Results 231 to 240 of about 104,843 (319)

Arachidonic acid is involved in high-salt diet-induced coronary remodeling through stimulation of the IRE1α/XBP1s/RUNX2/OPN signaling cascade. [PDF]

Lipids Health Dis
Jia Z, Wu J, Liu F, Wang H, Zheng P, Shen B, Zhao R.   +6 more
europepmc   +1 more source

Altered renal and platelet arachidonic acid metabolism in cirrhosis

, 1986
Giacomo Laffi, Giorgio La Villa, Massimo Pinzani, Giovanni Ciabattoni, Paola Patrignani, Massimo Mannelli, Fabio Cominelli, Paolo Geñtilini   +7 more
openalex   +1 more source

Arachidonic acid and infant formulas [PDF]

Pediatric Research, 2015
openaire   +3 more sources

Intestinal Dysmotility and Associated Disorders in Intestinal Muscle of Methylglyoxal‐Treated Mice

Neurogastroenterology &Motility, EarlyView.
In patients undergoing long‐term peritoneal dialysis, intestinal transit capacity is often impaired, though the underlying mechanism remains unclear. Using a mouse model, we identified inflammation and impairment of interstitial cells of Cajal (ICC) in intestinal smooth muscle as potential contributors to this reduced transit capacity.
Yuki Yamakawa, Taiki Mihara, Masatoshi Hori   +2 more
wiley   +1 more source

Carthamus tinctorius L. protects cerebral ischemia/reperfusion injury via arachidonic acid/p53-mediated apoptosis axis. [PDF]

Front Pharmacol
Chen J, Wu L, Xie X, Peng C.
europepmc   +1 more source

Leukotriene formation by a purified reticulocyte lipoxygenase enzyme. Conversion of arachidonic acid and 15-hydroperoxyeicosatetraenoic acid to 14, 15-leukotriene A4.

, 1985
Robert W. Bryant, T Schewe, S. Rapoport, Jennifer M. Bailey   +3 more
openalex   +1 more source

Insulin resistance, overweight, and obesity in apheresis donors: A call to reevaluate their eligibility—A prospective cohort study

Transfusion, EarlyView.
Abstract Background Apheresis procedures and the infusion of acid‐citrate‐dextrose induce metabolic alterations that may influence glucose metabolism. Although insulin resistance (IR), overweight, and obesity are not exclusion criteria for blood donation, their impact during apheresis procedure and on post‐donation metabolic responses remains ...
Edgar Barrientos‐Galeana, Gabriela Chico‐Barba, Mari Cruz Tolentino‐Dolores, Emmanuel Fernández‐Sánchez, Rosa María Morales‐Hernández, Selene Barragán‐Montes, Maria de los Angeles Rosales‐López, Raymundo Rodríguez‐Jurado, Ángel Sebastián Quebrado‐Benítez, María‐Cristina Ramírez‐González, Heriberto López‐Martínez, Noemi Hernández‐Cruz, Jannyn Herrera‐Juárez, Karla Eugenia Bermúdez‐Ferro, Rodrigo Castillo‐Llanos   +14 more
wiley   +1 more source

Role of arachidonic acid in ischemic heart disease under different comorbidities: risk or protection? [PDF]

Cardiovasc Diabetol
Li C, Chen H.
europepmc   +1 more source

Effects of acute selective cyclooxygenase‐2 inhibition on skeletal muscle microvascular oxygenation and exercise tolerance

Experimental Physiology, EarlyView.
Abstract The cyclooxygenase (COX) pathway regulates vascular tone and, therefore, local O2 delivery‐utilization matching. The two main isoforms, COX‐1 and COX‐2, may promote opposing effects on contracting muscle O2 transport in health by inducing vasoconstriction and vasodilatation, respectively.
Michael D. Belbis, Michael J. Holmes, Joseph Yao, Christopher W. Kinnick, Christopher K. Kargl, Carly Day, Nicole L. Noel, Timothy P. Gavin, Bruno T. Roseguini, Daniel M. Hirai   +9 more
wiley   +1 more source

LIBX‐A401: A Novel Selective Inhibitor of Acyl‐CoA Synthetase Long Chain Family Member 4 (ACSL4) and Its Binding Mode

Angewandte Chemie, Volume 137, Issue 19, May 5, 2025.
The discovery of LIBX‐A401, a potent and selective ACSL4 inhibitor derived from rosiglitazone is reported. HDX‐MS reveals that LIBX‐A401 stabilizes the ACSL4 C‐terminus and alters the fatty acid (FA) gate domain. Consistently, photoaffinity labeling, molecular dynamics, and mutagenesis identify key binding residues within the FA pocket.
Darius Mazhari Dorooee, Séverine Ravez, Didier Vertommen, Nicolas Renault, Nicolas Papadopoulos, Romain Marteau, Emeline Charnelle, Karine Porte, Alexandre Gobert, Nathalie Hennuyer, Gaetan Herinckx, Maëla Pautric, Aurélie Jonneaux, Jean Christophe Devedjian, David Devos, Bart Staels, Patricia Melnyk, Stefan N. Constantinescu, Raphaël Frédérick, Jamal El Bakali   +19 more
wiley   +2 more sources