Cyclosporin A inhibits PGE2 release from vascular smooth muscle cells [PDF]
, 1987 The influence of the fungoid undecapeptide cyclosporin A (CyA) on PGE2 release from cultured rat aortic smooth muscle cells was investigated in this study.
Koch, K. M. +3 more
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Arachidonic acid enhances turnover of the dermal skeleton: studies on zebrafish scales.
PLoS ONE, 2014 In fish nutrition, the ratio between omega-3 and omega-6 poly-unsaturated fatty acids influences skeletal development. Supplementation of fish oils with vegetable oils increases the content of omega-6 fatty acids, such as arachidonic acid in the diet ...
Erik de Vrieze +4 more
doaj +1 more source
Modulation of guanosine triphosphatase activity of G proteins by arachidonic acid in rat Leydig cell membranes [PDF]
, 2000 Previous results from our group have indicated that arachidonic acid decrease cAMP production through a modification of heterotrimericGproteins.\ud In the present study, we have characterized the high affinity GTPase activity present in Leydig cell ...
Colás Escudero, Begoña +4 more
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Arachidonic acid-induced release of calcium in permeabilized human neutrophils [PDF]
, 1987 The addition of arachidonic acid to a suspension of digitonin-permeabilized human neutrophils was found to induce, in a dose-dependent manner (ED50 about 15 μM), the release of calcium from internal stores.
Beaumier, L. +2 more
core +1 more source
Basal and inducible anti-inflammatory epoxygenase activity in endothelial cells [PDF]
, 2014 The roles of CYP lipid-metabolizing pathways in endothelial cells are poorly understood. Human endothelial cells expressed CYP2J2 and soluble epoxide hydrolase (sEH) mRNA and protein.
Ara A. Askari +35 more
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Arachidonic Acid and the Brain [PDF]
The Journal of Nutrition, 2008 Kinetic methods in unanesthetized rodents have shown that turnover rates of arachidonic acid (AA) and docosahexaenoic acid (DHA) in brain membrane phospholipids are rapid and energy consuming and that phospholipase A(2) (PLA(2)) and acyl-CoA synthetase enzymes that regulate turnover are specific for one or the other PUFA.
openaire +3 more sources
CYP-omega-hydroxylation-dependent metabolites of arachidonic acid inhibit the basolateral 10pS chloride channel in the rat thick ascending limb [PDF]
, 2009 Metabolites of arachidonic acid influence sodium chloride (NaCl) transport in the thick ascending limb. Because a 10pS Cl channel is the major type of chloride channel in the basolateral membrane of this nephron segment, we explored the effect of ...
Gu, Feng +12 more
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Arachidonic acid in cell signaling [PDF]
Current Opinion in Cell Biology, 1993 Important advances have recently been made in our understanding of the arachidonic acid cascade. The molecular characterization of different forms of phospholipase A2 indicates that multiple pathways are involved in the release of arachidonic acid evoked by physiological or pathological stimuli.
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Mediators of Inflammation, 2000 The effect of various phospholipase A2 and protein kinase inhibitors on the arachidonic acid liberation in bovine platelets induced by the protein kinase activator 12-O-tetradecanoylphorbol–13-acetate (TPA) was studied.
M. Lehr, K. Griessbach
doaj +1 more source
Production of a soluble and functional recombinant apolipoproteinD in the Pichia pastoris expression system [PDF]
, 2016 ApolipoproteinD (ApoD) is a human glycoprotein from the lipocalin family. ApoD contains a conserved central motif of an 8-stranded antiparallel β-sheet, which forms a beta-barrel that can be used for transport and storage of diverse hydrophobic ligands ...
Armanmehr, S. +2 more
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