Results 61 to 70 of about 10,938 (174)

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

Arabinogalactan proteins

Frontiers in Plant Science, 2014
Arabinogalactan proteins (AGPs) are a highly diverse class of cell surface proteoglycans that are commonly found in most plant species. AGPs play important roles in many cellular processes during plant development, such as reproduction, cell proliferation, pattern formation and growth, and in plant-microbe interaction.
Knoch, Eva, Dilokpimol, Adiphol, Geshi, Naomi   +2 more
openaire   +1 more source

Structural and thermodynamic analyses of a novel β‐1,2‐glucan binding mode in the ABC transporter solute‐binding protein Chy400_4166 from Chloroflexus aurantiacus

The FEBS Journal, EarlyView.
Cyclic β‐1,2‐glucan (CβG)‐associated solute‐binding protein of type I ABC transporter was originally identified in Chloroflexus aurantiacus, a phototrophic bacterium. Crystal structures in complex with CβGs revealed unique binding modes that are fundamentally distinct from that of the short β‐1,2‐glucooligosaccharides‐binding protein.
Kazuya Kato, Tatsuya Kaneko, Rintaro Hirayama, Nobukiyo Tanaka, Hiroyuki Nakai, Hidetaka Torigoe, Masahiro Nakajima   +6 more
wiley   +1 more source

Metabolomic Analysis Reveals Structural Diversity of Pectic Polysaccharides From Prunus persica (L.) Batsch and Their Relationship With Purees Characteristics

Plant Biotechnology Journal, EarlyView.
ABSTRACT To clarify how pectin heterogeneity relates to puree quality, this study investigated associations among pectin fractions, metabolite profiles, and physicochemical properties of peach purees from 20 cultivars with distinct viscosity, turbidity, and colour.
Meng Liu, Xuan Liu, Shaojie Fu, Qianhui Yang, Christophe Blecker, Jinfeng Bi   +5 more
wiley   +1 more source

Arabinogalactan proteins

Current Opinion in Plant Biology
Arabinogalactan proteins (AGPs) are highly glycosylated cell wall proteins essential for plant growth and reproduction. AGPs are extensively decorated with arabinogalactan polysaccharides, composed primarily of arabinose and galactose, along with minor sugars such as glucuronic acid, fucose, and rhamnose.
Silva, Jessy, Moreira, Diana, Ferreira, Maria João, Pereira, Ana Marta, Pereira, Luís Gustavo, Coimbra, Sílvia   +5 more
openaire   +1 more source

Isolation and Characterization of Pectic Polysaccharide Fraction from In Vitro Suspension Culture of Fumaria officinalis L.

International Journal of Polymer Science, 2018
In the current study, an acidic polysaccharide from the in vitro suspension culture of Fumaria officinalis L. was obtained by extraction with 0.8% (w/v) aqueous ammonium oxalate.
Manol Ognyanov, Yordan Georgiev, Nadezhda Petkova, Ivan Ivanov, Ivelina Vasileva, Maria Kratchanova   +5 more
doaj   +1 more source

Unexpected Suppression of Tomato Fruit Cuticle Formation by Overexpression of a Key Cutin Biosynthetic Enzyme

Plant Biotechnology Journal, EarlyView.
ABSTRACT Fruit cuticles regulate the diffusion of water, gases and solutes, functioning as essential protective interfaces against environmental and biotic stresses. Engineering cuticle structure and mechanics therefore represents a promising strategy for improving fruit quality and resilience.
Gulab Chand Arya, Ekram Wassel, Vibha Mishra, Ekaterina Manasherova, Ruth E. Stark, Hagai Cohen   +5 more
wiley   +1 more source

Therapeutic effect of NEO400, perillyl alcohol conjugated to linoleic acid, in a mouse model of UV‐induced skin damage

Photochemistry and Photobiology, Volume 101, Issue 2, Page 338-349, March/April 2025.
In the present work with mouse models, we demonstrate that a novel compound, NEO400, is able to profoundly protect skin against damage caused by UV radiation (UVR) when it is applied to skin post‐UVR exposure. In comparison, Aloe vera or linoleic acid are unable to achieve a similar level of protection.
Stephen Swenson, Catalina Silva‐Hirschberg, Liliana Freeland, Kristen L. Chen, Nagore I. Marín‐Ramos, Axel H. Schönthal, Thomas C. Chen   +6 more
wiley   +1 more source

The evolutionary origins of streptophyte multicellularity

New Phytologist, Volume 251, Issue 5, Page 2365-2383, September 2026.
The phylogeny of streptophytes and the deep origin of branching filamentous growth. Summary Over their more than 1 billion years of evolutionary history, streptophytes have repeatedly transitioned between unicellular, simple multicellular and complex multicellular forms.
Tatyana Darienko, Cäcilia F. Kunz, Elisa S. Goldbecker, Erika Endriulaitytė, Maaike J. Bierenbroodspot, Maike Lorenz, Iker Irisarri, Thomas Pröschold, Katharina Bürstenbinder, Henrik Buschmann, Jan de Vries   +10 more
wiley   +1 more source

Development and Functional Evaluation of a Pharmabiotic Food Supplement Containing Microencapsulated Lactiplantibacillus pentosus for Oral Microbiome Health

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Development of a multifunctional pharmabiotic oral spray containing microencapsulated Lactiplantibacillus pentosus, hyaluronic acid, and Glycyrrhiza glabra extract. The formulation synergistically suppresses oral biofilms while exhibiting antimicrobial and antioxidant activities, supporting oral microbiome homeostasis.
Pervin Soyer, A. Alper Öztürk
wiley   +1 more source