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Aquaporin-4, homeostasis, and neurologic disease
Neurology, 2007Aquaporins constitute a family of water channels that regulate the transport of water in essentially all organs, including the kidney, gastrointestinal tract, secretory glands, inner ear, nervous system, and muscle.1–3 Because of his seminal discovery of aquaporins as the long-sought water channels,1 Peter Agre of Johns Hopkins University was awarded ...
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Aquaporin 4: A key player in Parkinson's disease
Journal of Cellular Physiology, 2019Parkinson's disease (PD) is one of the most prevalent neurodegenerative diseases which occur in aged people worldwide. Given that a sequence of cellular and molecular mechanisms, including oxidative stresses, apoptosis, inflammatory pathways, microglia ...
O. Tamtaji +4 more
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Heterotetrameric Composition of Aquaporin-4 Water Channels
Biochemistry, 1999Aquaporin (AQP) water channel proteins are tetrameric assemblies of individually active approximately 30 kDa subunits. AQP4 is the predominant water channel protein in brain, but immunoblotting of native tissues has previously yielded multiple poorly resolved bands.
Agre, Peter +3 more
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Journal of Neurosurgery: Pediatrics, 2006
James P. McAllister, Janet M Miller
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James P. McAllister, Janet M Miller
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Neuropathology and Applied Neurobiology, 2018
Per Kristian Eide +2 more
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Per Kristian Eide +2 more
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