Results 101 to 110 of about 77,615 (306)

The role of bioactive lipids and eicosanoid metabolites in acute exercise in adults: Insights into human cardiorespiratory fitness

open access: yesPhysiological Reports
The molecular mechanisms underlying the salutary effects of exercise remain incompletely understood. Exerkines are signaling molecules with autocrine, paracrine, or endocrine effects released in response to exercise. Specific eicosanoids, small bioactive
Mythri Ambatipudi   +8 more
doaj   +1 more source

METABOLISM OF ARACHIDONIC ACID IN PHOSPHOLIPID

open access: yesThe Keio Journal of Medicine, 1966
After albino rats were starved or fed with the fat and pyridoxine deficient diet, linoleic, linolenic and arachidonic acids and pyridoxine were administered. The amount of polyunsaturated fatty acids in phospholipid of the liver and muscle was then determined and the following results were obtained.1) Even if rats were fed on the fat deficient diet or ...
openaire   +3 more sources

Deregulation of Arachidonic Acid Metabolism CYP450 Pathway is Associated with Microvascular Invasion in Hepatocellular Carcinoma

open access: green, 2022
Yang Jin   +8 more
openalex   +1 more source

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

open access: yesIbrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Systemic Lipid Peroxidation and Colorectal Cancer Risk: A Time‐Varying Relationship

open access: yesInternational Journal of Cancer, EarlyView.
Experimental studies in animals suggest that oxidative stress (OxS) declines as cancer progresses. Whether this occurs in humans, however, remains unclear. The authors of the present study addressed this question by analyzing lipid, DNA, and RNA oxidation biomarkers in relation to colorectal cancer (CRC) risk in patients from Shanghai and the United ...
Gong Yang   +8 more
wiley   +1 more source

Probiotics‐derived postbiotics improve host metabolic syndrome by activating the adipocyte thermogenic signaling pathway in high‐fat diet‐fed mice

open access: yesiMetaOmics, EarlyView.
This schematic illustrates how probiotics‐derived postbiotics (PLBK®1–5) combat high‐fat diet‐induced obesity. Postbiotics remodel gut microbiota, boosting beneficial metabolites. These metabolites activate adipocyte thermogenesis (Ucp1/AMPK pathway), resulting in reduced body weight, improved insulin sensitivity, and alleviated hepatic steatosis in ...
Ye Tian   +7 more
wiley   +1 more source

Effects of Arachidonic Acid and Its Metabolites on Functional Beta-Cell Mass [PDF]

open access: gold, 2022
Karin J. Bosma   +3 more
openalex   +1 more source

Changes in the gut microbiome during fasting‐induced molting and its effects on gut–liver function

open access: yesiMetaOmics, EarlyView.
During fasting, harmful microbiota and metabolites rise, triggering intestinal injury and activation of the TGF‐β signaling pathway, which enhances intestinal stem cell proliferation. Concurrently, hepatic function declines, indicated by increased hepatic and serum bile acids and upregulation of the non‐classical bile acid synthesis pathway.
Hao Zhang   +11 more
wiley   +1 more source

Early Enteral Administration of a Complex Lipid Emulsion Supplement Prevents Postnatal Deficits in Docosahexaenoic and Arachidonic Acids and Increases Tissue Accretion of Lipophilic Nutrients in Preterm Piglets. [PDF]

open access: yesJPEN J Parenter Enteral Nutr, 2020
Akinsulire O   +20 more
europepmc   +1 more source

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