Results 131 to 140 of about 3,155 (186)

Beyond oxidative stress: Ferroptosis as a novel orchestrator in neurodegenerative disorders. [PDF]

Front Immunol
Yi Y, Jia P, Xie P, Peng X, Zhu X, Yin S, Luo Y, Deng Y, Wan L.   +8 more
europepmc   +1 more source

Targeting cell death pathways in acute myeloid leukemia: Molecular mechanisms and clinical implications (Review). [PDF]

Oncol Rep
Jianati R, Chen H, Yang X, Yan L, Guo Y, Fan C, Hao X, Zhu G, Shi Z.   +8 more
europepmc   +1 more source

Characterization of Differential GPX4 Essentiality Between Intrahepatic and Extrahepatic Cholangiocarcinoma via Leveraging of a Large-Scale Functional Genomic Screen. [PDF]

Int J Mol Sci
Lee YR, Seo C, Abdullah M, Baek SH, Lee SJ.   +4 more
europepmc   +1 more source

Exercise Improves Sarcopenic Obesity Through Inhibition of Ferroptosis and Activation of the AMPK/ACC Pathway. [PDF]

Int J Mol Sci
Ru Q, Xu C, Wan C, Cheng B, Xiang X, Fang L, Ren J, Chen L, Wu Y.   +8 more
europepmc   +1 more source

Ferroptosis in cancer: metabolism, mechanisms and therapeutic prospects. [PDF]

Mol Cancer
Wu Y, Li H, Yue K, Jing C, Duan Y.
europepmc   +1 more source

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Arachidonate 12-lipoxygenases

Prostaglandins & Other Lipid Mediators, 2002
Arachidonate 12-lipoxygenase introduces a molecular oxygen at carbon 12 of arachidonic acid to generate a 12-hydroperoxy derivative. The enzymes generate 12-hydroperoxy derivatives with either S- or R-configurations. There are three isoforms of 12S-lipoxygenases named after the cells where they were first identified; platelet, leukocyte and epidermis ...
Tanihiro, Yoshimoto, Yoshitaka, Takahashi   +1 more
openaire   +2 more sources

Mammalian arachidonate 15-lipoxygenases

Prostaglandins & Other Lipid Mediators, 2002
Hartmut Kuhn, Matthias Walther, Ralf Jürgen Kuban   +2 more
openaire   +3 more sources

Epidermal arachidonate lipoxygenase

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1983
Guinea pig skin was found to display a high lipoxygenase activity, evidenced by the formation of a hydroxyeicosatetraenoic acid (HETE) from exogenous [14C]arachidonic acid. The lipoxygenase activity was localized to the epidermal layer of the skin, was completely inhibited by eicosatetraynoic acid (ETYA) and slightly enhanced by indomethacin ...
T, Ruzicka, A, Vitto, M P, Printz
openaire   +2 more sources

Arachidonate 8(S)-lipoxygenase

Prostaglandins & Other Lipid Mediators, 2002
The recently identified mouse 8(S)-lipoxygenase almost exclusively directs oxygen insertion into the 8(S) position of arachidonic acid and, with lower efficiency, into the 9(S) position of linoleic acid. The protein of 677 amino acids displays 78% sequence identity to human 15(S)-lipoxygenase-2 which is considered to be its human orthologue.
Gerhard, Fürstenberger, Friedrich, Marks, Peter, Krieg   +2 more
openaire   +2 more sources