Results 261 to 270 of about 69,793 (345)

Aquaporin-4 deficiency induced white matter injury via upregulated complement component 3 in cerebral small vessel disease. [PDF]

J Neuroinflammation
Chen Y, Jiang L, Yao D, Liu D, Pan Y, Wang Y.   +5 more
europepmc   +1 more source

Sleep‐Dependent Clearance of Brain Metabolites via the Glymphatic System: Implications for Alzheimer's Pathophysiology

Brain and Behavior, Volume 16, Issue 4, April 2026.
Slow‐wave sleep promotes glymphatic transport through coordinated norepinephrine dynamics, vasomotion, and polarized AQP4‐dependent fluid exchange, thereby facilitating clearance of amyloid‐beta and tau. In contrast, sleep disruption, aging, vascular dysfunction, and AQP4 abnormalities impair this system and may accelerate Alzheimer‐related pathology ...
Farshad Zare, Gulnora Shakhmurova, Jasur Rizaev, Aseel Smerat, Rosull Saadoon Abbood, Vinay Patil, Manoj Kumar‐Mishra   +6 more
wiley   +1 more source

Aquaporin-4 triggers inflammation in a murine endotoxin-induced uveitis (EIU) model. [PDF]

BMC Ophthalmol
Wang Q, Gong Y, Ma X, Fu X, Li R, Qiu K, Wang Y, Zhao Q, Li L, Huang Q, Gao L, Hu X, Zhou X, Zhong J.   +13 more
europepmc   +1 more source

Causal Exposures of Immune Cells in Neuromyelitis Optica Spectrum Disorders: A Mendelian Randomization Study and Flow Cytometry Analysis

Brain and Behavior, Volume 16, Issue 4, April 2026.
This study used two‐sample Mendelian randomization to assess causal relationship of immune cells with NMOSD. We then enrolled 27 NMOSD patients and 17 healthy controls for peripheral blood flow cytometric analyses to validate part of MR findings. ABSTRACT Background Neuromyelitis optica spectrum disorders (NMOSD) are an immune‐mediated inflammatory ...
Jingru Ren, Jianchun Wang, Zhenyu Niu, Jing Guo, Nan Zhang, Hongjun Hao, Feng Gao, Ran Liu, Zhaoxia Wang   +8 more
wiley   +1 more source

Anterograde and trans-synaptic neurodegeneration in aquaporin-4-antibody neuromyelitis optica spectrum disorder patients with a history of transverse myelitis. [PDF]

Brain Commun
Jakuszyk P, Szukało P, Kossowski B, Juryńczyk M.   +3 more
europepmc   +1 more source

Status Epilepticus as a Novel Late Complication in CARASIL: A Case Report Expanding the Clinical Spectrum

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT CARASIL may present without systemic features, and seizures including status epilepticus can occur as late‐stage complications. Long‐term neurological monitoring is essential even in patients lacking extra‐neurological manifestations.
Mohammad Amin Najafi, Seyyed Ali Alaei, Alireza Anjam Majoumerd, Seyyed AmirHossein Mirghanizadeh Bafghi, Mahdi Vajdi, Mohammad Reza Najafi   +5 more
wiley   +1 more source

Optical coherence tomography angiography in identifying aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder. [PDF]

BMC Ophthalmol
Dong J, Wang X, Xue H, Zeng Y, Gong H, Li J.   +5 more
europepmc   +1 more source

Pathological Roles of Astrocytes in Traumatic Brain Injury

CNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.
TBI induces intrinsic astrocytic changes, including reactive astrogliosis, A1 and A2 polarization, ion channels activation, pathological edema, oxidative stress, and metabolic dysregulation. These injury‐responsive astrocytes regulate neuroinflammation and tissue remodeling through dynamic crosstalk with microglia, macrophages, vascular endothelial ...
Di Wu, Yuxiao Ma, Baofeng Wang, Yongtao Zheng, Jie Ren, Qingfang Sun, Liuguan Bian, Yuhao Sun   +7 more
wiley   +1 more source

Aquaporin-4-positive neuromyelitis optica in a male Caucasian patient: A rare demographic presentation. [PDF]

SAGE Open Med Case Rep
Ghosh M, Baxter N, Homer-Ward M.
europepmc   +1 more source