Results 251 to 260 of about 69,793 (345)

Human Brain Vasculature‐on‐a‐Chip Model Constructed With Microvessels Isolated From Cryopreserved Postmortem Human Brain Tissue

Advanced Healthcare Materials, Volume 15, Issue 13, 3 April 2026.
This manuscript describes the cultivation of viable microvessels from cryopreserved human brain tissue. When embedded in hydrogels and cultured in microfluidic devices, these microvessels exhibit complex architectures reminiscent of arterioles and capillaries, can be perfused, and display intact barrier function. Collectively, these results demonstrate
Brian J. O'Grady, A. Scott McCall, Samuel Cullison, Daniel Chavarria, Matthew S. Schrag, Ethan S. Lippmann   +5 more
wiley   +1 more source

Peran Melatonin pada ekspresi Malondialdehyde (MDA) dan Myeloperoksidase (MPO) Sel Mikroglia serta Aquaporin-4 (AQP4) dan Vascular Endothelial Growth Factor (VEGF) Sawar Darah Otak Tikus pascacedera Kepala

, 2014
Khairul Ihsan Nasution
openalex   +1 more source

Rituximab as First‐Line Compared to Escalation Immunotherapy Is Associated With Lower Disability Accumulation in Aquaporin‐4‐IgG‐Positive Neuromyelitis Optica Spectrum Disorder: A Multicenter Cohort Study From Germany and the United Kingdom [PDF]

Daniel Engels, Chiara Rocchi, Mirasol Forcadela, Pakeeran Siriratnam, Marius Ringelstein, Martin W. Hümmert, Katrin Giglhuber, Achim Berthele, Corinna Trebst, Orhan Aktas, Joachim Havla, Saif Huda, Tania Kümpfel   +12 more
openalex   +1 more source

Are diurnal variations in glymphatic clearance driven by circadian regulation of Aquaporin-4 expression? [PDF]

Fluids Barriers CNS
Frey MM, Zohoorian N, Skauli N, Ottersen OP, Amiry-Moghaddam M.   +4 more
europepmc   +1 more source

Astrocyte Enrichment of 3D Cortical Constructs Enhances Brain Repair

Advanced Science, Volume 13, Issue 20, 9 April 2026.
This study highlights the role of astrocytes in supporting neural progenitor cell survival and differentiation after traumatic brain injury. Astrocytes enhanced neuronal differentiation, improved cell survival in co‐cultures, and promoted integration of microfluidics‐based implants with host tissue following implantation. Additionally, increased axonal
Elisa M. Cruz, Luana C. Soares, Gretchen Greene, Fernando Messore, Mohammed Abuelem, Mingyu Li, Caroline Andersen, Mirriam Domocos, Elisa Vitiello, Rabeah Abdul Razak, Marlene Lawston, Gabriel Moser, Talia Vasaturo‐Kolodner, Mona Barkat, Roslyn M. Bill, Edward Mann, Linna Zhou, Mootaz M. Salman, Hagan Bayley, Zoltán Molnár, Francis G. Szele   +20 more
wiley   +1 more source

Changes in Blood Cells and Complements During Relapse Prevention Therapies for Aquaporin-4 Antibody-Positive Neuromyelitis Optica Spectrum Disorder. [PDF]

Int J Mol Sci
Kuroda H, Fujihara K, Kaneko K, Takai Y, Matsumoto Y, Otomo M, Yamazaki N, Umezawa S, Yamamoto N, Sakamoto N, Namatame C, Ono H, Nishiyama S, Takahashi T, Misu T, Aoki M.   +15 more
europepmc   +1 more source

Use of anti–amyloid‐β monoclonal antibodies in persons with Down syndrome Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 4, April 2026.
Abstract INTRODUCTION The recent development and licensing of anti–amyloid‐β monoclonal antibodies for the treatment of early‐stage Alzheimer's disease have significantly shifted the clinical landscape. However, current use recommendations preclude the administration of these new drugs to persons who have Down syndrome.
Clíona Farrell, Fedal Saini, Mona M. Beidas, Natalie S. Ryan, Andre Strydom, Frances K. Wiseman   +5 more
wiley   +1 more source

Anti-Aquaporin-4 Antibody-Seronegative NMO Spectrum Disorder with Baló's Concentric Lesions

, 2013
Hiroki Masuda, Masahiro Mori, Kaoru Katayama, Yuriko Kikkawa, Satoshi Kuwabara   +4 more
openalex   +2 more sources

The Glymphatic-Venous Axis in Brain Clearance Failure: Aquaporin-4 Dysfunction, Biomarker Imaging, and Precision Therapeutic Frontiers. [PDF]

Int J Mol Sci
Costea D, Dobrin N, Tataru CI, Toader C, Șerban M, Covache-Busuioc RA, Munteanu O, Diaconescu IB.   +7 more
europepmc   +1 more source

Genetic correlation analysis of Alzheimer's disease and stroke implicates PHLPP1 as a shared locus in individuals of African ancestry

Alzheimer's &Dementia, Volume 22, Issue 4, April 2026.
Abstract INTRODUCTION Neuropathological studies indicate a strong association between Alzheimer's disease (AD) and stroke, yet the molecular mechanisms underlying this association remain unclear. METHODS Local genetic correlation analysis was conducted with LAVA (Local Analysis of [co]Variant Annotation) using the results from genome‐wide association ...
Nicholas R. Ray, Jiji Kurup, Ajneesh Kumar, Farid Rajabli, Liyong Wang, Wanying Xu, Fulai Jin, Elanur Yilmaz, Caghan Kizil, Luciana Bertholim‐Nasciben, Sofia Moura, Aura M. Ramirez, Olusegun Baiyewu, Anthony J. Griswold, Motunrayo Coker, Kyle M. Scott, Kazeem Akinwande, Larry D. Adams, Samuel Diala, Patrice G. Whitehead, Jacob L. McCauley, Mayowa Ogunronbi, Kara L. Hamilton‐Nelson, Albertino Damasceno, Andrew F. Zaman, Susan H. Blanton, Albert Akpalu, Michael L. Cuccaro, Kolawole Wahab, Katalina F. McInerney, Karen Nuytemans, Reginald Obiako, Pedro R. Mena, Njideka Okubadejo, Izri M. Martinez, Yared Z. Zewde, Seid A. Gugssa, Fred S. Sarfo, Raj Kalaria, David M. Ndetei, Scott M. Williams, Allison Caban‐Holt, ADGC, AfDC, Giuseppe Tosto, Jonathan L. Haines, Rufus O. Akinyemi, Adesola Ogunniyi, Goldie S. Byrd, William S. Bush, Brian W. Kunkle, Jeffery M. Vance, Margaret A. Pericak‐Vance, Christiane Reitz   +53 more
wiley   +1 more source