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Causality of genetically determined blood metabolites on inflammatory bowel disease: a two-sample Mendelian randomization study. [PDF]
Sci RepLong X +6 more
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Structural and Functional Characterization of Lipoxygenases from Diatoms by Bioinformatics and Modelling Studies. [PDF]
BiomoleculesGiordano D +4 more
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Ferroptosis in cancer toward molecular insights and clinical translation in pancreatic cancer. [PDF]
Mol CancerChen Q +8 more
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Recent Advances in Dual COX/LOX Inhibitor Design (2020-2024): Establishing "The Rule of Four for Inflammation". [PDF]
Life (Basel)Chatzipieris FP +4 more
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Prostaglandins and Other Lipid Mediators, 2002
Arachidonate 12-lipoxygenase introduces a molecular oxygen at carbon 12 of arachidonic acid to generate a 12-hydroperoxy derivative. The enzymes generate 12-hydroperoxy derivatives with either S- or R-configurations. There are three isoforms of 12S-lipoxygenases named after the cells where they were first identified; platelet, leukocyte and epidermis ...
Tanihiro Yoshimoto +1 more
exaly +3 more sources
Arachidonate 12-lipoxygenase introduces a molecular oxygen at carbon 12 of arachidonic acid to generate a 12-hydroperoxy derivative. The enzymes generate 12-hydroperoxy derivatives with either S- or R-configurations. There are three isoforms of 12S-lipoxygenases named after the cells where they were first identified; platelet, leukocyte and epidermis ...
Tanihiro Yoshimoto +1 more
exaly +3 more sources
Mammalian Arachidonate 12-Lipoxygenases
Advances in Experimental Medicine and Biology, 1997Since arachidonate 12-lipoxygenase was earlier found in platelets as the first mammalian lipoxygenase, the enzyme has been found in a variety of tissues of a number of animal species. On the basis of our studies in the last decade, we have demonstrated that there are two isoforms of 12-lipoxygenase (1).
G R Reddy +2 more
exaly +3 more sources
Critical Role of Arachidonate Lipoxygenases in Regulating Apoptosis
Advances in Experimental Medicine and Biology, 1997Aoptosis, or programmed cell death, is a genetically encoded cell suicide program defined by characteristic morphologic, biochemical, and molecular changes resulting in nonpathologic cell loss. A large number of distinct cellular phenotypes set apoptosis apart from another cell death process, i.
Dean G Tang +2 more
exaly +3 more sources