Results 51 to 60 of about 127,455 (327)

Arachidonic Acid Production by Fungi [PDF]

Applied and Environmental Microbiology, 1991
After preliminary screening, Mortierella alpina and Mortierella elongata were compared with respect to arachidonic acid content. M. alpina ATCC 16266 produced 2.1 g of arachidonic acid per liter in media containing 10% glucose while the highest percentage of ...
P K, Bajpai, P, Bajpai, O P, Ward
openaire   +2 more sources

Elevated Apolipoprotein E Expression in Hippocampal Microglia Drives Temporal Lobe Epilepsy Progression

Advanced Science, EarlyView.
In temporal lobe epilepsy, hippocampal APOE is markedly upregulated predominantly in microglia. APOE overexpression in microglia drives TLR4 and cGAS/STING‐dependent neuroinflammation, engages bidirectional crosstalk with neurons and astrocytes, increases neuronal excitability, and perturbs hippocampal lipid metabolism. These findings suggest that APOE‐
Jianwei Shi, Zesheng Li, Xin Sun, Yanfeng Yang, Yumin Luo, Ziang Song, Hengxin Dong, Lei Jin, Jing Xie, Yongzhi Shan, Guoguang Zhao   +10 more
wiley   +1 more source

The effects of the unsaturated degree of long-chain fatty acids on the rumen microbial protein content and the activities of transaminases and dehydrogenase in vitro

Journal of Integrative Agriculture, 2016
: This study investigated the effects of the degree of unsaturation (unsaturity) of long-chain fatty acids on microbial protein content and the activities of transaminases and dehydrogenase in vitro using goat rumen fluid as the cultural medium.
Jian GAO, Yu-jia JING, Meng-zhi WANG, Liang-feng SHI, Shi-min LIU   +4 more
doaj   +1 more source

THE INHIBITORY EFFECT OF PROPOLIS AND CAFFEIC ACID PHENETHYLESTER ON CYCLOOXYGENASE ACTIVITY IN J774 MACROPHAGES. [PDF]

, 2002
The effect of an ethanolic extract of propolis, with and without CAPE, and some of its components on cyclooxygenase (COX-1 and COX-2) activity in J774 macrophages has been investigated.
BORRELLI, FRANCESCA, LIGRESTI A., LONGO R., ROSSI, ANTONIETTA, RUSSO A., SAUTEBIN, LIDIA   +5 more
core   +1 more source

Lactylated SPTAN1 Accelerates Hepatocellular Carcinoma Progression by Promoting NOTCH1/HES1 Activation and Immunosuppression

Advanced Science, EarlyView.
This study identifies SPTAN1‐kla as a novel oncogenic driver in HBV‐driven HCC, linking metabolic, epigenetic, and immune mechanisms. SPTAN1‐kla promotes HCC progression via NOTCH1/HES1 activation and immunosuppression. Findings highlight that targeting SPTAN1‐kla provides a framework for HCC treatment to improve clinical outcomes in HBV infected ...
Zengbin Wang, Dongjie Ye, Linqing Wu, Jiayu Liu, Banglun Pan, Zhu Zhang, Xiaoxia Zhang, Yuxin Yao, Nanhong Tang   +8 more
wiley   +1 more source

Plasmalogens in Innate Immune Cells: From Arachidonate Signaling to Ferroptosis

Biomolecules
Polyunsaturated fatty acids such as arachidonic acid are indispensable components of innate immune signaling. Plasmalogens are glycerophospholipids with a vinyl ether bond in the sn-1 position of the glycerol backbone instead of the more common sn-1 ...
Jesús Balsinde, María A. Balboa
doaj   +1 more source

Neutrophil Extracellular Trap Reprograms Cancer Metabolism to Form a Metastatic Niche Promoting Non‐Small Cell Lung Cancer Brain Metastasis

