Results 251 to 260 of about 2,614,074 (305)

[In and around a cascade of arachidonic acid].

Nihon Kyobu Shikkan Gakkai zasshi, 1987
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Arachidonic acid induces pyroptosis via a non-autophagic function of mitophagy and enhances immunotherapy in a PDAC model. [PDF]

Nat Commun
Chu T, Liu Z, Liu H, Mu W, Zhi Y, Sheng N, Zhang J, Peng X, Lv S, Duan K, Lou F, Liu H, Wang C, Zhou J, Liu X, Yang H, Liu Y, Xu J, Fan Z, Wei F.   +19 more
europepmc   +1 more source

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Arachidonic Acid Derivatives and Neuroinflammation

CNS and Neurological Disorders - Drug Targets, 2022
: Neuroinflammation is characterized by dysregulated inflammatory responses localized within the brain and spinal cord. Neuroinflammation plays a pivotal role in the onset of several neurodegenerative disorders and is considered a typical feature of these disorders.
Vincenzo Calderone, Era Gorica
exaly   +3 more sources

ARACHIDONIC ACID METABOLISM

Annual Review of Biochemistry, 1986
C YC LOO XYGENASE PRODUC TS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . . . . . . . 70 Prostaglandin Endoperoxide Synthase 70 Metabolism of the Prostaglandin Endoperoxides 71 P RODUC TS OF THE 12-LIPO XYGEN ASE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
P, Needleman, J, Turk, B A, Jakschik, A R, Morrison, J B, Lefkowith   +4 more
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Arachidonic acid metabolism

Preventive Medicine, 1987
Arachidonic acid metabolites can act as tumor promoters and can affect growth and metastases of tumors in three ways: (a) Prostacyclin inhibits and thromboxane facilitates platelet-tumor cell interactions and, thereby, tumor cell invasiveness; (b) the cytoprotective action of prostaglandins contributes to epithelial cell integrity and influences tissue
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Arachidonic acid production by microorganisms

Biotechnology and Applied Biochemistry, 1992
Arachidonic acid (AA) is a natural precursor of prostaglandins, thromboxanes, leukotrienes, prostacyclins, and a large group of C20 compounds which are of intrinsic medical interest. At present, the only source of AA is animal tissues. However, it is present in several microorganisms. This review describes the production of AA by microorganisms and its
P, Bajpai, P K, Bajpai
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Prostaglandins, Arachidonic Acid, and Inflammation

Science, 1980
The enzymatic oxidation of arachidonic acid has been shown to yield potent pathological agents by two major pathways. Those of the prostaglandin (PG) pathway, particularly PGE2, have been implicated as inflammatory mediators for many years. The discovery and biological activities of thromboxane A2and prostacyclin as well as a destructive oxygen ...
F A, Kuehl, R W, Egan
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Biological Nitration of Arachidonic Acid

Current Vascular Pharmacology, 2004
When a spontaneous autoxidation of arachidonic acid to prostaglandin-like products was first described almost 40 years ago, it was thought to be an artifact that interfered with the detection of enzymatically generated prostaglandins. It has now been generally accepted that the autoxidation of arachidonic acid occurs in vivo and leads to formation of ...
Michael, Balazy, Candace D, Poff
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Glucagon and plasma arachidonic acid

Metabolism, 1965
Abstract Previous work has shown the presence of a factor in the external pancreatic secretion of dogs distinct from the enzymes that affect plasma arachidonic acid. Removal of the exocrine factor by pancreatectomy or pancreatic duct ligation resulted in depression of arachidonic acid in all plasma lipid fractions which could not be corrected by ...
R, CAREN, L, CORBO
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Renal Arachidonic Acid Metabolism

Annual Review of Physiology, 1984
Renal prostaglandin synthesis has been the focus of extensive investigation during the past decade. This chapter reviews the cellular localization of renal arachidonic acid metabolism in view of the substantial recent progress in the isolation and culture of renal cell types.
M G, Currie, P, Needleman
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