventriculocordectomy and prosthetic laryngoplasty.
J. L. Sanclemente +2 more
wiley +1 more source
The Glymphatic-Venous Axis in Brain Clearance Failure: Aquaporin-4 Dysfunction, Biomarker Imaging, and Precision Therapeutic Frontiers. [PDF]
Costea D +7 more
europepmc +1 more source

