Results 181 to 190 of about 15,557 (213)
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Synthesis of two analogues of arachidonic acid and their reactions with 12-Lipoxygenase
Tetrahedron, 1990Abstract Two analogues of arachidonic acid (AA) were synthesized and their reaction with purified porcine 12-lipoxygenase was investigated. The analogue (Z,Z,Z,E)-5,8,11,13 eicosatetraienoic acid 1 was found to be a substrate for the enzyme, being oxidized at one third the rate of AA.
Marc Labelle +3 more
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Tissue Distribution and Subcellular Localization of Platelet-Type Arachidonate 12-Lipoxygenase
1997Arachidonate 12-lipoxygenase introduces one oxygen molecule regiospecifically and stereoselectively into the carbon 12 of arachidonic acid. Our group has demonstrated the occurrence of two isoforms of 12-lipoxygenase (platelet-type and leukocyte-type) which were distinguished in terms of substrate specificity, the cross-reactivity of their antibodies ...
M, Nakamura +5 more
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Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1993
On the basis of the previous work by Okuma and Uchino [Blood 54, 1258-1271, 1979], three patients with myeloproliferative disorders were investigated with a special reference to arachidonate 12-lipoxygenase in their platelets. The cytosol of the patients' platelets showed a markedly reduced activity of arachidonic acid oxygenation to 12-hydroperoxy ...
S, Matsuda +8 more
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On the basis of the previous work by Okuma and Uchino [Blood 54, 1258-1271, 1979], three patients with myeloproliferative disorders were investigated with a special reference to arachidonate 12-lipoxygenase in their platelets. The cytosol of the patients' platelets showed a markedly reduced activity of arachidonic acid oxygenation to 12-hydroperoxy ...
S, Matsuda +8 more
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Archives of Biochemistry and Biophysics, 1988
12-Lipoxygenases were found in the cytosol fraction of bovine leukocytes and platelets. The bovine leukocyte enzyme was immunoprecipitable by a monoclonal antibody directed to 12-lipoxygenase of porcine leukocytes, but not by a monoclonal antibody against the human platelet enzyme.
Y, Takahashi, N, Ueda, S, Yamamoto
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12-Lipoxygenases were found in the cytosol fraction of bovine leukocytes and platelets. The bovine leukocyte enzyme was immunoprecipitable by a monoclonal antibody directed to 12-lipoxygenase of porcine leukocytes, but not by a monoclonal antibody against the human platelet enzyme.
Y, Takahashi, N, Ueda, S, Yamamoto
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BglII RFLP at the porcine arachidonate 12‐lipoxygenase (LOG12) locus
Animal Genetics, 1994M B, Coscelli +3 more
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