Results 171 to 180 of about 183,297 (300)

Pharmacokinetics and Anti‐Inflammatory Effects of Intramuscular Betamethasone in Exercised Thoroughbred Horses

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The pharmacokinetics and pharmacodynamics of betamethasone following intra‐articular administration to horses have been described; however, studies characterizing intramuscular administration are lacking. Twenty‐four horses received an intramuscular dose of 12 mg betamethasone sodium phosphate/betamethasone acetate.
Juliana Sullivan, Jeff Blea, Daniel S. McKemie, Philip H. Kass, Heather K. Knych   +4 more
wiley   +1 more source

LncRNA TLR8-AS1 Restricts HIV-1 Infection and Inflammation in Macrophages by Suppressing Arachidonic Acid Metabolism Through NFAT1. [PDF]

J Inflamm Res
Wang F, Luo S, Zhang J, Zhang Y, Wei H, Liu J, Mo C, Jiang J, Ye L, Yuan Z.   +9 more
europepmc   +1 more source

Macronutrient composition in pollen affects development and survival in wild bees

Physiological Entomology, EarlyView.
Small carpenter bees (Ceratina calcarata) were reared on diets formulated with black poplar and dandelion pollen, while closely monitoring developmental metrics, lipid content and survival. Macronutrient analyses on both pollen types revealed dandelion pollen contained lower levels of protein, essential amino acids and several fatty acids, which ...
Khara W. Stephen, Sandra M. Rehan
wiley   +1 more source

Arachidonic acid induces pyroptosis via a non-autophagic function of mitophagy and enhances immunotherapy in a PDAC model. [PDF]

Nat Commun
Chu T, Liu Z, Liu H, Mu W, Zhi Y, Sheng N, Zhang J, Peng X, Lv S, Duan K, Lou F, Liu H, Wang C, Zhou J, Liu X, Yang H, Liu Y, Xu J, Fan Z, Wei F.   +19 more
europepmc   +1 more source

Therapeutic effect of NEO400, perillyl alcohol conjugated to linoleic acid, in a mouse model of UV‐induced skin damage

Photochemistry and Photobiology, Volume 101, Issue 2, Page 338-349, March/April 2025.
In the present work with mouse models, we demonstrate that a novel compound, NEO400, is able to profoundly protect skin against damage caused by UV radiation (UVR) when it is applied to skin post‐UVR exposure. In comparison, Aloe vera or linoleic acid are unable to achieve a similar level of protection.
Stephen Swenson, Catalina Silva‐Hirschberg, Liliana Freeland, Kristen L. Chen, Nagore I. Marín‐Ramos, Axel H. Schönthal, Thomas C. Chen   +6 more
wiley   +1 more source

Hydroxytyrosol Modulates Arachidonic Acid Metabolism and Purine Catabolism in Individuals with Prediabetes: An Untargeted Metabolomics Study in a Randomized Controlled Trial. [PDF]

Antioxidants (Basel)
Moratilla-Rivera I, Fernández-Millán E, Pérez-Jiménez J, Ramos S, Yanes Ó, Capellades J, Mateos R, Martín MÁ.   +7 more
europepmc   +1 more source

Alleviation of photoaging‐associated MMP upregulation, prostanoid biosynthesis, and cell cycle arrest with titanium dioxide, zinc oxide, and inorganic‐only (ZnO + TiO2) sunscreens

Photochemistry and Photobiology, EarlyView.
Inorganic sunscreens containing the UV filters titanium dioxide (TiO2) and/or zinc oxide (ZnO) alleviated various biomarkers of photoaging in human dermal fibroblasts, at a gene and protein level. The study provides novel insights that observe the impact of inorganic photoprotection through the molecular biology of skin.
Neil Dominic T. Pangilinan, Mohammad Shalbaf, Aline Souza, Bhaven Chavan, Mark A. Birch‐Machin   +4 more
wiley   +1 more source

Crosstalk between arachidonic acid metabolism and glycolysis drives integrated metabolic-inflammatory reprogramming in macrophages. [PDF]

Int J Biol Sci
Cheng Y, Fan N, Zhang X, Zhao W, Xie B, Zhao J, Rong M, Li X, Tse HF, Rong J.   +9 more
europepmc   +1 more source

Arachidonic Acid Measurement [PDF]

, 2020
openaire   +1 more source

Transcriptional benchmark dose modeling of ultraviolet radiation‐induced genomic activation in mouse skin

Photochemistry and Photobiology, EarlyView.
Exposure to ultraviolet radiation (UV‐R) from tanning equipment increases skin cancer risk through molecular changes, but genomic thresholds remain unclear. Using mice, we examined dose‐ and time‐dependent gene expression after erythemally‐weighted UV‐R doses (0–40 mJ/cm2).
Sami S. Qutob, Samantha P. M. Roesch, Sandy Smiley, Pascale V. Bellier, Andrew Williams, Kate B. Cook, Matthew J. Meier, Andrea Rowan‐Carroll, Carole L. Yauk, James P. McNamee, Vinita Chauhan   +10 more
wiley   +1 more source