Results 21 to 30 of about 189,223 (341)
Production of a soluble and functional recombinant apolipoproteinD in the Pichia pastoris expression system [PDF]
, 2016 ApolipoproteinD (ApoD) is a human glycoprotein from the lipocalin family. ApoD contains a conserved central motif of an 8-stranded antiparallel β-sheet, which forms a beta-barrel that can be used for transport and storage of diverse hydrophobic ligands ...
Armanmehr, S. +2 more
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PLoS ONE, 2020 Calprotectin is a heterodimeric protein complex with two subunits called S100A8/A9. The protein has an essential role in inflammation process and various human diseases.
Nematollah Gheibi +3 more
doaj +1 more source
Alzheimer’s Research & Therapy, 2017 Background Polyunsaturated fatty acids play a crucial role in neuronal function, and the modification of these compounds in the brain could have an impact on neurodegenerative diseases such as Alzheimer’s disease.
Mélanie H. Thomas +8 more
doaj +1 more source
Hydrocortisone inhibits prostaglandin production but not arachidonic acid release from cultured macrophages [PDF]
, 1984 We have investigated the action of hydrocortisosone on arachidonic acid mobilisation in cultures of mouse peritoneal macrophages, mouse L929 cells and the mouse macrophage-like cell line RAW264.
Clancy +16 more
core +5 more sources
Phospholipid, arachidonate and eicosanoid signaling in schizophrenia
Oilseeds and fats, crops and lipids, 2016 This paper reviews the potential role of arachidonic acid in the pathophysiology of schizophrenia. We discuss how abnormal levels of arachidonic acid may arise, and how dysregulation of signaling molecules derived from it have the potential to disrupt ...
Messamore Erik, Yao Jeffrey K.
doaj +1 more source
Nature Communications, 2023 Colonocyte metabolism shapes the microbiome. Metabolites are the main mediators of information exchange between intestine and microbial communities. Arachidonic acid (AA) is an essential polyunsaturated fatty acid and its role in colorectal cancer (CRC ...
Chunjie Xu +12 more
doaj +1 more source
Arachidonic Acid Production by Fungi [PDF]
Applied and Environmental Microbiology, 1991 After preliminary screening, Mortierella alpina and Mortierella elongata were compared with respect to arachidonic acid content. M. alpina ATCC 16266 produced 2.1 g of arachidonic acid per liter in media containing 10% glucose while the highest percentage of ...
Pratima Bajpai +2 more
openaire +3 more sources
Dietary arachidonic acid: a Janus face actor in brain and Alzheimer’s disease?
Oilseeds and fats, crops and lipids, 2018 Arachidonic acid is the second polyunsaturated fatty acid in brain and the first one belonging to the ω-6 series. Dietary intakes of arachidonic are between 50 and 300 mg/day in western diets but they might be underestimated. Triglycerides from fat would
Pinchaud Katleen +2 more
doaj +1 more source
Three-year tracking of fatty acid composition of plasma phospholipids in healthy children [PDF]
, 2007 Objectives: The fatty acid composition of plasma phospholipids reflects the dietary fatty acid intake as well as endogenous turnover. We aimed at investigating the potential tracking of plasma phospholipid fatty acid composition in children that ...
Andersson A +35 more
core +1 more source
Probing the Electrostatic and Steric Requirements for Substrate Binding in Human Platelet-Type 12-Lipoxygenase. [PDF]
, 2019 Human platelet ALOX12 (hALOX12 or h12-LOX) has been implicated in a variety of human diseases. The present study investigates the active site of hALOX12 to more thoroughly understand how it positions the substrate and achieves nearly perfect regio- and ...
Aleem, Ansari Mukhtar +7 more
core +2 more sources