Results 101 to 110 of about 17,329 (193)

Differential regulation of 5-lipoxygenase and leukotriene-C4-synthase expression by IFNγ, IL-4 and IL-13 in human monocytes and macrophages from patients with atopic dermatitis. [PDF]

Inflamm Res
Lietzau S, Traidl S, Riesselmann C, Werfel T, Mommert S.   +4 more
europepmc   +1 more source

Positive effects of bile acids alleviating heat stress in laying hens by enhancing immunity via metabolome and transcriptome integration. [PDF]

Poult Sci
Geng X, Wang S, Tian Y, Chen X, Wang X, Yao S, Chen H, Hao E, Shi L, Wang D, Chen Y.   +10 more
europepmc   +1 more source

12/15-lipoxygenase mediates disturbed flow-induced endothelial dysfunction and atherosclerosis. [PDF]

Mol Med
Chen JW, Chen SL, Wu XR, Shu XY, Tang SY, Yuan H, Li YR, Quan JW, Feng S, Zhang RY, Yang CD, Lu L, Wang XQ.   +12 more
europepmc   +1 more source

Recent Advances in Dual COX/LOX Inhibitor Design (2020-2024): Establishing "The Rule of Four for Inflammation". [PDF]

Life (Basel)
Chatzipieris FP, Petsas E, Lambrinidis G, Vassiliou S, Chasapis CT.   +4 more
europepmc   +1 more source

Inhibition of 12/15-LOX hyperactivation mitigates cognitive decline in a chronic cerebral hypoperfusion mouse model and in H₂O₂-induced HT22 cells: therapeutic effects of brozopine. [PDF]

J Enzyme Inhib Med Chem
Wang X, Lu Z, Shao Q, Wang Y, Zhang Z, Wang Z, Jia Q, Zhu J, Song Y, Yuan L, Wang Y, Xu S, He L, Chang J, Gao Y.   +14 more
europepmc   +1 more source

Eosinophils and pleural macrophages counter regulate IL-33-elicited airway inflammation via the 12/15-lipoxygenase pathway. [PDF]

Front Immunol
Ito E, Hayashizaki R, Hosaka T, Yamane T, Miyata J, Isobe Y, Arita M.   +6 more
europepmc   +1 more source

Computational prediction of the pathogenic variants of arachidonate 5-lipoxygenase activating protein using Molecular Dynamics simulation. [PDF]

PLoS One
Elnageeb ME, Elfaki I, Modawe GA, Elfaki AO, Alzahrani OR, Abuagla HA, Alwabsi HA, I Alalawy A, Ajmal MR, Mohamed EI, Eledum H, Mustafa SK, Alhathli EM.   +12 more
europepmc   +1 more source

Design, synthesis, characterization, biological investigation and docking studies of newly synthesized sulphonyl hydrazide and their derivatives. [PDF]

Sci Rep
Rahman M, Zafar R, Jan MS, Darwish HW, Khattak H, Aschner M, Daglia M, Khan H.   +7 more
europepmc   +1 more source

INHIBITING ALOX15 PREVENTS MYOCARDIAL INJURY INDUCED BY EXERTIONAL HEAT STROKE. [PDF]

Shock
Zhao Y, Tuo W, Wu X, Gou R, Hou L, Liu J, Li G.   +6 more
europepmc   +1 more source

Celastrol suppresses bone destruction in rheumatoid arthritis by inhibiting ALOX5 expression in macrophages via the NF-κB pathway. [PDF]

Sci Rep
Chen Y, Wang Z, Chen Y, Liu X, Liu L, Tu Z, Tao Q, Xu Y.   +7 more
europepmc   +1 more source