Results 131 to 140 of about 104,843 (319)

Research progress of neurovascular units involved in ischemic stroke

open access: yesIbrain, EarlyView.
The brain receives less blood when an ischemic stroke develops, which damages neurons and leads to an increased release of Pro‐inflammatory mediators that activate neurovascular unit (NVU). When the tight junctions are broken and the basement membrane is disrupted by matrix metalloproteinases produced by active endothelial and pericellular cells ...
Yu Yang   +4 more
wiley   +1 more source

Chytrids enhance Daphnia fitness by selectively retained chytrid‐synthesised stearidonic acid and conversion of short‐chain to long‐chain polyunsaturated fatty acids

open access: yesFreshwater Biology, Volume 68, Issue 1, Page 77-90, January 2023., 2023
Abstract Chytrid fungal parasites convert dietary energy and essential dietary molecules, such as long‐chain (LC) polyunsaturated fatty acids (PUFA), from inedible algal/cyanobacteria hosts into edible zoospores. How the improved biochemical PUFA composition of chytrid‐infected diet may extend to zooplankton, linking diet quality to consumer fitness ...
András Abonyi   +4 more
wiley   +1 more source

Integrative cross‐tissue analysis unveils complement‐immunoglobulin augmentation and dysbiosis‐related fatty acid metabolic remodeling during mammalian aging

open access: yesiMeta, EarlyView.
Our study provides a comprehensive multi‐omics profile of aging, integrating proteomic, metabolomic, and metagenomic analyses across diverse tissues and plasma. We identified the synergistic amplification of the circulating complement system and tissue‐wide immunoglobulin accumulation as key molecular drivers of inflammaging.
Feng Zhang   +17 more
wiley   +1 more source

High CX3CR1 expression predicts poor prognosis in paediatric acute myeloid leukaemia undergoing hyperleukocytosis

open access: yesInternational Journal of Laboratory Hematology, Volume 45, Issue 1, Page 53-63, February 2023., 2023
Abstract Introduction Paediatric AML patients with hyperleukocytosis have a poor prognosis and higher early mortality. Therefore, more studies are needed to explore relevant prognostic indicators and develop effective prevention strategies for this type of childhood AML. Methods All original data were obtained from the TARGET database.
Nan Mei   +6 more
wiley   +1 more source

Conversion of eicosapentaenoic acid to chain-shortened omega–3 fatty acid metabolites by peroxisomal oxidation1

open access: yesJournal of Lipid Research, 1998
Human skin fibroblasts can convert arachidonic acid to 14- and 16-carbon polyunsaturated fatty acid products by peroxisomal β-oxidation. The purpose of this study was to determine whether similar products are formed from eicosapentaenoic acid (EPA) and ...
Deborah E. Williard   +3 more
doaj  

Term infant formula macronutrient composition: An update for clinicians

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Protein, carbohydrates, and fats comprise the macronutrient components of infant formulas. While all infant formulas in the United States meet specific nutrition standards, the macronutrient composition of formulas is diverse. Each macronutrient in the formula may play a role in treating or managing the disease.
Catherine Larson‐Nath   +10 more
wiley   +1 more source

Nutraceuticals and COVID‐19: A mechanistic approach toward attenuating the disease complications

open access: yesJournal of Food Biochemistry, Volume 46, Issue 12, December 2022., 2022
Abstract Nutraceuticals have emerged as potential compounds to attenuate the COVID‐19 complications. Precisely, these food additives strengthen the overall COVID treatment and enhance the immunity of a person. Such compounds have been used at a large scale, in almost every household due to their better affordability and easy access.
Keshav Raj Paudel   +19 more
wiley   +1 more source

DGAT‐1 deficiency: Congenital diarrhea and dietary treatment

open access: yesJPGN Reports, EarlyView.
Abstract DGAT‐1 (Diacylglycerol Acyltransferase‐1) deficiency is an autosomal recessive disorder which causes severe impairment in lipid absorption. We report a case of an infant suffering from persistent diarrhea starting at the age of four weeks. Further investigations identified DGAT‐1 deficiency as underlying cause.
Clemens Gardemann   +6 more
wiley   +1 more source

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