Results 271 to 280 of about 69,793 (345)

Astrocyte‐Derived Exosomal miR‐211‐5p Alleviates Blood–Brain Barrier Injury in a Rat Model of Traumatic Brain Injury

CNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.
Astrocyte‐derived exosomes enriched with miR‐211‐5p significantly improved neurological and cognitive outcomes after traumatic brain injury in rats. Treatment reduced astrocyte activation, neuroinflammation, brain edema, and MMP9/AQP4 expression while preserving blood–brain barrier integrity.
Yan Chen, Xuan Yin, Erwei Zhang, Bin Li, Huijie Yu, Jiawang Qi, Minghao Liu, Meng Wang, Zhenzeng Fan, Lijun Yang   +9 more
wiley   +1 more source

Aquaporin-4 as a cerebrospinal fluid biomarker of Alzheimer's disease. [PDF]

Transl Neurodegener
Gómez de San José N, Halbgebauer S, Steinacker P, Anderl-Straub S, Abu-Rumeileh S, Barba L, Oeckl P, Bellomo G, Gaetani L, Toja A, Mravinacová S, Bergström S, Månberg A, Grassini A, Rainero I, Nilsson P, Parnetti L, Otto M.   +17 more
europepmc   +1 more source

Electroacupuncture Modulates Multiple Pathways for Neuroprotection and Neurorepair in Ischemic Stroke

CNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.
EA exerts therapeutic effects in ischemic stroke through multiple mechanisms: it alleviates acute injury by suppressing neuroinflammation, excitotoxicity, oxidative stress, apoptosis, pyroptosis, ferroptosis, autophagy dysregulation, and blood–brain barrier disruption, while enhancing cerebral blood flow, angiogenesis, and neurogenesis to support ...
Mingyue Zhao, Hangyu Shen, Xu Yan, Xiang Gao, Yuchun Liu, Shengjun Zhou, Jingxian Sun, Jie Sun, Yi Huang   +8 more
wiley   +1 more source

Aquaporin 4 knockdown alleviates traumatic brain edema and reduces neuronal axonal growth cone collapse via the RhoA/ROCK pathway

Jiaxu Fang, Xueying Pan, Juan Chen, Xiaohong Yang, Zhihao Wu, Zhuopeng Ying, Yuefu Zhan, Ying Guan, Jianqiang Chen   +8 more
openalex   +1 more source

The potential roles of aquaporin 4 in malignant gliomas

, 2017
Yu‐Long Lan, Xun Wang, Jiacheng Lou, Xiaochi Ma, Bo Zhang   +4 more
openalex   +2 more sources

Deciphering aquaporin-4's influence on perivascular diffusion indices using DTI in rat stroke studies. [PDF]

Front Neurosci
Tian J, Zhang Y, Liu L, Li C, Hao X.
europepmc   +1 more source

Inhibition of Transglutaminase 2 Preserves Blood–Brain Barrier Integrity and Improves Neurological Outcomes After Experimental Traumatic Brain Injury in Mice

CNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.
The article unraveled that inhibition or knockdown of TGM2 can restore blood–brain barrier (BBB) permeability and ameliorate neurological deficits and cognitive dysfunction in a mouse model of traumatic brain injury (TBI). Mechanistically, TGM2 likely modulates the IL‐17 signaling pathway to regulate MMP9 expression, thereby affecting BBB permeability.
Jieru Yang, Lihan Zhang, Xiancheng Qiu, Jiyang Wang, Ruicheng Yan, Jiasen Ye, Jianhua Peng, Yong Jiang   +7 more
wiley   +1 more source

Extensive Cerebral White Matter Involvement and Migrainous Headache in a Patient With Aquaporin-4-Positive NMOSD Mimicking CADASIL. [PDF]

Dement Neurocogn Disord
Lee S, Oh SI.
europepmc   +1 more source

A Review of Vagus Nerve Stimulation for Disease: Comprehensive Theory and Evidence for Mechanisms of Action

Comprehensive Physiology, Volume 16, Issue 2, April 2026.
Vagus nerve stimulation (VNS) effects span central and peripheral organ systems through diverse mechanistic pathways. This comprehensive review provides a unified synthesis of these mechanisms across neurological, cardiovascular, immunological, metabolic, and gastrointestinal domains, filling a critical gap and serving as a foundational resource for ...
Yifeng Bu, Alex Liang, Benjamin U. Hoffman, Dawn M. Schiehser, Oliver Case, Alan Simmons, Ruth Klaming, Andres Gottfried‐Blackmore, Ravinder K. Mittal, Christopher Puleo, Hubert Lim, Imanuel Lerman   +11 more
wiley   +1 more source