Results 121 to 130 of about 2,614,074 (305)
A bioinspired catalytic nanoplatform for ferroptosis‐immunotherapy synergy in metastatic cancer
BMEMat, EarlyView.The bioinspired nanoplatform MnMSN@MnP‐PEG co‐delivers manganese peroxidase and manganese ions to synergistically induce immunogenic ferroptosis and activate the cGAS‐STING pathway, eliciting potent antitumor immunity against primary and metastatic tumors.
Panpan Xue +8 more
wiley +1 more source
The chemistry of arachidonic acid oxygenation by prostaglandin endoperoxide synthase
Redox Biochemistry and ChemistryProstaglandins are an important class of bioactive lipids derived from arachidonic acid. The different classes of prostaglandins are produced from a common intermediate, called prostaglandin H2.
Lawrence J. Marnett
doaj +1 more source
, 2014 Extracellular milieu; metabolite levels in μM; IR vs. IS; n = 10; (A) 15S-HETE: 15-hydroxy-eicosatetraenoic acid, median test; (B) AA: arachidonic acid, Wilcoxon; (C) DHA: docosahexaenoic acid (Wilcoxon). Horizontal line means grand mean.
Tobias Meile (545989) +12 more
core +1 more source
Lipid droplet profiling during neutrophil differentiation by stimulated Raman scattering microscopy
Biotechnology Progress, EarlyView.Abstract Lipid droplets (LDs) are dynamic organelles that serve as metabolic hubs and emerging regulators of immune cell fate. Although LDs have been implicated in immune regulation, how LD metabolism is remodeled during neutrophil differentiation and how stage‐specific LD dynamics shape mature neutrophil function remain poorly defined.
Ting‐Jung Sung +5 more
wiley +1 more source
METABOLISM OF ARACHIDONIC ACID IN PHOSPHOLIPID
The Keio Journal of Medicine, 1966 After albino rats were starved or fed with the fat and pyridoxine deficient diet, linoleic, linolenic and arachidonic acids and pyridoxine were administered. The amount of polyunsaturated fatty acids in phospholipid of the liver and muscle was then determined and the following results were obtained.1) Even if rats were fed on the fat deficient diet or ...
openaire +3 more sources
, 2018 Yazun Bashir Jarrar, Luay Al-Essa, Abdulhasib Kilani, Mariam Hasan, Walid Al-Qerem Department of Pharmacy, College of Pharmacy, Al-Zaytoonah University of Jordan, Airport street, Amman, Jordan Background: Diabetic patients have lower capacity to ...
Kilani A +4 more
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Arachidonic acid in Alzheimer's disease
, 2016 International audienceAlzheimer’s disease is a very complex disease in which neuroinflammation and synaptic dysfunctions play a critical role in association with the two well-known molecular agents of the disease, the Aβ1-42 peptide oligomers and the ...
Olivier, Jean-Luc +3 more
core +1 more source
Developmental Dynamics, EarlyView.Abstract Neural crest cells are multipotent, migratory stem‐like cells essential for vertebrate development that contribute broadly to many tissues including the craniofacial skeleton, peripheral nervous system, and pigment‐producing cells. Their development progresses through phases of induction, specification, delamination, migration, and ...
Allison E. Mancini +2 more
wiley +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia +2 more
wiley +1 more source
The target of arachidonic acid pathway is a new anticancer strategy for human prostate cancer
, 2008 Masahide Matsuyama, Rikio YoshimuraDepartment of Urology, Osaka City University Graduate School of Medicine, Osaka, JapanAbstract: Recent epidemiological studies and animal experiments have demonstrated that nonsteroidal anti-inflammatory drugs (NSAIDs ...
Rikio Yoshimura, Masahide Matsuyama
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