Results 61 to 70 of about 54,125 (306)

Subicular Astrocytes Govern Seizure‐Impaired Fear Memory

open access: yesAdvanced Science, EarlyView.
Astrocytes in dorsal subiculum act as a critical modulator of seizure‐associated cognitive dysfunction, operating through a Ca2+‐dependent adenosine‐linked astrocyte‐neuron signaling pathway that disrupts neuronal circuit homeostasis. This research highlights the potential of astrocyte‐targeted interventions as a therapeutic strategy, moving beyond the
Yuying Shao   +15 more
wiley   +1 more source

Wild Rabbit Exposure to Leishmania infantum, Toxoplasma gondii, Anaplasma phagocytophilum and Babesia caballi Evidenced by Serum and Aqueous Humor Antibody Detection

open access: yesMicroorganisms, 2021
Wild rabbits (Oryctolagus cuniculus) can be important sentinel species for the presence of zoonotic pathogens. Therefore, we collected blood samples from wild rabbits harvested by hunters during the hunting season 2019–2020 on the island of Lemnos, to ...
Labrini V. Athanasiou   +5 more
doaj   +1 more source

Cryocautery and Aqueous Humor Dynamics [PDF]

open access: yes, 1966
A method of cyclocryocautery, using the Kelman Cryostylet, is described. On rabbit eyes this brings about a statistically significant lowering of intraocular pressure and reduction of aqueous flow over an observation period of three months.
Wiesinger, Herbert
core   +1 more source

Intraluminal Deposits Found in Glaucoma Tube Shunts Via Anterior Segment Ocular Coherence Tomography [PDF]

open access: yes, 2018
PURPOSE: To describe and characterize a novel observation of intraluminal deposits of glaucoma tube shunts (TS) using spectral domain (SD) ocular coherence topography (OCT).
Alvarado, Jorge A.   +2 more
core   +1 more source

Bioinspired Tissue Transparency: Achieving Sclera‐to‐Cornea Transplantation

open access: yesAdvanced Science, EarlyView.
A bioinspired decellularization‐compression‐locking tactic (DCLT) is developed to transform human sclerae into transparent corneal substitutes. These clear, robust, and pro‐regenerative substitutes are capable of repairing complex corneal injuries, including chemical burns, keratoconus, and penetrating wounds, demonstrating their clinical potential to ...
Xiuli Sun   +8 more
wiley   +1 more source

Tissue Distribution of trans-Resveratrol and Its Metabolites after Oral Administration in Human Eyes

open access: yesJournal of Ophthalmology, 2017
Purpose. This study was performed to measure the concentration of trans-resveratrol and its three metabolites in human eyes. Methods. The patients who underwent pars plana vitrectomy for rhegmatogenous retinal detachment were included.
Shuaishuai Wang   +7 more
doaj   +1 more source

Soft‐Drug‐Inspired MnSTF Nano‐Adjuvant for Safe and Synergistic cGAS–STING Activation in Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study introduces MnSTF, a soft‐drug‐inspired nanoadjuvant that overcomes the systemic toxicity of STING agonists. Through Mn2+ coordination with an ENPP1 inhibitor, it enables safe cGAS‐STING activation, remodels the tumor immune microenvironment, and synergizes with radiotherapy or vaccines to elicit robust antitumor immunity.
Guangfei Sun   +8 more
wiley   +1 more source

Fluorophotometric measurements of aqueous-humor flow in Filipino eyes

open access: yesPhilippine Journal of Ophthalmology, 2007
Objective: This study determined the rate of aqueous-humor flow in Filipino eyes. Methods: Patients were recruited from the outpatient eye clinic of the Philippine General Hospital.
George Emmanuel S.J. Comia, MD   +2 more
doaj  

Differences between Aqueous Humor and Serum Concentrations of BDNF and PPARG Genetic Variants in Glaucoma Patients

open access: yesActa Clinica Croatica
Brain-derived neurotrophic factor (BDNF) is essential for neuronal development, differentiation and survival, and aberrant BDNF expression in retina is associated with glaucoma.
Tena Križ   +6 more
doaj   +1 more source

The prognosis of trabeculectomy in primary angle- closure glaucoma patients [PDF]

open access: yesInternational Journal of Ophthalmology, 2019
AIM: To evaluate whether the level of thrombospondin-1 (TSP-1) in aqueous humor can predict the prognosis of trabeculectomy in patients with primary angle-closure glaucoma (PACG).
Jun-Dong Zhu   +3 more
doaj   +1 more source

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