Results 161 to 170 of about 122,999 (308)

Seminal Plasma Exosomal miRNA Profiling Reveals hsa‐miR‐7‐5p as a Key Regulator of Sperm Motility in Asthenozoospermia

open access: yesAndrology, EarlyView.
ABSTRACT Background Asthenozoospermia is a significant contributing factor to male infertility. Accumulating evidence indicates that impaired sperm motility is closely linked to dysregulated microRNA expression during spermatogenesis. Seminal plasma exosomes are enriched with diverse microRNAs, which play pivotal roles in modulating sperm motility, the
Zhi‐Jian Zhu   +8 more
wiley   +1 more source

Arachidonic acid enrichment of rotifers and effects of dietary arachidonic acid on broodstock performance of rabbitfish Siganus guttatus

open access: yes, 2006
Rotifers (Brachionus sp.) were cultured with various combinations of baker’s yeast, Nannochloropsis sp., Culture selco, and DHAPS with or without supplementation of arachidonic acid (triacylglycerol form).
Tibubos, Keneth R.   +4 more
core  

Xiebai San Alleviates Allergic Pulmonary Inflammation by Modulating Arachidonic Acid Metabolism. [PDF]

open access: yesPharmaceuticals (Basel)
Yue X   +10 more
europepmc   +1 more source

The role of the arachidonic acid pathway in NSCLC development and progression : novel approaches for therapeutic intervention

open access: yes, 2013
Arachidonic acid metabolism through cyclooxygenase (COX), lipoxygenase (LOX) and cytochrome P-450 epoxygenase (EPOX) pathways is responsible for the formation of biologically active eicosanoids, including prostanoids, leukotrienes ...
Pidgeon, Graham P.   +2 more
core  

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

open access: yesBritish Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli   +7 more
wiley   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

MCL1 promotes porcine epidemic diarrhea virus replication by modulating arachidonic acid metabolic pathway. [PDF]

open access: yesPLoS Pathog
Shang H   +13 more
europepmc   +1 more source

Covalent fluorescent probes for 2‐arachidonoylglycerol metabolic pathways

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Covalent fluorescent probes have emerged as versatile chemical tools to visualise active enzymes in complex biological systems. When tailored for specific applications, ranging from activity‐based protein profiling for drug development to high spatiotemporal resolution imaging of enzymatic activities, these probes provide unique insights into ...
Nick D. F. Puijmbroeck   +1 more
wiley   +1 more source

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