Results 141 to 150 of about 189,223 (341)

Stereospecificity of the products of the fatty acid oxygenases derived from psoriatic scales.

Journal of Lipid Research, 1991
The principal in vivo oxygenase products of arachidonic acid and linoleic acid in psoriatic skin scales are 12-hydroxyeicosatetraenoic acid (R/S ratio = 5.7), 13-hydroxyoctadecadienoic acid (S/R = 1.9), and 9-hydroxyoctadecadienoic acid (R/S = 2.4 ...
AN Baer, PB Costello, FA Green
doaj  

Arachidonic acid‐dependent metabolism of 7,8‐dihydroxy‐7,8‐dihydrobenzo[a]pyrene by ram seminal vesicles [PDF]

, 1979
Lawrence J. Marnett, John T. Johnson, Michael J. Bienkowski   +2 more
openalex   +1 more source

Safety and efficacy of docosahexaenoic acid supplementation during neoadjuvant breast cancer therapy: Findings from the phase II, double‐blind, randomized controlled DHA‐WIN trial

International Journal of Cancer, EarlyView.
What's New? Omega‐3 docosahexaenoic acid (DHA) has shown pleiotropic anti‐cancer effects both in vitro and in animal models. However, clinical evidence of DHA efficacy is limited. This randomized, double‐blind, placebo‐controlled trial tested the efficacy of supplementation with DHA 4.4 g/day during 18 weeks of breast cancer neoadjuvant chemotherapy ...
Jaqueline Munhoz, Marnie Newell, Gilbert Bigras, Susan Goruk, Anil Abraham Joy, Sunita Ghosh, Kerry S. Courneya, Vera Mazurak, Claire M. Douglas, Xiaofu Zhu, Bohdarianna Zorniak, John Mackey, Judith Meza Junco, Julie Price Hiller, Karen King, Sanraj K. Basi, Catherine J. Field   +16 more
wiley   +1 more source

EFFECT OF p‐BROMOPHENACYL BROMIDE, AN INHIBITOR OF PHOSPHOLIPASE A₂, ON ARACHIDONIC ACID RELEASE AND PROSTAGLANDIN SYNTHESIS BY THE GUINEA‐PIG UTERUS in vitro [PDF]

, 1977
Sheila M. Mitchell, N.L. Poyser, N.H. Wilson   +2 more
openalex   +1 more source

Alterations and mechanistic insights of gut microbiota and its metabolites in type 2 diabetes mellitus and Alzheimer's disease

iMetaOmics, EarlyView.
This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu, Yu An, Yage Du, Zhaoming Cao, Jie Zheng, Jingya Wang, Tingyi Li, Xingen Lei, Yanhui Lu   +8 more
wiley   +1 more source

Conversion of linoleic acid into arachidonic acid by cultured murine and human keratinocytes

Journal of Lipid Research, 1987
The origin of arachidonic acid (AA) found in the epidermis is not known. Two possibilities exist: either de novo synthesis within the epidermal keratinocyte, or transport of AA formed at distant tissue sites.
R R Isseroff, V A Ziboh, R S Chapkin, D T Martinez   +3 more
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THE ISOLATION OF ARACHIDONIC ACID FROM BRAIN TISSUE

, 1924
Laurence G. Wesson
openalex   +1 more source

Direct inhibition of gastric secretion and mucosal blood flow by arachidonic acid. [PDF]

, 1979
Stanisław J. Konturek, E Mikoś, Wiesław W. Pawlik, Kazimierz M. Walus   +3 more
openalex   +1 more source

Cold atmospheric plasma combined with nanoparticles in cancer therapy

Interdisciplinary Medicine, EarlyView.
Cold atmospheric plasma (CAP) generates a range of reactive oxygen and nitrogen species (RONS), including singlet oxygen (1O2), hydrogen peroxide (H2O2), hydroxyl radicals (·OH), nitrate (NO3− ${{\text{NO}}_{3}}^{-}$), and nitrite (NO2− ${{\text{NO}}_{2}}^{-}$), which induce oxidative stress and apoptosis in cancer cells.
Yunhao Wang, Fei Cao, Gbenga A. Martins, Qiujie Fang, Yifan Lin, Zhaowei Chen, Guojun Chen, Zhitong Chen   +7 more
wiley   +1 more source

Deletion of ELOVL5 leads to fatty liver through activation of SREBP-1c in mice*[S]

Journal of Lipid Research, 2009
Elongation of very long chain fatty acids (ELOVL)5 is one of seven mammalian fatty acid condensing enzymes involved in microsomal fatty acid elongation. To determine the in vivo substrates and function of ELOVL5, we generated Elovl5−/− mice.
Young-Ah Moon, Robert E. Hammer, Jay D. Horton   +2 more
doaj