Docosahexaenoic and Arachidonic Acids as Neuroprotective Nutrients throughout the Life Cycle. [PDF]
The role of docosahexaenoic acid (DHA) and arachidonic acid (AA) in neurogenesis and brain development throughout the life cycle is fundamental. DHA and AA are long-chain polyunsaturated fatty acids (LCPUFA) vital for many human physiological processes ...
Sambra V+4 more
europepmc +2 more sources
Metabolism pathways of arachidonic acids: mechanisms and potential therapeutic targets. [PDF]
The arachidonic acid (AA) pathway plays a key role in cardiovascular biology, carcinogenesis, and many inflammatory diseases, such as asthma, arthritis, etc.
Wang B+8 more
europepmc +2 more sources
Bifidobacterium breve with α-Linolenic Acid and Linoleic Acid Alters Fatty Acid Metabolism in the Maternal Separation Model of Irritable Bowel Syndrome [PDF]
peer-reviewedThe aim of this study was to compare the impact of dietary supplementation with a Bifidobacterium breve strain together with linoleic acid & α-linolenic acid, for 7 weeks, on colonic sensitivity and fatty acid metabolism in rats.
Barrett, Eoin+10 more
core +14 more sources
Effects of Arachidonic Acid Metabolites on Cardiovascular Health and Disease
Arachidonic acid (AA) is an essential fatty acid that is released by phospholipids in cell membranes and metabolized by cyclooxygenase (COX), cytochrome P450 (CYP) enzymes, and lipid oxygenase (LOX) pathways to regulate complex cardiovascular function ...
Yan Zhou+3 more
semanticscholar +1 more source
Arachidonic Acid in Human Milk [PDF]
Breastfeeding is universally recommended as the optimal choice of infant feeding and consequently human milk has been extensively investigated to unravel its unique nutrient profile. The human milk lipid composition is unique and supplies specifically long-chain polyunsaturated fatty acids (LC-PUFAs), in particular, arachidonic acid (ARA, 20:4n–6) and ...
Norman Salem, Peter Van Dael
openaire +2 more sources
Arachidonic acid in Alzheimer's disease [PDF]
Alzheimer’s disease is a very complex disease in which neuroinflammation and synaptic dysfunctions play a critical role in association with the two well-known molecular agents of the disease, the Aβ1-42 peptide oligomers and the hyperphosphorylated tau protein.
Nicolas Vitale+10 more
openaire +3 more sources
The Contribution of Cytosolic Group IVA and Calcium-Independent Group VIA Phospholipase A2s to Adrenic Acid Mobilization in Murine Macrophages [PDF]
Producción CientíficaAdrenic acid (AA), the 2-carbon elongation product of arachidonic acid, is present at significant levels in membrane phospholipids of mouse peritoneal macrophages.
Balboa García, María Ángeles+6 more
core +1 more source
Is arachidonic acid an endoschistosomicide?
Schistosoma mansoni and Schistosoma haematobium are intravascular, parasitic flatworms that infect >250 million people in 70 developing countries, yet not all people of the same community and household are afflicted. Regarding laboratory rodents, mice but not rats are susceptible to infection with S.
Rashika El Ridi+4 more
openaire +4 more sources
The essentiality of arachidonic acid and docosahexaenoic acid [PDF]
The purpose of this review is to correlate the clinical finding that patients receiving parenteral nutrition with a fish oil-based lipid emulsion do not develop essential fatty acid deficiency (EFAD) with an experimental murine model, thus showing that arachidonic acid (AA) and docosahexaenoic acid (DHA) are likely to be the essential fatty acids ...
Mark Puder+4 more
openaire +3 more sources
Fate of linoleic, arachidonic, and docosa-7,10,13,16-tetraenoic acids in rat testicles [PDF]
A comparative study was made on the fate of linoleic, arachidonic, and docosa-7,10,13,16-tetraenoic acids in various subcellular fractions of liver and testis from rats of different ages.
Ayala, Sixta+4 more
core +1 more source