Results 101 to 110 of about 2,614,074 (305)

Process For Producing A Polyunsatured Fatty Acid Comprising Arachidonic Acid (Patent EP 2380984 B1) [PDF]

, 2017
The invention relates to nucleic acid derived from Perkinsus marinus which encodes a 9-elongase, a ”8-desaturase and a ”5-desaturase enzyme.
Sayanova, O. V., Napier, J. A., Venegas Caleron, M.   +2 more
core  

Arachidonic acid matters

, 2022
Arachidonic acid ...
GM Turchini (14160615), X Meng (9848132), H Xu (4701343), Q Ma (7767173), Y Wei (10361159), M Liang (7856657)   +5 more
core  

Gut Health in Ostriches (Struthio camelus): Insights Into Intestinal Structure, Functions, Microbiome, and Improvement Strategies

Animal Research and One Health, EarlyView.
Our paper systematically reviews the intestinal structure, function, and microbiota of ostriches, along with strategies for improving their gut health. We analyze how these factors collectively influence intestinal homeostasis and ostrich welfare, emphasizing probiotics as a promising intervention to enhance gut health, boost population well‐being, and
Zi‐Qun Zhang, Fang‐Fang Guo, Wen‐Juan Du, Meng Li, Aftab Shaukat, Zhu‐Qing Jia, Shu‐Cheng Huang   +6 more
wiley   +1 more source

The phosphoinositide 3-kinase-dependent activation of Btk is required for optimal eicosanoid production and generation of reactive oxygen species in antigen-stimulated mast cells

, 2008
Activated mast cells are a major source of the eicosanoids PGD(2) and leukotriene C(4) (LTC(4)), which contribute to allergic responses. These eicosanoids are produced following the ERK1/2-dependent activation of cytosolic phospholipase A(2), thus ...
Hye Sun Kuehn, Gilfillan, Alasdair M., Michael A. Beaven, Alasdair M. Gilfillan, Kuehn, Hye Sun, Dean D. Metcalfe, Beaven, Michael A., Emily J. Swindle, Swindle, Emily J., Mi-Sun Kim, Kim, Mi-Sun, Metcalfe, Dean D.   +11 more
core   +2 more sources

Polymorphisms in the genes involved in the arachidonic acid-pathway, fish consumption and the risk of colorectal cancer. [PDF]

, 2006
The objective of this study on colorectal cancer was to investigate the associations between SNPs in the genes involved in the arachidonic acid (AA)-pathway, their haplotypes and colorectal cancer. Moreover, interactions between SNPs and fish consumption
Siezen, Christine L E, Siezen, C.L., Kranen, Henk J van, Marina van Doeselaar, Petra H.M. Peeters, Nicolien R. Kram, Bueno de Mesquita, H.B., Peeters, P.H.M., Kram, N.R., van Doeselaar, M., van Kranen, H.J., Doeselaar, Marina van, H. Bas Bueno‐de‐Mesquita, Kram, Nicolien R, Christine L.E. Siezen, Henk J. van Kranen, Bueno-de-Mesquita, H Bas, Peeters, Petra H M   +17 more
core   +1 more source

Evaluation of a pantoprazole and 4‐desmethylpantoprazole‐sulfate metabolic ratio as a novel CYP2C19 phenotyping method

British Journal of Clinical Pharmacology, EarlyView.
Aims CYP2C19 is one of the most important pharmacogenes, and its activity is highly variable due to factors such as genetics or drug–drug interactions. Due to the lack of an appropriate endogenous CYP2C19 biomarker, surrogate methods to assess its activity are warranted.
Julian Peter Müller, Vladimir N. Belov, Sabrina Yamoune, Bob Miller, Mohammed Hasoumi, Jolanta Tupiec, Thea Laurentius, L. Cornelius Bollheimer, Julia C. Stingl, Katja S. Just   +9 more
wiley   +1 more source

Metabolomic analysis reveals the role of gut microbiota metabolic disorders in heart failure due to congenital heart disease

Scientific Reports
This study aimed to explore the effects of gut microbiota metabolic disorders caused by gut microbiota dysbiosis on heart failure due to congenital heart disease (CHD) through metabolomic analysis. Patients with congestive heart failure caused by left-to-
Qi-Liang Zhang, Qiong-Xia Ou, Yi Wang, Yi-Nan Liu, Ya-Ting Zeng, Qiang Chen, Zeng-Chun Wang   +6 more
doaj   +1 more source

Sonic Hedgehog Activates Phospholipase A2 to Enhance Smoothened Ciliary Translocation

Cell Reports, 2017
The G protein-coupled receptor Smoothened (Smo) is the signal transducer of the Sonic Hedgehog (Shh) pathway. Smo signals through G protein-dependent and -independent routes, with G protein-independent canonical signaling to Gli effectors requiring Smo ...
Angela M. Arensdorf, Miriam E. Dillard, Jacob M. Menke, Matthew W. Frank, Charles O. Rock, Stacey K. Ogden   +5 more
doaj   +1 more source

arachidonic acid metabolism-png

, 2014
unigenes mapped to arachidonic acid ...
Karen Fugate (480954)
core   +1 more source

Whole‐Cell Production of Resolvin E2 and 17R‐Resolvin D5 by a Double‐Oxygenating 15S‐Lipoxygenase With 5S‐Lipoxygenase Activity From Pseudobdellovibrionaceae bacterium

Biotechnology and Bioengineering, EarlyView.
A recombinant whole‐cell platform expressing a bacterial 15S‐LOX exhibiting 5S‐LOX activity enabled the stereoselective production of RvE2 and 17R‐RvD5 from 18R‐HEPE and 17R‐HDHA, achieving final concentrations of 0.57 mM and 1.48 mM from 4.0 mM substrates, respectively, under optimized conditions.
Hee‐Gyeong Lee, Kyung‐Chul Shin, Deok‐Kun Oh   +2 more
wiley   +1 more source