Metabolism pathways of arachidonic acids: mechanisms and potential therapeutic targets [PDF]
Signal Transduction and Targeted Therapy, 2021 The arachidonic acid (AA) pathway plays a key role in cardiovascular biology, carcinogenesis, and many inflammatory diseases, such as asthma, arthritis, etc.
Bei Wang +8 more
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Evaluation of ω-alkynyl-labeled linoleic and arachidonic acids as substrates for recombinant lipoxygenase pathway enzymes. [PDF]
Biochim Biophys Acta Mol Cell Biol Lipids, 2023 Noguchi S +6 more
europepmc +3 more sources
Deuterated Arachidonic Acids Library for Regulation of Inflammation and Controlled Synthesis of Eicosanoids: An In Vitro Study [PDF]
Molecules, 2018 The synthesis of signal lipids, including eicosanoids, is not fully understood, although it is key to the modulation of various inflammatory states.
Dmitry V. Chistyakov +9 more
doaj +2 more sources
The role of bioactive lipids and eicosanoid metabolites in acute exercise in adults: Insights into human cardiorespiratory fitness [PDF]
Physiological ReportsThe molecular mechanisms underlying the salutary effects of exercise remain incompletely understood. Exerkines are signaling molecules with autocrine, paracrine, or endocrine effects released in response to exercise. Specific eicosanoids, small bioactive
Mythri Ambatipudi +8 more
doaj +2 more sources
The Polyunsaturated Fatty Acids Arachidonic Acid and Docosahexaenoic Acid Induce Mouse Dendritic Cells Maturation but Reduce T-Cell Responses In Vitro. [PDF]
PLoS ONE, 2015 Long-chain polyunsaturated fatty acids (PUFAs) might regulate T-cell activation and lineage commitment. Here, we measured the effects of omega-3 (n-3), n-6 and n-9 fatty acids on the interaction between dendritic cells (DCs) and naïve T cells. Spleen DCs
Johan A Carlsson +3 more
doaj +1 more source
Bifidobacterium breve with α-Linolenic Acid and Linoleic Acid Alters Fatty Acid Metabolism in the Maternal Separation Model of Irritable Bowel Syndrome [PDF]
, 2012 peer-reviewedThe aim of this study was to compare the impact of dietary supplementation with a Bifidobacterium breve strain together with linoleic acid & α-linolenic acid, for 7 weeks, on colonic sensitivity and fatty acid metabolism in rats.
Barrett, Eoin +10 more
core +8 more sources
Biomolecules, 2020 Adrenic acid (AA), the 2-carbon elongation product of arachidonic acid, is present at significant levels in membrane phospholipids of mouse peritoneal macrophages.
Patricia Monge +6 more
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Emerging roles of polyunsaturated fatty acid synthesis pathway in colorectal cancer
Animal Cells and Systems, 2023 The development of colorectal cancer typically involves the accumulated influences of genetic alterations, medical issues, lifestyle, and diet. Dietary fatty acids appear to affect the tumorigenesis and progression of colorectal cancer.
Young-Ah Moon
doaj +1 more source
Proximate composition and fatty acids profiling of Seahorse originated from Simeulue, Aceh-Indonesia [PDF]
E3S Web of Conferences, 2022 The aim of this study was to determine the proximate composition, quantitative of fatty acids analysis as well as the content in the seahorse sample, Hippocampus sp which originated from Sibigo waters, Simeulue, Aceh, Indonesia.
Abdullah Abbas Muhammadar +4 more
doaj +1 more source
Frontiers in Pediatrics, 2021 Steroid-sensitive nephrotic syndrome is an immunological disorder mediated by still poorly defined circulating factor(s) that target the podocyte and damage the filtration barrier.
Stefano Turolo +14 more
doaj +1 more source