Results 241 to 250 of about 122,999 (308)

KIF18A induces the EMT process of hepatoma cells through the 5-LOX-dependent arachidonic acid pathway. [PDF]

PLoS One
Wang Y, Cai T, Chen Y, Liu W, Liu B, Zhao X, Wang Y, Cao J, Zeng Q.   +8 more
europepmc   +1 more source

Integrated Single‐Cell RNA Sequencing and Untargeted Metabolomics Reveals β‐Elemene's Immune and Metabolic Modulation in Triple‐Negative Breast Cancer

MedComm – Oncology, Volume 5, Issue 3, September 2026.
In a 4T1 TNBC model, β‐elemene suppressed tumor growth and pulmonary metastasis. scRNA‐seq showed it remodeled the tumor microenvironment by reducing cancer‐associated fibroblasts, enhancing antigen presentation, and inhibiting pro‐tumorigenic ECM remodeling. Metabolomics revealed prostaglandin downregulation.
Zhiqiang Luo, Guohua Yu, Huixia Fan, Ruofan Guo, Jingqi Zheng, Chen Wang, Ruyi Jin, Junhui Zhou, Jian Yang   +8 more
wiley   +1 more source

Prevotella copri alleviates diarrhea in weaning piglets through gut microbiota modulation and arachidonic acid-AHR-NRF2 pathway activation. [PDF]

J Anim Sci Biotechnol
Lan C, Ren W, Wu A, Yu B, He J, Luo Y, Chen D.   +6 more
europepmc   +1 more source

Physical Activity and Metabolic Alterations in Children and Adolescents Across Different Weight Groups: A Systematic Review

European Journal of Sport Science, Volume 26, Issue 7, July 2026.
ABSTRACT Inadequate physical activity (PA) and increased sedentary time are key drivers of cardiometabolic disorders related to being overweight, and metabolomics offers a promising novel approach to study their associations. The aim of this systematic review was to assess the evidence on metabolites associated with PA and/or sedentary time among ...
Marja H. Leppänen, Jukka E. Hintikka, Kathleen Wijnant, Eero A. Haapala, Timo A. Lakka, Lynn Vanhaecke, Heli Viljakainen   +6 more
wiley   +1 more source

Pre-activation of T cell immunity potentiates ferroptotic cell death through arachidonic acid hybridized nanovesicles. [PDF]

J Nanobiotechnology
Lyu Q, Liu C, Li S, Shan D, Han H, Wang L, Xu H.   +6 more
europepmc   +1 more source

Scutellarein Alleviates Ulcerative Colitis by Reshaping Gut Microbiota and Regulating the PRMT1‐Mediated Th17/Treg Balance

Food Frontiers, Volume 7, Issue 4, July 2026.
Scutellarein alleviates ulcerative colitis by reinforcing the intestinal barrier via the microbiota‐metabolite axis and suppressing PRMT1‐STAT3‐mediated inflammatory immune responses. ABSTRACT Ulcerative colitis (UC) is a chronic inflammatory disease of the colonic mucosa with an increasing global burden and limited therapeutic efficacy.
Yefan Zhou, Xinyu Xu, Huan Fang, Xue Wang, Jiaqi Hua, Linping Lu, Dongxu Li, Yangyang Wen, Jieqiong Yao, Fang Liu, Jing He, Fucheng He, Mingxia Zhou   +12 more
wiley   +1 more source

Tumoral ALOX5 mediated arachidonic acid metabolism regulates immune response in non-small cell lung cancer. [PDF]

Cell Oncol (Dordr)
Gao Y, Xia Y, Li J, Lai Y, Yin S, Lin J, Yu D, Huang S, Lu F, Wang W, Chu Q.   +10 more
europepmc   +1 more source

Acute High-Intensity Noise Exposure Induces Cognitive Impairment and Arachidonic Acid Metabolism-Related Molecular Alterations in Rats: A Multi-Omics Study. [PDF]

Metabolites
Liu Y, Diao M, Hao Y, Liu Z, Ma H, Zou Y, Ma L, Wang L, Zhi W, Yu Q.   +9 more
europepmc   +1 more source

<i>Faecalibacterium prausnitzii</i> ameliorates sepsis-induced acute lung injury via gut-lung axis by regulating arachidonic acid-LXA4-Nrf2-HO-1 pathway and restoring gut microecology. [PDF]

Front Microbiol
Feng X, Xu P, Li H, Peng L, Li S, Ma J, Ma J, Ma Z, Ma L, Li K, Ma T, Yu J, Ma X, Ma S, Zhang X, Wang H, Yang X.   +16 more
europepmc   +1 more source