Results 1 to 10 of about 5,983,147 (303)

Increasing dietary linoleic acid does not increase tissue arachidonic acid content in adults consuming Western-type diets: a systematic review

open access: yesNutrition & Metabolism, 2011
Background Linoleic acid, with a DRI of 12-17 g/d, is the most highly consumed polyunsaturated fatty acid in the Western diet and is found in virtually all commonly consumed foods.
Whelan Jay, Rett Brian S
doaj   +2 more sources

Arachidonic Acid Measurement [PDF]

open access: yesDefinitions, 2020
The of the amount of arachidonic acid present in a sample.
openaire   +2 more sources

The discovery and early structural studies of arachidonic acid

open access: yesJournal of Lipid Research, 2016
Arachidonic acid and esterified arachidonate are ubiquitous components of every mammalian cell. This polyunsaturated fatty acid serves very important biochemical roles, including being the direct precursor of bioactive lipid mediators such as ...
Sarah A. Martin   +2 more
doaj   +2 more sources

Arachidonic acid metabolism in health and disease

open access: yesMedComm, 2023
Arachidonic acid (AA), an n‐6 essential fatty acid, is a major component of mammalian cells and can be released by phospholipase A2. Accumulating evidence indicates that AA plays essential biochemical roles, as it is the direct precursor of bioactive ...
Yiran Zhang   +5 more
semanticscholar   +1 more source

Effects of Arachidonic Acid Metabolites on Cardiovascular Health and Disease

open access: yesInternational Journal of Molecular Sciences, 2021
Arachidonic acid (AA) is an essential fatty acid that is released by phospholipids in cell membranes and metabolized by cyclooxygenase (COX), cytochrome P450 (CYP) enzymes, and lipid oxygenase (LOX) pathways to regulate complex cardiovascular function ...
Yan Zhou   +3 more
semanticscholar   +1 more source

Molecular mechanisms underlying the actions of arachidonic acid-derived prostaglandins on peripheral nociception

open access: yesJournal of Neuroinflammation, 2020
Arachidonic acid-derived prostaglandins not only contribute to the development of inflammation as intercellular pro-inflammatory mediators, but also promote the excitability of the peripheral somatosensory system, contributing to pain exacerbation ...
Yongwoo Jang, Minseok Kim, S. Hwang
semanticscholar   +1 more source

Metabolism pathways of arachidonic acids: mechanisms and potential therapeutic targets

open access: yesSignal Transduction and Targeted Therapy, 2021
The arachidonic acid (AA) pathway plays a key role in cardiovascular biology, carcinogenesis, and many inflammatory diseases, such as asthma, arthritis, etc.
Bei Wang   +8 more
semanticscholar   +1 more source

Arachidonic acid depletion extends survival of cold-stored platelets by interfering with the [glycoprotein Ibα – 14-3-3ζ] association

open access: yesHaematologica, 2012
Background Cold storage of platelets reduces bacterial growth and preserves their hemostatic properties better than current procedures do. However, storage at 0°C induces [14-3-3ζ-glycoprotein Ibα] association, 14-3-3ζ release from phospho-Bad, Bad ...
Dianne E. van der Wal   +6 more
doaj   +1 more source

The Contribution of Cytosolic Group IVA and Calcium-Independent Group VIA Phospholipase A2s to Adrenic Acid Mobilization in Murine Macrophages

open access: yesBiomolecules, 2020
Adrenic acid (AA), the 2-carbon elongation product of arachidonic acid, is present at significant levels in membrane phospholipids of mouse peritoneal macrophages.
Patricia Monge   +6 more
doaj   +1 more source

Chronic N-methyl-d-aspartate administration increases the turnover of arachidonic acid within brain phospholipids of the unanesthetized rat

open access: yesJournal of Lipid Research, 2008
Whereas antibipolar drug administration to rats reduces brain arachidonic acid turnover, excessive N-methyl-d-aspartate (NMDA) signaling is thought to contribute to bipolar disorder symptoms and may increase arachidonic acid turnover in rat brain ...
Ho-Joo Lee   +4 more
doaj   +1 more source

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