Results 51 to 60 of about 54,125 (306)

3D Printing Strategies for Bioengineering Human Cornea

Advanced Healthcare Materials, EarlyView.
This review highlights recent progress in 3D bioprinting strategies for engineering human corneas. Key aspects include the replication of corneal transparency, curvature, and biomechanical properties, alongside innovations in recent advancements in 3D printing methods, which benefit in overcoming current challenges.
Yunong Yuan, Khoon S. Lim, Gerard Sutton, Gordon G. Wallace, Jingjing You   +4 more
wiley   +1 more source

Levels of asymmetric dimethylarginine in plasma and aqueous humor: a key risk factor for the severity of fibrovascular proliferation in proliferative diabetic retinopathy

Frontiers in Endocrinology
IntroductionProliferative diabetic retinopathy (PDR) is a common diabetes complication, significantly impacting vision and quality of life. Previous studies have suggested a potential link between arginine pathway metabolites and diabetic retinopathy (DR)
Xinyang Guo, Wei Jin, Yiqiao Xing
doaj   +1 more source

Growth Hormone‐Loaded 3D Printed Silk Fibroin‐Cellulose Dressings for Ischemic Wounds

Advanced Healthcare Materials, EarlyView.
3D‐printed wound dressings combining carboxymethyl cellulose, silk fibroin, and growth hormone accelerate healing in diabetic ulcers. These bioactive, customizable dressings enhance angiogenesis, cellular proliferation, and immune modulation. Proteomic analysis reveals activation of regenerative pathways and reduced fibrosis, highlighting their ...
Maria Pita‐Vilar, Diego Caicedo‐Valdés, Susana B. Bravo, Isabel Rodriguez‐Moldes, Salvador D. Aznar‐Cervantes, Angel Concheiro, Carmen Alvarez‐Lorenzo, Luis Diaz‐Gomez   +7 more
wiley   +1 more source

Aqueous humor adipokine profile of primary open angle glaucoma patients and cataract patients with or without metabolic disorders [PDF]

International Journal of Ophthalmology
AIM: To investigate the role of adipokines in primary open angle glaucoma (POAG) by comparing the levels of these molecules in the aqueous humor among POAG patients and cataract patients with or without metabolic disorders.
Zi-Yao Xia, Ke Xu, Wei-Jia Zhang, De-Fu Wu, Zhe Pan, Hao-Cheng Xian, Xue-Min Li, Huai-Zhou Wang, Chun Zhang   +8 more
doaj   +1 more source

Alterations of aqueous humor Aβ levels in Aβ-infused and transgenic mouse models of Alzheimer disease.

PLoS ONE, 2020
Alzheimer's disease (AD) is an ageing-related neurodegenerative disease characterized and diagnosed by deposition of insoluble amyloid-β (Aβ) plaques in the brain.
Da Eun Kwak, Taeho Ko, Han Seok Koh, Yong Woo Ji, Jisu Shin, Kyeonghwan Kim, Hye Yun Kim, Hyung-Keun Lee, YoungSoo Kim   +8 more
doaj   +1 more source

Advances in Bioprinting to Model Immune‐Mediated Skin Diseases

Advanced Healthcare Materials, EarlyView.
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández, Marica Markovic, Julia Fernández‐Pérez, Georg Stary, Aleksandr Ovsianikov   +4 more
wiley   +1 more source

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

In vitro and in vivo datasets of topically applied ketorolac tromethamine in aqueous humor using Raman spectroscopy

Data in Brief, 2019
This article includes datasets acquired by Raman spectroscopy from in vivo and in vitro ocular samples collected from the dataset from Bertens and Zhang et al., “Confocal Raman spectroscopy: Evaluation of a non-invasive technique for the detection of ...
Shuo Zhang, Christian J.F. Bertens, Roel J. Erckens, Frank J.H.M. van den Biggelaar, Tos T.J.M. Berendschot, Carroll A.B. Webers, Rudy M.M.A. Nuijts, Marlies Gijs   +7 more
doaj   +1 more source

Quantification of intraocular interferon-gamma and IgG in cataract and diabetes [PDF]

, 2000
We applied the machine learning procedure to the analysis of serum and aqueous humor albumin, IgG and interferon-gamma patterns. The data were analyzed with respect to the cataract, type of diabetes, retinopathy and blood-aqueous humor barrier damage ...
Biserka Pokrić, Gordana Pavan, Josip Pavan, Milica Trbojević-Čepe, Nikola Štambuk, Paško Konjevoda   +5 more
core   +1 more source

Subconjunctival delivery of p75NTR antagonists reduces the inflammatory, vascular, and neurodegenerative pathologies of diabetic retinopathy [PDF]

, 2017
The p75NTR is a novel therapeutic target validated in a streptozotocin mouse model of diabetic retinopathy. Intravitreal (IVT) injection of small molecule p75NTR antagonist THX-B was therapeutic and resolved the inflammatory, vascular, and ...
Barcelona, Pablo Federico, Galan, Alba, Jian, Yifan, Nedev, Hinyu, Saragovi, H. Uri, Sarunic, Marinko V.   +5 more
core   +1 more source