Results 271 to 280 of about 187,350 (364)

ACSM5 Regulates Ferroptosis in Hepatocellular Carcinoma by Up‐Regulating POR and Modulating Lipid Metabolism

open access: yesCancer Science, EarlyView.
ACSM5 induced ferroptosis in HCC by up‐regulating cytochrome P450 oxidoreductase (POR). The metabolic transformation of linoleic acid to arachidonic acid was also promoted by ACSM5; thereby, the sensitivity to ferroptosis was elevated. ABSTRACT The medium‐chain fatty acyl‐CoA synthetase‐5 (ACSM5) plays a crucial role in the development of some cancers.
Zhengqiang Wu   +8 more
wiley   +1 more source

A Survey of Fatty Acid Content of the Male Reproductive System in Mice Supplemented With Arachidonic Acid. [PDF]

open access: yesJ Lipids
Correa-Navarro VA   +7 more
europepmc   +1 more source

Analysis of arachidonic acid metabolites in the BALF of patients with bronchial asthma.

open access: bronze, 1989
Jun Kobayashi   +4 more
openalex   +2 more sources

TRIM21 Promotes Tumor Growth and Gemcitabine Resistance in Pancreatic Cancer by Inhibiting EPHX1-Mediated Arachidonic Acid Metabolism. [PDF]

open access: yesAdv Sci (Weinh)
Fan X   +15 more
europepmc   +1 more source

GPD1L‐Mediated Glycerophospholipid Metabolism Dysfunction in Women With Diminished Ovarian Reserve: Insights From Pseudotargeted Metabolomic Analysis of Follicular Fluid

open access: yesCell Proliferation, EarlyView.
Our study demonstrated the downregulation of GPD1L and its mediated glycerophospholipid metabolism dysfunction in patients with diminished ovarian reserve. Moreover, we verified that GPD1L knockdown leads to increased cell apoptosis and mitochondrial dysfunction of KGN cells, as well as impaired oocyte quality.
Jiaqi Wu   +8 more
wiley   +1 more source

Long‐term fasting induces a remodelling of fatty acid composition in erythrocyte membranes

open access: yesEuropean Journal of Clinical Investigation, Volume 55, Issue 5, May 2025.
Abstract Introduction Long‐term fasting (LF) activates an adaptative response to switch metabolic fuels from food glucose to lipids stored in adipose tissues. The increase in free fatty acid (FFA) oxidation during fasting triggers health benefits. We questioned if the changes in lipid metabolism during LF could affect lipids in cell membranes in humans.
Katharina Gewecke   +5 more
wiley   +1 more source

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