Arbutin as a Skin Depigmenting Agent with Antimelanogenic and Antioxidant Properties
Antioxidants, 2021 Arbutin is a compound of hydroquinone and D-glucose, and it has been over 30 years since there have been serious studies on the skin lightening action of this substance.
Yong Chool Boo
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Combination of enzyme engineering and quorum sensing system for efficient de novo biosynthesis of β-arbutin in Escherichia coli [PDF]
Synthetic and Systems Biotechnologyβ-Arbutin is a plant-derived glycoside with various biological activities, which has been applied in pharmaceuticals and whitening cosmetics. Uneven carbon flux distribution and the low catalytic efficiency of arbutin synthase limit the biosynthesis of β-
Zhuoyuan Liu +6 more
doaj +2 more sources
Chemical and Biocatalytic Routes to Arbutin † [PDF]
Molecules, 2019 Arbutin (also called β-arbutin) is a natural product occurring in the leaves of a variety of different plants, the bearberries of the Ericaceae and Saxifragaceae families being prominent examples.
Hangyu Zhou +3 more
doaj +4 more sources
Arbutin attenuates nephrotoxicity induced by gentamicin [PDF]
Avicenna Journal of Phytomedicine, 2021 Objective: In this study, the impact of arbutin was examined in a gentamicin (GM)-induced nephrotoxicity model. Materials and Methods: Forty adult male Wistar rats were randomly assigned to five groups including control group; GM group, and three groups ...
Elnaz Emadi +5 more
doaj +3 more sources
The phytochemical arbutin exerts potent anti-Toxoplasma effects through activation of cell-autonomous defense mechanisms while attenuating inflammation. [PDF]
PLoS Neglected Tropical DiseasesBackgroundPlant-derived natural products have emerged as promising candidates for developing novel anti-toxoplasmosis drugs. This study aimed to elucidate the role and mechanism of the phytochemical arbutin in the control of T.
Zhuanzhuan Liu +9 more
doaj +2 more sources
Arbutin: Occurrence in Plants, and Its Potential as an Anticancer Agent
Molecules, 2022 Arbutin, a hydroquinone glucoside, has been detected in ca. 50 plant families, especially in the plants of the Asteraceae, Ericaceae, Proteaceae and Rosaceae families. It is one of the most widely used natural skin-whitening agents.
Lutfun Nahar +2 more
exaly +3 more sources
Antimicrobial action of α-arbutin, β-arbutin and hydroquinone: truth and fiction
Annals of Mechnikov's InstituteIntroduction. The leaves of lingonberry and bearberry are used in medicine for the treatment and prevention of urological infectious diseases due to the presence of diuretic and uroseptic action.
Oleksandr Maslov +6 more
doaj +3 more sources
Arbutin as a potential nephroprotective agent: Dose-related effects in renal ischemia-reperfusion injury [PDF]
Biomolecules & BiomedicineIschemia-reperfusion injury (IRI) presents a complex pathophysiology characterized by oxidative stress and inflammation. Arbutin, widely recognized for its use in skin whitening, also exhibits antioxidant, anti-inflammatory, and anticancer properties ...
Ferhat Sirinyildiz +3 more
doaj +2 more sources
Arbutin improves gut development and serum lipids via Lactobacillus intestinalis
Frontiers in Nutrition, 2022 Arbutin has been widely studied in whitening, anti-inflammatory, and antioxidant. However, the interaction between arbutin and intestinal microbes has been rarely studied.
Jie Ma +4 more
doaj +1 more source
Molecular modeling and phenoloxidase inhibitory activity of arbutin and arbutin undecylenic acid ester [PDF]
Biochemical and Biophysical Research Communications, 2021 Excessive melanin formation has been linked to various skin disorders such as hyperpigmentation and skin cancer. Tyrosinase is the most prominent target for inhibitors of melanin production. In this study, we investigated whether arbutin and its prodrug, arbutin undecylenic acid ester, might inhibit phenoloxidase (PO), a tyrosinase-like enzyme ...
Ayu Masyita +8 more
openaire +2 more sources