Background Lipoxygenases (LOX) play pivotal roles in the biosynthesis of leukotrienes and other biologically active potent signalling compounds. Developing inhibitors for LOX is of high interest to researchers.
Khosravi Ebrahim+2 more
doaj +1 more source
Specific Inhibition of the Polymorphonuclear Leukocyte Chemotactic Response to Hydroxy-Fatty Acid Metabolites of Arachidonic Acid by Methyl Ester Derivatives [PDF]
Edward J. Goetzl+3 more
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Stereospecificity of the products of the fatty acid oxygenases derived from psoriatic scales.
The principal in vivo oxygenase products of arachidonic acid and linoleic acid in psoriatic skin scales are 12-hydroxyeicosatetraenoic acid (R/S ratio = 5.7), 13-hydroxyoctadecadienoic acid (S/R = 1.9), and 9-hydroxyoctadecadienoic acid (R/S = 2.4 ...
AN Baer, PB Costello, FA Green
doaj
EFFECT OF p‐BROMOPHENACYL BROMIDE, AN INHIBITOR OF PHOSPHOLIPASE A2, ON ARACHIDONIC ACID RELEASE AND PROSTAGLANDIN SYNTHESIS BY THE GUINEA‐PIG UTERUS in vitro [PDF]
Sheila M. Mitchell+2 more
openalex +1 more source
The structure of arachidonic and linoleic acids [PDF]
C. L. Arcus, Ida Smedley-Maclean
openaire +3 more sources
Cold EI—The Way to Improve GC‐MS and Increase Its Range of Applications
ABSTRACT Gas chromatography‐mass spectrometry (GC‐MS) with Cold electron ionization (EI) is based on interfacing the GC and MS with a supersonic molecular beam (SMB) along with electron ionization of vibrationally cold sample compounds in the SMB in a contact‐free fly‐through ion source (hence the name Cold EI).
Aviv Amirav+3 more
wiley +1 more source
The role of the host—Neutrophil biology
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple+4 more
wiley +1 more source
Conversion of linoleic acid into arachidonic acid by cultured murine and human keratinocytes
The origin of arachidonic acid (AA) found in the epidermis is not known. Two possibilities exist: either de novo synthesis within the epidermal keratinocyte, or transport of AA formed at distant tissue sites.
R R Isseroff+3 more
doaj
CL regression in the pseudopregnant rabbit and the effects of treatment with prostaglandin F-2 and arachidonic acid [PDF]
John C. Carlson, J.W.D. Gole
openalex +1 more source