Results 261 to 270 of about 194,523 (350)

Mechanisms of Action Involved in the In Vivo Gastroprotective Response of Fruits: A Systematic Review

open access: yesFood Frontiers, Volume 7, Issue 1, January 2026.
ABSTRACT Gastrointestinal diseases remain a significant global health concern, primarily due to the limitations of current pharmacological treatments, which often come with adverse side effects and high recurrence rates. This situation highlights the urgent need for safer and more effective alternatives.
Isabel Sousa Alcântara   +7 more
wiley   +1 more source

Modulators of Diacylglycerol Kinase Activity: A Review of Advances and Challenges

open access: yesMedicinal Research Reviews, Volume 46, Issue 1, Page 149-175, January 2026.
ABSTRACT Catalyzing the conversion of diacylglycerol (DAG) in phosphatidic acid (PA), diacylglycerol kinases (DGKs) play a pivotal role in all the physiological processes modulated by these two bioactive lipids, such as lipid metabolism and immune regulation.
Luisa Racca   +2 more
wiley   +1 more source

The physiological and pathological effects of sphingolipid metabolism and signaling in the central nervous system

open access: yesBrain Pathology, Volume 36, Issue 1, January 2026.
Sphingolipids are vital components of cell membranes. Metabolic disruptions of sphingolipids, including ceramide and sphingosine‐1‐phosphate, are linked to neurological disorders. This article summarizes the classification, structure, and metabolic processes of sphingolipids, and the physiological and pathological effects of sphingolipid metabolism and
Tian Li   +7 more
wiley   +1 more source

Dendritic Cell Migration: An Essential Step in Initiating Adaptive Immunity Across Tissues

open access: yesImmunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT Immune surveillance of tissues is primarily carried out by dendritic cells (DCs), which act as sentinels for the adaptive immune system. To accomplish this task, DCs migrate from tissues to regional lymph nodes, or from blood‐exposed regions of the spleen to the white pulp, to prime T cell responses. DC migration is a tightly regulated process
Eli C. Olson   +2 more
wiley   +1 more source

TEG platelet mapping and impedance aggregometry to predict platelet transfusion during cardiopulmonary bypass in pediatric patients [PDF]

open access: yes, 2019
Baltagi, Sirine   +6 more
core   +1 more source

Mechanosensing in Dendritic Cells

open access: yesImmunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT Since their discovery, dendritic cells have been recognized for their unusual capacity to sense and respond to physical stimuli within their environment. However, it took nearly two decades—and the advent of mechanobiology—to elucidate the underlying mechanisms and functional implications of this mechanical hypersensitivity. In this review, we
Vincent Calmettes   +5 more
wiley   +1 more source

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