Advanced Science, EarlyView.
This study mainly combines spatial/single‐cell transcriptomics and metabolomics to reveal LOX+ Malig‐5 as NSCLC brain metastasis‐initiating cells, forming a niche with NET‐releasing neutrophils via the NET‐KRT10 axis. The metastatic niche is involved with metabolic reprogramming, with palmitic acid serving as a key metabolite.
Bo Chen, Karrie M. Kiang, Fangkun Liu, Chuntao Li, Xizhe Li, Chen Weiwei, Xin Fu, Gelei Xiao, Jingyi Sun, Erhan Da, Junbo Liao, Hongshu Zhou, Li Meng, Li Zhou, Tao Song, Longbo Zhang, Gilberto Ka‐Kit Leung, Liyang Zhang   +17 more
wiley   +1 more source

Ameliorative effects of polyunsaturated fatty acids against palmitic acid-induced insulin resistance in L6 skeletal muscle cells

Lipids in Health and Disease, 2012
Background Fatty acid-induced insulin resistance and impaired glucose uptake activity in muscle cells are fundamental events in the development of type 2 diabetes and hyperglycemia.
Sawada Keisuke, Kawabata Kyuichi, Yamashita Takatoshi, Kawasaki Kengo, Yamamoto Norio, Ashida Hitoshi   +5 more
doaj   +1 more source

The Use of Dietary Additives in Fish Stress Mitigation: Comparative Endocrine and Physiological Responses [PDF]

, 2019
In the last years, studies on stress attenuation in fish have progressively grown. This is mainly due to the interest of institutions, producers, aquarists and consumers in improving the welfare of farmed fish.
Abdel-Tawwab, Alderman, Alves Martins, Alves Martins, Alves Martins, Aragão, Araújo, Azeredo, Azeredo, Babaei, Baltzegar, Basic, Basic, Belo, Benítez-Dorta, Berntssen, Berntssen, Betancor, Blazer, Brake, Bransden, Cabanillas-Gámez, Cardoso, Chen, Chen, Chen, Cheng, Conceição, Conde-Sieira, Cosgrove, Costas, Costas, Costas, Costas, Costas, Costas, Dabrowska, Dabrowski, Davis, Dhabhar, Dimitroglou, Doyon, Eissa, Fabbri, Falahatkar, Faught, Fletcher, Forsatkar, Fracalossi, Fu, Fuchs, Ganga, Ganga, Ganga, Gil, González-Silvera, Gorissen, Gorissen, Gorissen, Gorissen, Grimble, Grimble, Guimarães, Habte-Tsion, Halver, Harpaz, Herrera, Hog¨lund, Hooley, Hoseini, Hoseini, Hoseinifar, Hseu, Hwang, Höglund, Höglund, Imanpoor, Iwama, Izquierdo, Jia, Kanazawa, Kenari, Khassaf, Kiilerich, Kim, Kim, Kiron, Kitabchi, Koshio, Koven, Kumar, Kumar, Küçükbay, Lall, Lanes, Leonardi, Leong, Lepage, Lepage, Lepage, Li, Li, Li, Li, Liu, Liu, Liu, Liu, Lochmann, Long, Martin, Martins, Martins, McDowell, McKenzie, McKenzie, Mechlaoui, Melnyk-Lamont, Miao, Mommsen, Montero, Montero, Montero, Montero, Montero, Morandini, Morrow, Naderi, Nye, Olmos-Soto, Palermo, Papoutsoglou, Pardue, Pérez-Jiménez, Pérez-Sánchez, Read, Rezek, Rider, Ringø, Rønnestad, Sakai, Saleh, Sang, Schreck, Schreck, Skrzynska, Solano, Sándor, Tahmasebi-Kohyani, Tejpal, Thompson, Tian, Tocher, Torrecillas, Torrecillas, Trenzado, Trenzado, Trushenski, Van Anholt, Van Anholt, Verburg-van Kemenade, Vijayan, Wang, Watanabe, Weirich, Winberg, Wolkers, Wu, Xie, Xu, Yao, Yoshizawa, Yousefi, Zacharieva   +173 more
core   +2 more sources

Arachidonic acid in cell signaling [PDF]

Current Opinion in Cell Biology, 1993
Important advances have recently been made in our understanding of the arachidonic acid cascade. The molecular characterization of different forms of phospholipase A2 indicates that multiple pathways are involved in the release of arachidonic acid evoked by physiological or pathological stimuli.
openaire   +4 more sources