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Latest Advances in Arbovirus Diagnostics
Microorganisms, 2023 Arboviruses are a diverse family of vector-borne pathogens that include members of the Flaviviridae, Togaviridae, Phenuviridae, Peribunyaviridae, Reoviridae, Asfarviridae, Rhabdoviridae, Orthomyxoviridae and Poxviridae families.
Jano Varghese, Imesh De Silva, D. Millar
semanticscholar +4 more sources
An mRNA vaccine against rabies provides strong and durable protection in mice
Frontiers in Immunology, 2023 IntroductionRabies is a serious public health problem worldwide for which an effective treatment method is lacking but can be prevented by vaccines.
Miao Li +22 more
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Construction of a Dengue NanoLuc Reporter Virus for In Vivo Live Imaging in Mice
Viruses, 2022 Since the first isolation in 1943, the dengue virus (DENV) has spread throughout the world, but effective antiviral drugs or vaccines are still not available. To provide a more stable reporter DENV for vaccine development and antiviral drug screening, we
Enyue Fang +10 more
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The increasing complexity of arbovirus serology: An in-depth systematic review on cross-reactivity
PLoS Neglected Tropical Diseases, 2023 Diagnosis of arbovirus infection or exposure by antibody testing is becoming increasingly difficult due to global expansion of arboviruses, which induce antibodies that may (cross-)react in serological assays.
Louella M R Kasbergen +4 more
semanticscholar +1 more source
Factors Affecting Arbovirus Midgut Escape in Mosquitoes
Pathogens, 2023 Arboviral diseases spread by mosquitoes cause significant morbidity and mortality throughout much of the world. The treatment and prevention of these diseases through medication and vaccination is often limited, which makes controlling arboviruses at the
Alexis Carpenter, R. J. Clem
semanticscholar +1 more source
Using Background Sequencing Data to Anticipate DENV-1 Circulation in the Lao PDR
Microorganisms, 2021 Since its first detection in 1979, dengue fever has been considered a major public health issue in the Lao People’s Democratic Republic (PDR). Dengue virus (DENV) serotype 1 was the cause of an epidemic in 2010–2011.
Elodie Calvez +11 more
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Zika virus and temperature modulate Elizabethkingia anophelis in Aedes albopictus
Parasites & Vectors, 2021 Background Vector-borne pathogens must survive and replicate in the hostile environment of an insect’s midgut before successful dissemination. Midgut microbiota interfere with pathogen infection by activating the basal immunity of the mosquito and by ...
Maria G. Onyango +9 more
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Aedes aegypti Argonaute 2 controls arbovirus infection and host mortality
Nature Communications, 2023 Ae. aegypti mosquitoes transmit some of the most important human viral diseases that are responsible for a significant public health burden worldwide. The small interfering RNA (siRNA) pathway is considered the major antiviral defense system in insects ...
S. Dong, George Dimopoulos
semanticscholar +1 more source
Parasites & Vectors, 2020 Background Progress made in the control of malaria vectors globally is largely due to the use of insecticides. However, success in the fight against malaria has slowed down or even stalled due to a host of factors including insecticide resistance.
Okechukwu Chukwuekezie +17 more
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Emerging Microbes and Infections, 2022 West Nile virus (WNV; Flavivirus, Flaviviridae) was introduced to New York State (NYS) in 1999 and rapidly expanded its range through the continental United States (US). Apart from the displacement of the introductory NY99 genotype with the WN02 genotype,
Sean M. Bialosuknia +8 more
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