Results 161 to 170 of about 2,614,074 (305)

PFOA Exposure Elicits Quantitative Lipidomic Changes in the Pancreas in a Mouse Model of Pancreatic Cancer

Environmental Toxicology, EarlyView.
ABSTRACT Pancreatic cancer is the fourth leading cause of cancer deaths in the US and predicted to rise to second by 2030. Several risk factors have been identified as potential contributors to pancreatic cancer development including lifestyle factors and long‐term exposure to occupational and environmental carcinogens.
Barbara A. Hocevar, Lisa M. Kamendulis
wiley   +1 more source

CP1Hao Decoction Alleviates Chronic Prostatitis by Modulating Arachidonic Acid Metabolism: A Multi-Omics Analysis. [PDF]

Am J Mens Health
Lei LX, Chang HR, Feng JL, Xia Y, Chen H, Lin XF, Li KC, Sun LJ, Wang L, Wang JS.   +9 more
europepmc   +1 more source

Research Progress on Upper Airway Cough Syndrome

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Upper airway cough syndrome (UACS) has been identified as a significant contributor to chronic cough in various national guidelines. However, the complexity of its pathogenesis, the lack of clarity surrounding its diagnostic criteria, and its overlap with other etiologies of chronic cough present considerable challenges in both diagnosis and ...
Wan‐Ting Huang, Jia Chen
wiley   +1 more source

Inhibition of COX-2-Mediated Arachidonic Acid Metabolism by FGF21-PPARα Axis Alleviates Liver Steatosis. [PDF]

MedComm (2020)
Xu G, Pan T, Wang G, Qiu F, Leng J, Feng Q, Xue Y, Wang Y, Zheng J, Lu H, Han B, Wang S, Du J, Lv J, Wang B, Pan X.   +15 more
europepmc   +1 more source

Kaempferol Protects Intestinal Health in Chinese Forest Musk Deer Possibly by Regulating Intestinal Microbiota and Inhibiting the NF‐κB/NLRP3 Signaling Pathway

Integrative Zoology, EarlyView.
Kaempferol modulates the tryptophan metabolism pathway by increasing the abundances of Christensenellaceae R7 group, Bacteroides, and Blautia and reducing that of Rikenellaceae RC9 gut group, thereby significantly increasing the levels of ILA and IAA. This process inhibits the activation of NF‐κB/NLRP3 signaling pathway, reduces pro‐inflammatory factor
Xiangyu Liu, Zhanjun Ren, Xiuzhu Sun, Shuhui Wang   +3 more
wiley   +1 more source

Serum Palmitoleic Acid and Arachidonic Acid as a Noninvasive Screening Tool for Endometrial Cancer. [PDF]

Cancers (Basel)
Yamazaki N, Katoh Y, Kubo A, Sugawara M, Otsuka Y, Ogawa T, Fukuta M, Suzuki K, Wakai K, Fujii Y, Hirai S.   +10 more
europepmc   +1 more source

Metabolome Diversity Enhances Resistance of Intertidal Clams to Thermal Stress

Integrative Zoology, EarlyView.
Meretrix species are widely distributed intertidal bivalves in China with significant ecological and economic importance, which are sensitive to thermal stress. Our results showed that thermal environments of clam habitats shaped metabolome diversity, which can enhance the resistance of intertidal clams to thermal stress.
Zhi Hu, Xiang‐Tao Wei, Xiaonie Lin, Linxuan Ma, Tianzhe Zhang, Yunwei Dong   +5 more
wiley   +1 more source

ASGR1 Deficiency Promotes Liver Fibrosis by Enhancing Pro-Inflammatory Arachidonic Acid Metabolism and ALP Secretion. [PDF]

Immun Inflamm Dis
Zhu H, Huang XP, You K, Chen Y, Li PH, Tao JW, Yu XR, Xu JH, Xu GS, Li YX.   +9 more
europepmc   +1 more source

Association Characteristics and Potential Mechanisms of Aging, Gut Microbiota, and Hearing Loss

Integrative Zoology, EarlyView.
The study found that aging leads to unchanged gut microbiota alpha diversity but an increase in Bacteroidetes and a decrease in Firmicutes at the phylum level, with specific genera, species, and functional pathways co‐associated with aging and hearing loss. Through constructing a microbe‐metabolite network, it revealed the mechanism by which protective
Cheng Cheng, Lu Wang, Runhan Li, Wenkai Lai, Chongkui Sun, Jianguo Cui, Bicheng Zhu, Jiang Zhang   +7 more
wiley   +1 more source

Microbiota-Dependent Alleviation of Ulcerative Colitis by Liubao Tea: Integrated Insights into SCFA and Arachidonic Acid Metabolism. [PDF]

Foods
Yang X, Xu S, Tong Y, Luo J, Fang X, Du J, Zhou C, Hu G, Yang B, Zhang Q.   +9 more
europepmc   +1 more source