Results 71 to 80 of about 65,432 (256)

Effects of lipoteichoic and arachidonic acids on the immune-regulatory mechanism of bovine mammary epithelial cells using multi-omics analysis. [PDF]

Front Vet Sci, 2022
Dong W, Chen Y, Zhang Q, Zhao X, Liu P, He H, Lu T, He Y, Du X, Hu J, Zhao X, Zhang Y.   +11 more
europepmc   +1 more source

Evaluation of a pantoprazole and 4‐desmethylpantoprazole‐sulfate metabolic ratio as a novel CYP2C19 phenotyping method

British Journal of Clinical Pharmacology, EarlyView.
Aims CYP2C19 is one of the most important pharmacogenes, and its activity is highly variable due to factors such as genetics or drug–drug interactions. Due to the lack of an appropriate endogenous CYP2C19 biomarker, surrogate methods to assess its activity are warranted.
Julian Peter Müller, Vladimir N. Belov, Sabrina Yamoune, Bob Miller, Mohammed Hasoumi, Jolanta Tupiec, Thea Laurentius, L. Cornelius Bollheimer, Julia C. Stingl, Katja S. Just   +9 more
wiley   +1 more source

Docosahexaenoic and Arachidonic Acids as Neuroprotective Nutrients throughout the Life Cycle. [PDF]

Nutrients, 2021
Sambra V, Echeverria F, Valenzuela A, Chouinard-Watkins R, Valenzuela R.   +4 more
europepmc   +1 more source

Pt‐TiO2 mesoporous nanosystem co‐delivering phlorezin enables synergistic sonodynamic‐chemoimmunotherapy for hepatocellular carcinoma via directly targeting DDX5 and metabolic reprogramming modulation

BMEMat, EarlyView.
Abstract Hepatocellular carcinoma (HCC), ranking as the third leading cause of cancer‐related mortality globally, continues to pose significant therapeutic challenges. Here, we developed an innovative nanosystem, Phl@PT, based on Pt‐TiO2 nanoparticles for the co‐delivery of Phlorezin, presenting a novel approach for HCC treatment through sonodynamic ...
Kairui Liu, Bo Zhang, Yue Wan, Zhiru Yang, Abdusami Abdurahman, Mengxin He, Shengtao Hu, Yi Zhang, Xiaoke Li, Jin Chang, Jun Kang, Liren Liu, Wanghua Liu, Shao Li   +13 more
wiley   +1 more source

Acculturation and Plasma Fatty Acid Concentrations in Hispanic and Chinese-American Adults: The Multi-Ethnic Study of Atherosclerosis.

PLoS ONE, 2016
BackgroundAcculturation to the U.S. is associated with increased risk of cardiovascular disease, but the etiologic pathways are not fully understood. Plasma fatty acid levels exhibit ethnic differences and are emerging as biomarkers and predictors of ...
Cassandra S Diep, Rozenn N Lemaitre, Tzu-An Chen, Tom Baranowski, Pamela L Lutsey, Ani W Manichaikul, Stephen S Rich, David E St-Jules, Brian T Steffen, Michael Y Tsai, David S Siscovick, Alexis C Frazier-Wood   +11 more
doaj   +1 more source

A bioinspired catalytic nanoplatform for ferroptosis‐immunotherapy synergy in metastatic cancer

BMEMat, EarlyView.
The bioinspired nanoplatform MnMSN@MnP‐PEG co‐delivers manganese peroxidase and manganese ions to synergistically induce immunogenic ferroptosis and activate the cGAS‐STING pathway, eliciting potent antitumor immunity against primary and metastatic tumors.
Panpan Xue, Hai Cai, Ying Sun, Yaxin Ma, Siyuan Liu, Jinying Zhu, Yan Chen, Xuemei Zeng, Shuangqian Yan   +8 more
wiley   +1 more source

LONG-CHAIN POLYUNSATURATED FATTY ACIDS AND THEIR ROLE IN CHILDREN NOURISHMENT

Вопросы современной педиатрии, 2012
The article deals with the mechanisms of metabolism of linoleic and α-linoleic polyunsaturated fatty acids as precursors of long-chain polyunsaturated fatty acids — arachidonic (ω-6 family) and docosahexaenoic acid (ω-3 famyli).
T. E. Borovik, S. G. Gribakin, V. A. Skvortsova, N. N. Semenova, T. N. Stepanova, N. G. Zvonkova   +5 more
doaj   +1 more source

Serum Eicosapentaenoic and Arachidonic Acids Concentration and Cognitive Function in Patients With Coronary Artery Disease. [PDF]

Basic Clin Neurosci, 2021
Yoosefee S, Rahimi M, Razavinia FS, Vahedian M, Bagheri AR.   +4 more
europepmc   +1 more source

Arachidonic acid as a bioactive molecule [PDF]

Journal of Clinical Investigation, 2001
Arachidonic acid is a slippery molecule that owes its mobility to its four cis double bonds. These are the source of its flexibility, keeping the pure fatty acid liquid, even at subzero temperatures, and helping to give mammalian cell membranes their correct fluidity at physiological temperatures.
openaire   +2 more sources

Plasma Exosome Metabolomics Reveal Stage‐Specific Alterations in Elderly Women With Premetabolic and Metabolic Syndrome

Chronic Diseases and Translational Medicine, EarlyView.
Shared differential metabolites identified across the three sample groups. (A) Venn diagram of differential metabolites between the two comparison groups; Based on the detected levels of these overlapping differential metabolites, (B) d‐Arabitol, (C) Triclosan, (D) Iloprost, (E) Tetracosanoic acid, and (F) Omeprazole sulfone. Box plots were constructed
Mengtao Qian, Dan Nie, Qianyi Gao, Xingbo Mo, Huan Zhang   +4 more
wiley   +1 more source