Results 111 to 120 of about 122,999 (308)

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia   +2 more
wiley   +1 more source

Effect of fatty acid saturation on NADPH-dependent lipid peroxidation in rat liver microsomes.

open access: yesJournal of Lipid Research, 1981
NADPH-dependent lipid peroxidation in liver microsomes, as measured by malondialdehyde formation, decreased by 90% when rats were fed a diet containing 16% coconut oil.
B R Lokesh, S N Mathur, A A Spector
doaj   +1 more source

arachidonic acid metabolism-html

open access: yes, 2014
unigenes mapped to arachidonic acid ...
Karen Fugate (480954)
core   +1 more source

Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1358-1373, April 2025.
Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen   +7 more
wiley   +1 more source

The chemistry of arachidonic acid oxygenation by prostaglandin endoperoxide synthase

open access: yesRedox Biochemistry and Chemistry
Prostaglandins are an important class of bioactive lipids derived from arachidonic acid. The different classes of prostaglandins are produced from a common intermediate, called prostaglandin H2.
Lawrence J. Marnett
doaj   +1 more source

Arachidonic acid cytochrome P450 epoxygenase pathway

open access: yesJournal of Lipid Research, 2009
Cytochrome P450 (CYP) epoxygenases convert arachidonic acid to four epoxyeicosatrienoic acid (EET) regioisomers, 5,6-, 8,9-, 11,12-, and 14,15-EET, that function as autacrine and paracrine mediators.
Arthur A. Spector
doaj   +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

open access: yesEpilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza   +4 more
wiley   +1 more source

Arachidonic acid metabolism.

open access: yes, 2014
Extracellular milieu; metabolite levels in μM; IR vs. IS; n = 10; (A) 15S-HETE: 15-hydroxy-eicosatetraenoic acid, median test; (B) AA: arachidonic acid, Wilcoxon; (C) DHA: docosahexaenoic acid (Wilcoxon). Horizontal line means grand mean.
Tobias Meile (545989)   +12 more
core   +1 more source

Application, Challenges, and Prospects of Non‐Thermal Processing Technologies for Seaweed Protein Extraction—A Review

open access: yesFood Chemistry International, EarlyView.
This review highlights non‐thermal extraction technologies for seaweed proteins, emphasizing their mechanisms, impacts on protein structure and functionality, and sustainability potential. Key limitations related to species dependence, extract complexity, and scale‐up are discussed to guide future industrial and biorefinery applications.
Rahat Mahmud   +3 more
wiley   +1 more source

The target of arachidonic acid pathway is a new anticancer strategy for human prostate cancer

open access: yes, 2008
Masahide Matsuyama, Rikio YoshimuraDepartment of Urology, Osaka City University Graduate School of Medicine, Osaka, JapanAbstract: Recent epidemiological studies and animal experiments have demonstrated that nonsteroidal anti-inflammatory drugs (NSAIDs ...
Rikio Yoshimura, Masahide Matsuyama
core  

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