Results 91 to 100 of about 122,999 (308)

Process For Producing A Polyunsatured Fatty Acid Comprising Arachidonic Acid (Patent EP 2380984 B1) [PDF]

open access: yes, 2017
The invention relates to nucleic acid derived from Perkinsus marinus which encodes a 9-elongase, a ”8-desaturase and a ”5-desaturase enzyme.
Sayanova, O. V.   +2 more
core  

Arachidonic acid stimulation assays.

open access: yes, 2014
(A) Arachidonic acid stimulation of recombinant HaPP5, MsPP5, and PxPP5 proteins. (B) Responses of crude PPP extracts to arachidonic acid using phosphopeptides as substrate.
Xi’en Chen (563185)   +2 more
core   +1 more source

Evaluation of a pantoprazole and 4‐desmethylpantoprazole‐sulfate metabolic ratio as a novel CYP2C19 phenotyping method

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims CYP2C19 is one of the most important pharmacogenes, and its activity is highly variable due to factors such as genetics or drug–drug interactions. Due to the lack of an appropriate endogenous CYP2C19 biomarker, surrogate methods to assess its activity are warranted.
Julian Peter Müller   +9 more
wiley   +1 more source

Process For The Production Of Arachidonic And/or Eicosapentaenoic Acid (Patent GB 2431158 A)

open access: yes, 2007
A process for the production of arachidonic acid and/or eicosapentaenoic acid in plants through the co-expression of a W -12-/ W -15-desaturase, W -9-elongase, W -8-desaturase and a W -5-desaturase and a process for the production of lipids or oils ...
Sayanova, O. V., Napier, J. A.
core  

Renal tubular arachidonic acid metabolism

open access: yes, 1991
Arachidonic acid and its metabolites play important roles in renal tubular function. This overview will review general characteristics of arachidonic acid metabolism, focus on the characterization and regulation of renal acylhydrolases that generate ...
Bonventre, Joseph V., Nemenoff, Raphael
core   +1 more source

Arachidonic acid binding to CYP168A1.

open access: yes, 2022
Arachidonic acid (10 mg ml-1 in DMF) was progressively titrated against 5 μM CYP168A1 in quartz semi-micro cuvettes of path length 4.5 mm. After each 1 μl addition of arachidonic acid the difference spectrum was measured against a CYP168A1-containing ...
Diane E. Kelly (7585250)   +7 more
core   +1 more source

Deciphering the catalytic and pharmacological mechanisms of Coptis chinensis herbzymes to renovate intestinal microenvironment for colitis alleviation

open access: yesBMEMat, EarlyView.
The synthesized CCzymes possess both antioxidant enzyme activity and pharmacological properties inherent to Coptis chinensis. By their antioxidant enzyme activity, CCzymes can attenuate oxidative stress within the inflammatory region of ulcerative colitis (UC), while their pharmacological activity acts on macrophage polarization and the intestinal ...
Zhichao Deng   +10 more
wiley   +1 more source

Investigation of the effect of glucose syrup and brown sugar as low-cost substrate for lipid production by Mortierella alpine CBS 754.68

open access: yesBiological Journal of Microorganism, 2016
Introduction: Arachidonic acid is an important essential fatty acid in human nutrition. The filamentous fungus Mortierella alpina has been identified as a promising producer of arachidonic acid.
saed Montazeri   +2 more
doaj  

Arachidonic acid matters

open access: yes, 2022
Arachidonic acid ...
GM Turchini (14160615)   +5 more
core  

Nano‐networks via reaction‐induced self‐assembly coordinate spatiotemporal multi‐drug delivery for acute kidney injury therapy

open access: yesBMEMat, EarlyView.
Multifunctional nano‐networks (NNWs) are prepared via reaction‐induced self‐assembly (RISA) of spermidine (SPD), epigallocatechin gallate (EGCG), 2‐formylphenylboronic acid (2‐FPBA), and deferoxamine (DFO) through dynamic iminoboronate bonds. These NNWs leverage the oxidative AKI microenvironment to trigger disintegration, enabling site‐specific ...
Juan Jin   +17 more
wiley   +1 more source

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