Results 121 to 130 of about 189,223 (341)
The ethanolamine-containing glycerophospholipids, choline-containing glycerophospholipids, and phosphatidylinositol fractions are major sources of arachidonic acid in murine mastocytoma P-815 cloned cells.
S Yoshioka+3 more
doaj
NSAIDS AS MODULATORS OF CATION CHANNELS: FENAMATES REPURPOSING IN CHANNELOPATHIES
Cationic ion channels are transmembrane proteins that regulate the flux of cations (potassium, sodium, and calcium) across cell membrane, playing a pivotal role in many cellular functions. Disruptions of their activity can lead to the so‐called genetic or acquired channelopathies, a heterogeneous group of diseases that affect multiple human systems ...
Paola Laghetti+4 more
wiley +1 more source
Arachidonic acid metabolism in polymorphonuclear leukocytes: unstable intermediate in formation of dihydroxy acids. [PDF]
P Borgeat, Bengt Samuelsson
openalex +1 more source
An experimental and computational investigation on the regio‐ and enantioselective hydroxylation of arachidonic acid by several unspecific peroxygenases (UPOs) revealed rAaeUPO A77L variant as the most attractive candidate for the selective production of valuable hydroxy‐fatty acids because of its enhanced regio and enantioselectivity and reduced ...
Alejandro González‐Benjumea+7 more
wiley +1 more source
Diversity of Antibacterial Compounds From Eucheuma Serra, Halimeda Opuntia, and Hydroclathrus Clathratus [PDF]
Fourteen compounds were isolated from acetone extracts of three species of seaweeds (Eucheuma serra, a red seaweed, Halimeda opuntia, a green seaweed, and Hydroclathrus clathratus, a brown seaweed) using bioautographic TLC methods and identified using GC-
Anggadiredja, J. T. (Jana)
core
Effects of Arachidonic Acid and Its Metabolites on Antigen-Induced Histamine Release from Human Basophils in Vitro [PDF]
Gianni Marone+2 more
openalex +1 more source
ABSTRACT Pharmacokinetics is the study of the movement of drug in the body and includes the processes of absorption, distribution, metabolism, and excretion. Pharmacodynamics is the pharmacologic effect of the drug on the body. The pharmacokinetics of a drug determines its pharmacologic effect. Pharmacokinetic studies describe drug concentrations while
Heather K. Knych
wiley +1 more source
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia+2 more
wiley +1 more source
Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis
Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen+7 more
wiley +1 more source
SELECTIVE INHIBITORY ACTIONS OF SODIUM‐p‐BENZYL‐4‐[1‐OXO‐2‐(4‐CHLOROBENZYL)‐3‐PHENYL PROPYL] PHENYL PHOSPHONATE (N‐O164) AND INDOMETHACIN ON THE BIOSYNTHESIS OF PROSTAGLANDINS AND THROMBOXANES FROM ARACHIDONIC ACID [PDF]
K.E. Eakins, Prasad S. Kulkarni
openalex +1 more source